Collect

Gold top tube - Serum

Specimen Preparation

Allow specimen to clot completely before centrifugation.  Keep capped at all times.

Specimen Type

Blood

Unacceptable Conditions

Grossly hemolyzed or lipemic specimens.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months

Performed

24 hours, 7 days a week

Ordering Recommendations

Use this immunoassay to measure estradiol in adult premenopausal cisgender females and individuals on estrogen hormone therapies. Not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (eg, aromatase inhibitor) therapy.   Not recommended in the evaluation of estradiol status for individuals with protein-binding abnormalities or individuals on hormonal contraception.  To compare this test to other estrogen tests, refer to the ARUP Estrogen Tests Comparison table.

Performed

24 hours, 7 days a week

Methodology

Competitive immunoassay format with direct chemiluminescent technology

Synonyms

  • Estradiol, 17b

CPT Codes

82670

Reference Interval

Effective May 11, 2021
Female  
Follicular phase 20-144 pg/mL
Mid Cycle phase 64-357 pg/mL
Luteal Phase 56-214 pg/mL
Post-Menopausal  < 32 pg/mL

MALE:  <40 pg/mL

Interpretive Data

This immunoassay is not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (e.g., aromatase inhibitor) therapy. The preferred estradiol test in these cases is Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy) (ARUP test code 0093247).

No reference intervals have been established for prepubertal females or for cisgender males. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0070045

CPT Codes

82670

Performing Lab

Performed at Southwest General
Collection

Collect

Gold top tube - Serum

Specimen Preparation

Allow specimen to clot completely before centrifugation.  Keep capped at all times.

Specimen Type

Blood

Unacceptable Conditions

Grossly hemolyzed or lipemic specimens.

Stability (from collection to initiation)

After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months

Performed

24 hours, 7 days a week
Ordering

Ordering Recommendations

Use this immunoassay to measure estradiol in adult premenopausal cisgender females and individuals on estrogen hormone therapies. Not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (eg, aromatase inhibitor) therapy.   Not recommended in the evaluation of estradiol status for individuals with protein-binding abnormalities or individuals on hormonal contraception.  To compare this test to other estrogen tests, refer to the ARUP Estrogen Tests Comparison table.

Performed

24 hours, 7 days a week

Methodology

Competitive immunoassay format with direct chemiluminescent technology

Synonyms

  • Estradiol, 17b

CPT Codes

82670
Result Interpretation

Reference Interval

Effective May 11, 2021
Female  
Follicular phase 20-144 pg/mL
Mid Cycle phase 64-357 pg/mL
Luteal Phase 56-214 pg/mL
Post-Menopausal  < 32 pg/mL

MALE:  <40 pg/mL

Interpretive Data

This immunoassay is not recommended when low estradiol concentrations, such as those found in children, cisgender males, and postmenopausal females, are expected, or for monitoring antiestrogen (e.g., aromatase inhibitor) therapy. The preferred estradiol test in these cases is Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy) (ARUP test code 0093247).

No reference intervals have been established for prepubertal females or for cisgender males. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0070045

Administrative

CPT Codes

82670

Performing Lab

Performed at Southwest General