Collections Mon-Wed ONLY. Specimens must be received at Mayo Clinic Laboratories prior to 4 pm on Fridays.
Collect
Specimen Required: Two separate EDTA specimens are required: 1 refrigerated and 1 at ambient transport temperature.
Specimen Type: Whole blood for TBBS / Quantitative Lymphocyte Subsets: T, B, and NK Container/Tube: 4 mL Lavender top (EDTA) Specimen Volume: 3 mL Collection Instructions:
1. Send specimen in original tube. Do not aliquot.
2. Label specimen as blood for TBBS / Quantitative Lymphocyte Subsets: T, B, and NK. Specimen Stability Information: Ambient <52 hours
Specimen Type: Whole blood for IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood Container/Tube: Lavender top (EDTA) Specimen Volume:
< or =14 years: 4 mL
>14 years: 10 mL Collection Instructions:
1. Send specimen in original tube. Do not aliquot.
2. Label specimen as blood for IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood. Specimen Stability Information: Refrigerated <48 hours.
Minimum Volumes
TBBS: 1 mL
IABC
< or =14 years: 3 mL
> 14 years: 5 mL
Useful for screening for common variable immunodeficiency (CVID) and hyper-IgM syndromes.
Assessing B-cell subset reconstitution after stem cell or bone marrow transplant.
Assessing response to B-cell-depleting immunotherapy.
Identifying defects in transmembrane activator and calcim modulator and cyclophilin ligand (CAML) interactor (TACI) and B-cell-activating factor receptor (BAFF-R) in patients presenting with clinical symptoms and with laboratory features consistent with CVID.
This test is not indicated for the evaluation of lymphoproliferative disorders (eg, leukemia, lymphoma, Multiple myeloma).
T- and B-Cell Quantitation by Flow Cytometry
86355-B cells, total count
86357-Natural killer (NK) cells, total count
86359-T cells, total count
86360-Absolute CD4/CD8 count with ratio
B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood
86356 x7 - Mononuclear cell antigen, quantitative
Common Variable Immunodeficiency Confirmation Flow Panel
88184-Flow cytometry, first marker (if appropriate)
88185 x 2-Flow cytometry, each additional marker (if appropriate)
Collection
Alias
Epic: EP1042; Mayo: IABCS
Collections Mon-Wed ONLY. Specimens must be received at Mayo Clinic Laboratories prior to 4 pm on Fridays.
Collect
Specimen Required: Two separate EDTA specimens are required: 1 refrigerated and 1 at ambient transport temperature.
Specimen Type: Whole blood for TBBS / Quantitative Lymphocyte Subsets: T, B, and NK Container/Tube: 4 mL Lavender top (EDTA) Specimen Volume: 3 mL Collection Instructions:
1. Send specimen in original tube. Do not aliquot.
2. Label specimen as blood for TBBS / Quantitative Lymphocyte Subsets: T, B, and NK. Specimen Stability Information: Ambient <52 hours
Specimen Type: Whole blood for IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood Container/Tube: Lavender top (EDTA) Specimen Volume:
< or =14 years: 4 mL
>14 years: 10 mL Collection Instructions:
1. Send specimen in original tube. Do not aliquot.
2. Label specimen as blood for IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood. Specimen Stability Information: Refrigerated <48 hours.
Minimum Volumes
TBBS: 1 mL
IABC
< or =14 years: 3 mL
> 14 years: 5 mL
Useful for screening for common variable immunodeficiency (CVID) and hyper-IgM syndromes.
Assessing B-cell subset reconstitution after stem cell or bone marrow transplant.
Assessing response to B-cell-depleting immunotherapy.
Identifying defects in transmembrane activator and calcim modulator and cyclophilin ligand (CAML) interactor (TACI) and B-cell-activating factor receptor (BAFF-R) in patients presenting with clinical symptoms and with laboratory features consistent with CVID.
This test is not indicated for the evaluation of lymphoproliferative disorders (eg, leukemia, lymphoma, Multiple myeloma).
T- and B-Cell Quantitation by Flow Cytometry
86355-B cells, total count
86357-Natural killer (NK) cells, total count
86359-T cells, total count
86360-Absolute CD4/CD8 count with ratio
B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood
86356 x7 - Mononuclear cell antigen, quantitative
Common Variable Immunodeficiency Confirmation Flow Panel
88184-Flow cytometry, first marker (if appropriate)
88185 x 2-Flow cytometry, each additional marker (if appropriate)
