Supplies: HPV SurePath Transport Tube 13 mL (T710) Specimen Type: Cervical (endocervical or ectocervical) orVaginal Specimen Volume: 1.5 mL
Collection Instructions:
Aliquot a minimum of 1 mL SurePath specimen into SurePath HPV aliquot tube.
Bag specimens individually as they have a tendency to leak during transport.
Place labels on the vial and on the bag.
Minimum Volumes
1.0 mL
Unacceptable Conditions
SurePath enriched cell pellet
Storage/Transport Temperature
Ambient
Stability (from collection to initiation)
Ambient: 14 days; Refrigerated: 14 days
Performed
Monday through Friday
Ordering Recommendations
Detection of high-risk (HR) genotypes associated with the development of cervical cancer.
An aid in triaging women with abnormal PAP smear results.
Individual genotyping of human papillomavirus (HPV)-16 and/or HPV-18, if present.
Reported
3-6 days
Notes
Performing Lab: Mayo Clinic Laboratories
Reference Interval
Negative for HPV genotypes 16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68.
Interpretive Data
A positive result indicates the presence of human papillomavirus (HPV) DNA due to 1 or more of the following genotypes: 16, 18, 31, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68.
A negative result indicates the absence of HPV DNA of the targeted genotypes.
For patients with atypical squamous cells of undetrmined significance (ASC-US) Pap smear result and who are positive for high-risk (HR) HPV, consider referral for colposcopy, if clinically indicated.
For women aged 30 years and older with a negative Pap smear result but who are positive for HPV-16 and/or HPV-18, consider referral for colposcopy, if clinically indicated.
For women aged 30 years and older with a negative Pap smear, positive HR HPV test result, but who are negative for HPV-16 and HPV-18, consider repeat testing by both cytology and a HR HPV test in 12 months.
Methodology
Real-Time Polymerase Chain Reaction (PCR)
CPT Codes
87624; G0476 (if appropriate)
Performing Lab
Mayo Clinic Laboratories
Collection
Alias
Epic: LABS20249; Mayo: SHPV
Collect
Supplies: HPV SurePath Transport Tube 13 mL (T710) Specimen Type: Cervical (endocervical or ectocervical) orVaginal Specimen Volume: 1.5 mL
Collection Instructions:
Aliquot a minimum of 1 mL SurePath specimen into SurePath HPV aliquot tube.
Bag specimens individually as they have a tendency to leak during transport.
Place labels on the vial and on the bag.
Minimum Volumes
1.0 mL
Unacceptable Conditions
SurePath enriched cell pellet
Storage/Transport Temperature
Ambient
Stability (from collection to initiation)
Ambient: 14 days; Refrigerated: 14 days
Performed
Monday through Friday
Ordering Recommendations
Detection of high-risk (HR) genotypes associated with the development of cervical cancer.
An aid in triaging women with abnormal PAP smear results.
Individual genotyping of human papillomavirus (HPV)-16 and/or HPV-18, if present.
Reported
3-6 days
Notes
Performing Lab: Mayo Clinic Laboratories
Result Interpretation
Reference Interval
Negative for HPV genotypes 16,18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68.
Interpretive Data
A positive result indicates the presence of human papillomavirus (HPV) DNA due to 1 or more of the following genotypes: 16, 18, 31, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68.
A negative result indicates the absence of HPV DNA of the targeted genotypes.
For patients with atypical squamous cells of undetrmined significance (ASC-US) Pap smear result and who are positive for high-risk (HR) HPV, consider referral for colposcopy, if clinically indicated.
For women aged 30 years and older with a negative Pap smear result but who are positive for HPV-16 and/or HPV-18, consider referral for colposcopy, if clinically indicated.
For women aged 30 years and older with a negative Pap smear, positive HR HPV test result, but who are negative for HPV-16 and HPV-18, consider repeat testing by both cytology and a HR HPV test in 12 months.
