Available Stat

No

Performing Lab

China Basin Chemistry

Performed

Test available on day shift, 7 days per week.

Methodology

Chemiluminescent Microparticle Immunoassay (Abbott Architect i1000)

Reported

1-3 days

Additional Information

The Architect cortisol assay is highly specific for cortisol and correlates well with mass spectrometry methods (Dodd AJ et al. Annals of Clinical Biochemistry 2014).

The specificity of the ARCHITECT Cortisol assay was determined by studying the cross-reactivity of compounds whose chemical structure or concurrent usage may potentially interfere with the ARCHITECT Cortisol assay. Specificity of the assay was determined by spiking each compound into human serum specimens with cortisol levels of 11.4 and 12.0 µg/dL. Cross reactivity results with other steroids are listed below.
Compound Conc (ug/dL) % Cross-Reactivity
Aldosterone 1000 0.0
Beclomethasone 1000 0.0
Budesonide 1000 0.0
Canrenone 1000 0.1
Corticosterone 1000 0.9
Cortisol 21-glucuronide 1000 0.2
Cortisone 1000 2.7
B-Cortol 1000 0.0
B-Cortolone 1000 0.0
11-Deoxycorticosterone 100 0.0
11-Deoxycortisol 100 1.9
Dexamethasone 1000 0.0
DHEA 1000 0.0
DHEA-S 1000 0.0
B-Estradiol 1000 0.0
Estriol 1000 0.0
Estrone 1000 0.0
Fludrocortisone 100 36.6
Fluticasone Propionate 1000 0.0
6B-Hydroxycortisol 1000 0.2
17a-Hydroxypregnenolone 1000 0.1
11B-Hydroxyprogesterone 1000 0.2
17-Hydroxyprogesterone 1000 0.6
Medroxyprogesterone Acetate 1000 0.0
6-Methylprednisolone 1000 0.1
Mometasone 1000 0.0
Prednisolone 100 12.3
Prednisone 1000 0.0
Pregnanetriol 1000 0.0
Pregnenolone 1000 0.0
Progesterone 1000 0.0
B-Sitosterol 1000 0.0
Spironolactone 1000 0.0
Testosterone 1000 0.0


Synonyms

  • Compound F
  • 11-hydroxycorticosteroids
  • 11-hydroxycorticoids
  • 11-OH steroids
  • 11-OH corticosteroids
  • Cosyntropin provocative testing

Sample Type

Serum

Collect

Preferred: Gold top or Red top; Acceptable: Green Top (Sodium/Lithium Heparin)

Amount to Collect

1 mL blood

Preferred Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Remarks

A morning sample is usually recommended.

Unacceptable Conditions

Samples will not be rejected based on time of collection.

Test Code

CORT

Test Group

Cortisol

Performing Lab

China Basin Chemistry

Specimen Preparation

Refrigerate

Preferred Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Unacceptable Conditions

Samples will not be rejected based on time of collection.

Units

µg/dL

Reference Interval

Adult Reference Range (ug/dL)
AM (before 10am): 4 - 19 
PM (after 5pm): 3 - 17 

Reference range adopted from vendor performed studies and verified by running lab personnel.

Pediatric Reference Range (ug/dL) 
2 - 14 days: 0.5 - 12
15 days - < 1 year: 0.5 - 17
1 year - < 9 years: 2 - 11
9 - < 14 years: 2 - 13
14 - < 17 years: 3 - 16
17 years - < 19 years: 4 - 18

Pediatric reference ranges adopted from CALIPER Pediatric Reference Interval study performed on random samples using the Abbott Architect i2000 assay. Morning samples gave results approximately 10% higher than afternoon samples.

Bailey et al. Clinical Chemistry 59:9 1393-1405 (2013)

Additional Information

The Architect cortisol assay is highly specific for cortisol and correlates well with mass spectrometry methods (Dodd AJ et al. Annals of Clinical Biochemistry 2014).

The specificity of the ARCHITECT Cortisol assay was determined by studying the cross-reactivity of compounds whose chemical structure or concurrent usage may potentially interfere with the ARCHITECT Cortisol assay. Specificity of the assay was determined by spiking each compound into human serum specimens with cortisol levels of 11.4 and 12.0 µg/dL. Cross reactivity results with other steroids are listed below.
Compound Conc (ug/dL) % Cross-Reactivity
Aldosterone 1000 0.0
Beclomethasone 1000 0.0
Budesonide 1000 0.0
Canrenone 1000 0.1
Corticosterone 1000 0.9
Cortisol 21-glucuronide 1000 0.2
Cortisone 1000 2.7
B-Cortol 1000 0.0
B-Cortolone 1000 0.0
11-Deoxycorticosterone 100 0.0
11-Deoxycortisol 100 1.9
Dexamethasone 1000 0.0
DHEA 1000 0.0
DHEA-S 1000 0.0
B-Estradiol 1000 0.0
Estriol 1000 0.0
Estrone 1000 0.0
Fludrocortisone 100 36.6
Fluticasone Propionate 1000 0.0
6B-Hydroxycortisol 1000 0.2
17a-Hydroxypregnenolone 1000 0.1
11B-Hydroxyprogesterone 1000 0.2
17-Hydroxyprogesterone 1000 0.6
Medroxyprogesterone Acetate 1000 0.0
6-Methylprednisolone 1000 0.1
Mometasone 1000 0.0
Prednisolone 100 12.3
Prednisone 1000 0.0
Pregnanetriol 1000 0.0
Pregnenolone 1000 0.0
Progesterone 1000 0.0
B-Sitosterol 1000 0.0
Spironolactone 1000 0.0
Testosterone 1000 0.0


CPT Codes

82533

LOINC Codes

2143-6

Available Stat

No

Test Code

CORT

Test Group

Cortisol

Performing Lab

China Basin Chemistry

Performed

Test available on day shift, 7 days per week.

Methodology

Chemiluminescent Microparticle Immunoassay (Abbott Architect i1000)

Remarks

A morning sample is usually recommended.

Collect

Preferred: Gold top or Red top; Acceptable: Green Top (Sodium/Lithium Heparin)

Amount to Collect

1 mL blood

Sample Type

Serum

Preferred Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Unacceptable Conditions

Samples will not be rejected based on time of collection.

Specimen Preparation

Refrigerate

Units

µg/dL

Reference Interval

Adult Reference Range (ug/dL)
AM (before 10am): 4 - 19 
PM (after 5pm): 3 - 17 

Reference range adopted from vendor performed studies and verified by running lab personnel.

Pediatric Reference Range (ug/dL) 
2 - 14 days: 0.5 - 12
15 days - < 1 year: 0.5 - 17
1 year - < 9 years: 2 - 11
9 - < 14 years: 2 - 13
14 - < 17 years: 3 - 16
17 years - < 19 years: 4 - 18

Pediatric reference ranges adopted from CALIPER Pediatric Reference Interval study performed on random samples using the Abbott Architect i2000 assay. Morning samples gave results approximately 10% higher than afternoon samples.

Bailey et al. Clinical Chemistry 59:9 1393-1405 (2013)

Synonyms

  • Compound F
  • 11-hydroxycorticosteroids
  • 11-hydroxycorticoids
  • 11-OH steroids
  • 11-OH corticosteroids
  • Cosyntropin provocative testing

Reported

1-3 days

Additional Information

The Architect cortisol assay is highly specific for cortisol and correlates well with mass spectrometry methods (Dodd AJ et al. Annals of Clinical Biochemistry 2014).

The specificity of the ARCHITECT Cortisol assay was determined by studying the cross-reactivity of compounds whose chemical structure or concurrent usage may potentially interfere with the ARCHITECT Cortisol assay. Specificity of the assay was determined by spiking each compound into human serum specimens with cortisol levels of 11.4 and 12.0 µg/dL. Cross reactivity results with other steroids are listed below.
Compound Conc (ug/dL) % Cross-Reactivity
Aldosterone 1000 0.0
Beclomethasone 1000 0.0
Budesonide 1000 0.0
Canrenone 1000 0.1
Corticosterone 1000 0.9
Cortisol 21-glucuronide 1000 0.2
Cortisone 1000 2.7
B-Cortol 1000 0.0
B-Cortolone 1000 0.0
11-Deoxycorticosterone 100 0.0
11-Deoxycortisol 100 1.9
Dexamethasone 1000 0.0
DHEA 1000 0.0
DHEA-S 1000 0.0
B-Estradiol 1000 0.0
Estriol 1000 0.0
Estrone 1000 0.0
Fludrocortisone 100 36.6
Fluticasone Propionate 1000 0.0
6B-Hydroxycortisol 1000 0.2
17a-Hydroxypregnenolone 1000 0.1
11B-Hydroxyprogesterone 1000 0.2
17-Hydroxyprogesterone 1000 0.6
Medroxyprogesterone Acetate 1000 0.0
6-Methylprednisolone 1000 0.1
Mometasone 1000 0.0
Prednisolone 100 12.3
Prednisone 1000 0.0
Pregnanetriol 1000 0.0
Pregnenolone 1000 0.0
Progesterone 1000 0.0
B-Sitosterol 1000 0.0
Spironolactone 1000 0.0
Testosterone 1000 0.0


CPT Codes

82533

LOINC Codes

2143-6
Ordering

Available Stat

No

Performing Lab

China Basin Chemistry

Performed

Test available on day shift, 7 days per week.

Methodology

Chemiluminescent Microparticle Immunoassay (Abbott Architect i1000)

Reported

1-3 days

Additional Information

The Architect cortisol assay is highly specific for cortisol and correlates well with mass spectrometry methods (Dodd AJ et al. Annals of Clinical Biochemistry 2014).

The specificity of the ARCHITECT Cortisol assay was determined by studying the cross-reactivity of compounds whose chemical structure or concurrent usage may potentially interfere with the ARCHITECT Cortisol assay. Specificity of the assay was determined by spiking each compound into human serum specimens with cortisol levels of 11.4 and 12.0 µg/dL. Cross reactivity results with other steroids are listed below.
Compound Conc (ug/dL) % Cross-Reactivity
Aldosterone 1000 0.0
Beclomethasone 1000 0.0
Budesonide 1000 0.0
Canrenone 1000 0.1
Corticosterone 1000 0.9
Cortisol 21-glucuronide 1000 0.2
Cortisone 1000 2.7
B-Cortol 1000 0.0
B-Cortolone 1000 0.0
11-Deoxycorticosterone 100 0.0
11-Deoxycortisol 100 1.9
Dexamethasone 1000 0.0
DHEA 1000 0.0
DHEA-S 1000 0.0
B-Estradiol 1000 0.0
Estriol 1000 0.0
Estrone 1000 0.0
Fludrocortisone 100 36.6
Fluticasone Propionate 1000 0.0
6B-Hydroxycortisol 1000 0.2
17a-Hydroxypregnenolone 1000 0.1
11B-Hydroxyprogesterone 1000 0.2
17-Hydroxyprogesterone 1000 0.6
Medroxyprogesterone Acetate 1000 0.0
6-Methylprednisolone 1000 0.1
Mometasone 1000 0.0
Prednisolone 100 12.3
Prednisone 1000 0.0
Pregnanetriol 1000 0.0
Pregnenolone 1000 0.0
Progesterone 1000 0.0
B-Sitosterol 1000 0.0
Spironolactone 1000 0.0
Testosterone 1000 0.0


Synonyms

  • Compound F
  • 11-hydroxycorticosteroids
  • 11-hydroxycorticoids
  • 11-OH steroids
  • 11-OH corticosteroids
  • Cosyntropin provocative testing
Collection

Sample Type

Serum

Collect

Preferred: Gold top or Red top; Acceptable: Green Top (Sodium/Lithium Heparin)

Amount to Collect

1 mL blood

Preferred Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Remarks

A morning sample is usually recommended.

Unacceptable Conditions

Samples will not be rejected based on time of collection.
Processing

Test Code

CORT

Test Group

Cortisol

Performing Lab

China Basin Chemistry

Specimen Preparation

Refrigerate

Preferred Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Unacceptable Conditions

Samples will not be rejected based on time of collection.
Result Interpretation

Units

µg/dL

Reference Interval

Adult Reference Range (ug/dL)
AM (before 10am): 4 - 19 
PM (after 5pm): 3 - 17 

Reference range adopted from vendor performed studies and verified by running lab personnel.

Pediatric Reference Range (ug/dL) 
2 - 14 days: 0.5 - 12
15 days - < 1 year: 0.5 - 17
1 year - < 9 years: 2 - 11
9 - < 14 years: 2 - 13
14 - < 17 years: 3 - 16
17 years - < 19 years: 4 - 18

Pediatric reference ranges adopted from CALIPER Pediatric Reference Interval study performed on random samples using the Abbott Architect i2000 assay. Morning samples gave results approximately 10% higher than afternoon samples.

Bailey et al. Clinical Chemistry 59:9 1393-1405 (2013)

Additional Information

The Architect cortisol assay is highly specific for cortisol and correlates well with mass spectrometry methods (Dodd AJ et al. Annals of Clinical Biochemistry 2014).

The specificity of the ARCHITECT Cortisol assay was determined by studying the cross-reactivity of compounds whose chemical structure or concurrent usage may potentially interfere with the ARCHITECT Cortisol assay. Specificity of the assay was determined by spiking each compound into human serum specimens with cortisol levels of 11.4 and 12.0 µg/dL. Cross reactivity results with other steroids are listed below.
Compound Conc (ug/dL) % Cross-Reactivity
Aldosterone 1000 0.0
Beclomethasone 1000 0.0
Budesonide 1000 0.0
Canrenone 1000 0.1
Corticosterone 1000 0.9
Cortisol 21-glucuronide 1000 0.2
Cortisone 1000 2.7
B-Cortol 1000 0.0
B-Cortolone 1000 0.0
11-Deoxycorticosterone 100 0.0
11-Deoxycortisol 100 1.9
Dexamethasone 1000 0.0
DHEA 1000 0.0
DHEA-S 1000 0.0
B-Estradiol 1000 0.0
Estriol 1000 0.0
Estrone 1000 0.0
Fludrocortisone 100 36.6
Fluticasone Propionate 1000 0.0
6B-Hydroxycortisol 1000 0.2
17a-Hydroxypregnenolone 1000 0.1
11B-Hydroxyprogesterone 1000 0.2
17-Hydroxyprogesterone 1000 0.6
Medroxyprogesterone Acetate 1000 0.0
6-Methylprednisolone 1000 0.1
Mometasone 1000 0.0
Prednisolone 100 12.3
Prednisone 1000 0.0
Pregnanetriol 1000 0.0
Pregnenolone 1000 0.0
Progesterone 1000 0.0
B-Sitosterol 1000 0.0
Spironolactone 1000 0.0
Testosterone 1000 0.0


Administrative

CPT Codes

82533

LOINC Codes

2143-6
Complete View

Available Stat

No

Test Code

CORT

Test Group

Cortisol

Performing Lab

China Basin Chemistry

Performed

Test available on day shift, 7 days per week.

Methodology

Chemiluminescent Microparticle Immunoassay (Abbott Architect i1000)

Remarks

A morning sample is usually recommended.

Collect

Preferred: Gold top or Red top; Acceptable: Green Top (Sodium/Lithium Heparin)

Amount to Collect

1 mL blood

Sample Type

Serum

Preferred Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Unacceptable Conditions

Samples will not be rejected based on time of collection.

Specimen Preparation

Refrigerate

Units

µg/dL

Reference Interval

Adult Reference Range (ug/dL)
AM (before 10am): 4 - 19 
PM (after 5pm): 3 - 17 

Reference range adopted from vendor performed studies and verified by running lab personnel.

Pediatric Reference Range (ug/dL) 
2 - 14 days: 0.5 - 12
15 days - < 1 year: 0.5 - 17
1 year - < 9 years: 2 - 11
9 - < 14 years: 2 - 13
14 - < 17 years: 3 - 16
17 years - < 19 years: 4 - 18

Pediatric reference ranges adopted from CALIPER Pediatric Reference Interval study performed on random samples using the Abbott Architect i2000 assay. Morning samples gave results approximately 10% higher than afternoon samples.

Bailey et al. Clinical Chemistry 59:9 1393-1405 (2013)

Synonyms

  • Compound F
  • 11-hydroxycorticosteroids
  • 11-hydroxycorticoids
  • 11-OH steroids
  • 11-OH corticosteroids
  • Cosyntropin provocative testing

Reported

1-3 days

Additional Information

The Architect cortisol assay is highly specific for cortisol and correlates well with mass spectrometry methods (Dodd AJ et al. Annals of Clinical Biochemistry 2014).

The specificity of the ARCHITECT Cortisol assay was determined by studying the cross-reactivity of compounds whose chemical structure or concurrent usage may potentially interfere with the ARCHITECT Cortisol assay. Specificity of the assay was determined by spiking each compound into human serum specimens with cortisol levels of 11.4 and 12.0 µg/dL. Cross reactivity results with other steroids are listed below.
Compound Conc (ug/dL) % Cross-Reactivity
Aldosterone 1000 0.0
Beclomethasone 1000 0.0
Budesonide 1000 0.0
Canrenone 1000 0.1
Corticosterone 1000 0.9
Cortisol 21-glucuronide 1000 0.2
Cortisone 1000 2.7
B-Cortol 1000 0.0
B-Cortolone 1000 0.0
11-Deoxycorticosterone 100 0.0
11-Deoxycortisol 100 1.9
Dexamethasone 1000 0.0
DHEA 1000 0.0
DHEA-S 1000 0.0
B-Estradiol 1000 0.0
Estriol 1000 0.0
Estrone 1000 0.0
Fludrocortisone 100 36.6
Fluticasone Propionate 1000 0.0
6B-Hydroxycortisol 1000 0.2
17a-Hydroxypregnenolone 1000 0.1
11B-Hydroxyprogesterone 1000 0.2
17-Hydroxyprogesterone 1000 0.6
Medroxyprogesterone Acetate 1000 0.0
6-Methylprednisolone 1000 0.1
Mometasone 1000 0.0
Prednisolone 100 12.3
Prednisone 1000 0.0
Pregnanetriol 1000 0.0
Pregnenolone 1000 0.0
Progesterone 1000 0.0
B-Sitosterol 1000 0.0
Spironolactone 1000 0.0
Testosterone 1000 0.0


CPT Codes

82533

LOINC Codes

2143-6

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