Allow specimen to clot completely before centrifugation. Keep capped at all times.
Specimen Type
Blood
Unacceptable Conditions
Grossly hemolyzed or lipemic specimens.
Stability (from collection to initiation)
After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months
Performed
24 hours, 7 days a week
Ordering Recommendations
Use this immunoassay to measure estradiol in adult premenopausal cisgender females and individuals on estrogen hormone therapies. Not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (eg, aromatase inhibitor) therapy. Not recommended in the evaluation of estradiol status for individuals with protein-binding abnormalities or individuals on hormonal contraception. To compare this test to other estrogen tests, refer to the ARUP Estrogen Tests Comparison table.
Performed
24 hours, 7 days a week
Methodology
Competitive immunoassay format with direct chemiluminescent technology
Synonyms
Estradiol, 17b
CPT Codes
82670
Reference Interval
Effective May 11, 2021
Female
Follicular phase
20-144 pg/mL
Mid Cycle phase
64-357 pg/mL
Luteal Phase
56-214 pg/mL
Post-Menopausal
< 32 pg/mL
MALE: <40 pg/mL
Interpretive Data
This immunoassay is not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (e.g., aromatase inhibitor) therapy. The preferred estradiol test in these cases is Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy) (ARUP test code 0093247).
No reference intervals have been established for prepubertal females or for cisgender males. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0070045
CPT Codes
82670
Performing Lab
Performed at Southwest General
Collection
Collect
Gold top tube - Serum
Specimen Preparation
Allow specimen to clot completely before centrifugation. Keep capped at all times.
Specimen Type
Blood
Unacceptable Conditions
Grossly hemolyzed or lipemic specimens.
Stability (from collection to initiation)
After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months
Performed
24 hours, 7 days a week
Ordering
Ordering Recommendations
Use this immunoassay to measure estradiol in adult premenopausal cisgender females and individuals on estrogen hormone therapies. Not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (eg, aromatase inhibitor) therapy. Not recommended in the evaluation of estradiol status for individuals with protein-binding abnormalities or individuals on hormonal contraception. To compare this test to other estrogen tests, refer to the ARUP Estrogen Tests Comparison table.
Performed
24 hours, 7 days a week
Methodology
Competitive immunoassay format with direct chemiluminescent technology
Synonyms
Estradiol, 17b
CPT Codes
82670
Result Interpretation
Reference Interval
Effective May 11, 2021
Female
Follicular phase
20-144 pg/mL
Mid Cycle phase
64-357 pg/mL
Luteal Phase
56-214 pg/mL
Post-Menopausal
< 32 pg/mL
MALE: <40 pg/mL
Interpretive Data
This immunoassay is not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (e.g., aromatase inhibitor) therapy. The preferred estradiol test in these cases is Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy) (ARUP test code 0093247).
No reference intervals have been established for prepubertal females or for cisgender males. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0070045