Available Stat

Yes

Performing Lab

Parnassus, Mission Bay & Mt. Zion Chemistry
Berkeley Outpatient Center
Peninsula Outpatient Center
Saint Francis Chemistry
Saint Marys Chemistry

Performed

Parnassus, Mission Bay & Mt. Zion Chemistry: Test available 24 hours per day 7 days per week
Berkeley Outpatient Center (Mon-Fri 0800-1630)
Peninsula Outpatient Center (Mon-Fri 0800-1630)
Saint Francis Chemistry: Test available 24 hours per day 7 days per week
Saint Marys Chemistry: Test available 24 hours per day 7 days per week

Methodology

Parnassus, Mission Bay, Mt. Zion:  Enzymatic assay on Abbott Architect

Saint Francis and St Mary’s: Jaffe kinetic alkaline picrate on Abbott Architect

Berkeley Outpatient Center and Peninsula Outpatient Center: Enzymatic assay on Roche cobas c311

Reported

STAT 1 hour, Routine 4 hours

Additional Information

For Parnassus, Mission Bay and Mount Zion only:
In patients receiving catecholamine infusions (e.g., dopamine, dobutamine, norepinephrine, or epinephrine), falsely low serum/plasma creatinine results can occur with this enzymatic creatinine assay when blood is sampled through an indwelling catheter.  In these cases, accurate measurements of creatinine can be obtained by testing blood samples obtained by venipuncture instead of through an indwelling catheter (based on in-house studies and Saenger AK, Clinical Chemistry 2009, vol 55:9 1732–1736).

To convert mg/dL to µmol/L (SI units) multiply by 88.4.

For all creatinine assays:
Estimated GFR (eGFRcr) is reported with serum creatinine results in adults and is determined using the CKD-EPI (2021) equation without race coefficient (NKF-ASN recommendations). Creatinine results traceable to isotope dilution mass spec IDMS calibration. Note that the estimated GFR result is not reliable in certain groups including severely ill patients. Estimates of eGFR with the CKD-EPI (2021) equation like other equations may also be less accurate in specific ethnic groups (eg, Asians in the United States), pregnant women, and those with unusual muscle mass, body habitus, and weight (eg, morbid obesity, amputees). Reference: Assessment of Kidney Function. WWW.UpToDate.com

CKD-EPI (2021) equation without race coefficient:

eGFRcr = 142 x [min (sCR/kappa,1)alpha  x max(sCR/kappa, 1)-1.200] x 0.9938AGE x 1.012 [if female] 

Where:
-    sCR is serum creatinine in mg/dL
-    kappa is 0.7 for females and 0.9 for males
-    alpha is -0.241 for females and -0.302 for males
-    min indicates the minimum of sCR/kappa or 1, and max indicates the maximum of sCR/kappa or 1
- units are in mL/min/1.73 m2  body surface area


An eGFRcr will be calculated and reported with each plasma/serum creatinine result.

According to the National Kidney Disease Education Program, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Isotope Dilution Mass Spectrometry (IDMS)-traceable Schwartz equation http://www.nkdep.nih.gov/lab-evaluation/gfr-calculators/children-conventional-unit.shtml

Bedside IDMS-traceable Schwartz Equation for Children

GFR (mL/min/1.73 m2) = (0.41 x Height in cm) / Creatinine in mg/dL)

Synonyms

  • GFR
  • eGFRcr
  • glomerular filtration rate
  • CRG

Sample Type

Plasma or serum

Collect

Preferred:  Light Green Top
Acceptable:  Gold Top or Red Top

Amount to Collect

1 mL blood

Preferred Volume

0.5 mL plasma or serum

Minimum Volume

0.2 mL plasma or serum

Stability (from collection to initiation)

Room temperature:  7 days
Refrigerated:  7 days
Frozen at -20C:  3 months
 

Test Code

CRG

Test Group

Creatinine

Performing Lab

Parnassus, Mission Bay & Mt. Zion Chemistry
Berkeley Outpatient Center
Peninsula Outpatient Center
Saint Francis Chemistry
Saint Marys Chemistry

Preferred Volume

0.5 mL plasma or serum

Minimum Volume

0.2 mL plasma or serum

Stability (from collection to initiation)

Room temperature:  7 days
Refrigerated:  7 days
Frozen at -20C:  3 months
 

Units

Creatinine: mg/dL
eGFRcr:  mL/min/1.73 m2  body surface area

Reference Interval

Parnassus, Mission Bay, Mt. Zion, Saint Francis, & Saint Marys Chemistry
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
0 to 14 days0.32-0.920.32-0.92
15 days to < 2 years0.10-0.320.10-0.32
2 to < 5 years0.20-0.430.20-0.43
5 to < 12 years0.31-0.610.31-0.61
12 to < 15 years0.45-0.810.45-0.81
15 to < 19 years0.62-1.080.49-0.84
>= 19 years0.73-1.240.55-1.02

eGFRcr:
≥ 18 years> 59 mL/min/1.73 m2
< 18 yearsNot calculated (See Addtl. Info.)
1. Pediatric ranges adopted from Canadian Laboratory Initiative on Reference Interval Database (CALIPER) study, https://caliper.research.sickkids.ca/#/

2. UCSF Clinical Labs at Parnassus, Mission Bay, and Mount Zion verified the adult reference range stated in the Abbott Creatinine, Enzymatic package insert (June 2016) by running 20 male and 20 female lab volunteers.

On September 10, 2020, the upper limit of the Abbott creatinine reference range in males was modified from 1.18 to 1.24 mg/dL to align with the reference range previously established in the UCSF Clinical Laboratories with the Beckman creatinine method.




Berkeley Outpatient Center and Peninsula Outpatient Center
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
≥ 19 years0.69-1.370.47-1.10

eGFRcr:
AgeeGFRcr
≥ 18 years> 59 mL/min/1.73 m2

Adult reference intervals adopted from the NHANES 2011-2012 survey that determined reference intervals in a multi-ethnic sample of males and females in the USA using an IDMS traceable creatinine assay.   The reference intervals were verified by testing 20 male and 20 female normal volunteers from UCSF Clinical Laboratories.  Lim E, et al, Racial/Ethnic-Specific Reference Intervals for Common Laboratory Tests: A Comparison among Asians, Blacks, Hispanics, and White.  Hawaii J Med Public Health, 2015;74:302-310

Additional Information

For Parnassus, Mission Bay and Mount Zion only:
In patients receiving catecholamine infusions (e.g., dopamine, dobutamine, norepinephrine, or epinephrine), falsely low serum/plasma creatinine results can occur with this enzymatic creatinine assay when blood is sampled through an indwelling catheter.  In these cases, accurate measurements of creatinine can be obtained by testing blood samples obtained by venipuncture instead of through an indwelling catheter (based on in-house studies and Saenger AK, Clinical Chemistry 2009, vol 55:9 1732–1736).

To convert mg/dL to µmol/L (SI units) multiply by 88.4.

For all creatinine assays:
Estimated GFR (eGFRcr) is reported with serum creatinine results in adults and is determined using the CKD-EPI (2021) equation without race coefficient (NKF-ASN recommendations). Creatinine results traceable to isotope dilution mass spec IDMS calibration. Note that the estimated GFR result is not reliable in certain groups including severely ill patients. Estimates of eGFR with the CKD-EPI (2021) equation like other equations may also be less accurate in specific ethnic groups (eg, Asians in the United States), pregnant women, and those with unusual muscle mass, body habitus, and weight (eg, morbid obesity, amputees). Reference: Assessment of Kidney Function. WWW.UpToDate.com

CKD-EPI (2021) equation without race coefficient:

eGFRcr = 142 x [min (sCR/kappa,1)alpha  x max(sCR/kappa, 1)-1.200] x 0.9938AGE x 1.012 [if female] 

Where:
-    sCR is serum creatinine in mg/dL
-    kappa is 0.7 for females and 0.9 for males
-    alpha is -0.241 for females and -0.302 for males
-    min indicates the minimum of sCR/kappa or 1, and max indicates the maximum of sCR/kappa or 1
- units are in mL/min/1.73 m2  body surface area


An eGFRcr will be calculated and reported with each plasma/serum creatinine result.

According to the National Kidney Disease Education Program, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Isotope Dilution Mass Spectrometry (IDMS)-traceable Schwartz equation http://www.nkdep.nih.gov/lab-evaluation/gfr-calculators/children-conventional-unit.shtml

Bedside IDMS-traceable Schwartz Equation for Children

GFR (mL/min/1.73 m2) = (0.41 x Height in cm) / Creatinine in mg/dL)

CPT Codes

82565

LOINC Codes

2160-0

Available Stat

Yes

Test Code

CRG

Test Group

Creatinine

Performing Lab

Parnassus, Mission Bay & Mt. Zion Chemistry
Berkeley Outpatient Center
Peninsula Outpatient Center
Saint Francis Chemistry
Saint Marys Chemistry

Performed

Parnassus, Mission Bay & Mt. Zion Chemistry: Test available 24 hours per day 7 days per week
Berkeley Outpatient Center (Mon-Fri 0800-1630)
Peninsula Outpatient Center (Mon-Fri 0800-1630)
Saint Francis Chemistry: Test available 24 hours per day 7 days per week
Saint Marys Chemistry: Test available 24 hours per day 7 days per week

Methodology

Parnassus, Mission Bay, Mt. Zion:  Enzymatic assay on Abbott Architect

Saint Francis and St Mary’s: Jaffe kinetic alkaline picrate on Abbott Architect

Berkeley Outpatient Center and Peninsula Outpatient Center: Enzymatic assay on Roche cobas c311

Collect

Preferred:  Light Green Top
Acceptable:  Gold Top or Red Top

Amount to Collect

1 mL blood

Sample Type

Plasma or serum

Preferred Volume

0.5 mL plasma or serum

Minimum Volume

0.2 mL plasma or serum

Units

Creatinine: mg/dL
eGFRcr:  mL/min/1.73 m2  body surface area

Reference Interval

Parnassus, Mission Bay, Mt. Zion, Saint Francis, & Saint Marys Chemistry
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
0 to 14 days0.32-0.920.32-0.92
15 days to < 2 years0.10-0.320.10-0.32
2 to < 5 years0.20-0.430.20-0.43
5 to < 12 years0.31-0.610.31-0.61
12 to < 15 years0.45-0.810.45-0.81
15 to < 19 years0.62-1.080.49-0.84
>= 19 years0.73-1.240.55-1.02

eGFRcr:
≥ 18 years> 59 mL/min/1.73 m2
< 18 yearsNot calculated (See Addtl. Info.)
1. Pediatric ranges adopted from Canadian Laboratory Initiative on Reference Interval Database (CALIPER) study, https://caliper.research.sickkids.ca/#/

2. UCSF Clinical Labs at Parnassus, Mission Bay, and Mount Zion verified the adult reference range stated in the Abbott Creatinine, Enzymatic package insert (June 2016) by running 20 male and 20 female lab volunteers.

On September 10, 2020, the upper limit of the Abbott creatinine reference range in males was modified from 1.18 to 1.24 mg/dL to align with the reference range previously established in the UCSF Clinical Laboratories with the Beckman creatinine method.




Berkeley Outpatient Center and Peninsula Outpatient Center
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
≥ 19 years0.69-1.370.47-1.10

eGFRcr:
AgeeGFRcr
≥ 18 years> 59 mL/min/1.73 m2

Adult reference intervals adopted from the NHANES 2011-2012 survey that determined reference intervals in a multi-ethnic sample of males and females in the USA using an IDMS traceable creatinine assay.   The reference intervals were verified by testing 20 male and 20 female normal volunteers from UCSF Clinical Laboratories.  Lim E, et al, Racial/Ethnic-Specific Reference Intervals for Common Laboratory Tests: A Comparison among Asians, Blacks, Hispanics, and White.  Hawaii J Med Public Health, 2015;74:302-310

Synonyms

  • GFR
  • eGFRcr
  • glomerular filtration rate
  • CRG

Stability (from collection to initiation)

Room temperature:  7 days
Refrigerated:  7 days
Frozen at -20C:  3 months
 

Reported

STAT 1 hour, Routine 4 hours

Additional Information

For Parnassus, Mission Bay and Mount Zion only:
In patients receiving catecholamine infusions (e.g., dopamine, dobutamine, norepinephrine, or epinephrine), falsely low serum/plasma creatinine results can occur with this enzymatic creatinine assay when blood is sampled through an indwelling catheter.  In these cases, accurate measurements of creatinine can be obtained by testing blood samples obtained by venipuncture instead of through an indwelling catheter (based on in-house studies and Saenger AK, Clinical Chemistry 2009, vol 55:9 1732–1736).

To convert mg/dL to µmol/L (SI units) multiply by 88.4.

For all creatinine assays:
Estimated GFR (eGFRcr) is reported with serum creatinine results in adults and is determined using the CKD-EPI (2021) equation without race coefficient (NKF-ASN recommendations). Creatinine results traceable to isotope dilution mass spec IDMS calibration. Note that the estimated GFR result is not reliable in certain groups including severely ill patients. Estimates of eGFR with the CKD-EPI (2021) equation like other equations may also be less accurate in specific ethnic groups (eg, Asians in the United States), pregnant women, and those with unusual muscle mass, body habitus, and weight (eg, morbid obesity, amputees). Reference: Assessment of Kidney Function. WWW.UpToDate.com

CKD-EPI (2021) equation without race coefficient:

eGFRcr = 142 x [min (sCR/kappa,1)alpha  x max(sCR/kappa, 1)-1.200] x 0.9938AGE x 1.012 [if female] 

Where:
-    sCR is serum creatinine in mg/dL
-    kappa is 0.7 for females and 0.9 for males
-    alpha is -0.241 for females and -0.302 for males
-    min indicates the minimum of sCR/kappa or 1, and max indicates the maximum of sCR/kappa or 1
- units are in mL/min/1.73 m2  body surface area


An eGFRcr will be calculated and reported with each plasma/serum creatinine result.

According to the National Kidney Disease Education Program, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Isotope Dilution Mass Spectrometry (IDMS)-traceable Schwartz equation http://www.nkdep.nih.gov/lab-evaluation/gfr-calculators/children-conventional-unit.shtml

Bedside IDMS-traceable Schwartz Equation for Children

GFR (mL/min/1.73 m2) = (0.41 x Height in cm) / Creatinine in mg/dL)

CPT Codes

82565

LOINC Codes

2160-0
Ordering

Available Stat

Yes

Performing Lab

Parnassus, Mission Bay & Mt. Zion Chemistry
Berkeley Outpatient Center
Peninsula Outpatient Center
Saint Francis Chemistry
Saint Marys Chemistry

Performed

Parnassus, Mission Bay & Mt. Zion Chemistry: Test available 24 hours per day 7 days per week
Berkeley Outpatient Center (Mon-Fri 0800-1630)
Peninsula Outpatient Center (Mon-Fri 0800-1630)
Saint Francis Chemistry: Test available 24 hours per day 7 days per week
Saint Marys Chemistry: Test available 24 hours per day 7 days per week

Methodology

Parnassus, Mission Bay, Mt. Zion:  Enzymatic assay on Abbott Architect

Saint Francis and St Mary’s: Jaffe kinetic alkaline picrate on Abbott Architect

Berkeley Outpatient Center and Peninsula Outpatient Center: Enzymatic assay on Roche cobas c311

Reported

STAT 1 hour, Routine 4 hours

Additional Information

For Parnassus, Mission Bay and Mount Zion only:
In patients receiving catecholamine infusions (e.g., dopamine, dobutamine, norepinephrine, or epinephrine), falsely low serum/plasma creatinine results can occur with this enzymatic creatinine assay when blood is sampled through an indwelling catheter.  In these cases, accurate measurements of creatinine can be obtained by testing blood samples obtained by venipuncture instead of through an indwelling catheter (based on in-house studies and Saenger AK, Clinical Chemistry 2009, vol 55:9 1732–1736).

To convert mg/dL to µmol/L (SI units) multiply by 88.4.

For all creatinine assays:
Estimated GFR (eGFRcr) is reported with serum creatinine results in adults and is determined using the CKD-EPI (2021) equation without race coefficient (NKF-ASN recommendations). Creatinine results traceable to isotope dilution mass spec IDMS calibration. Note that the estimated GFR result is not reliable in certain groups including severely ill patients. Estimates of eGFR with the CKD-EPI (2021) equation like other equations may also be less accurate in specific ethnic groups (eg, Asians in the United States), pregnant women, and those with unusual muscle mass, body habitus, and weight (eg, morbid obesity, amputees). Reference: Assessment of Kidney Function. WWW.UpToDate.com

CKD-EPI (2021) equation without race coefficient:

eGFRcr = 142 x [min (sCR/kappa,1)alpha  x max(sCR/kappa, 1)-1.200] x 0.9938AGE x 1.012 [if female] 

Where:
-    sCR is serum creatinine in mg/dL
-    kappa is 0.7 for females and 0.9 for males
-    alpha is -0.241 for females and -0.302 for males
-    min indicates the minimum of sCR/kappa or 1, and max indicates the maximum of sCR/kappa or 1
- units are in mL/min/1.73 m2  body surface area


An eGFRcr will be calculated and reported with each plasma/serum creatinine result.

According to the National Kidney Disease Education Program, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Isotope Dilution Mass Spectrometry (IDMS)-traceable Schwartz equation http://www.nkdep.nih.gov/lab-evaluation/gfr-calculators/children-conventional-unit.shtml

Bedside IDMS-traceable Schwartz Equation for Children

GFR (mL/min/1.73 m2) = (0.41 x Height in cm) / Creatinine in mg/dL)

Synonyms

  • GFR
  • eGFRcr
  • glomerular filtration rate
  • CRG
Collection

Sample Type

Plasma or serum

Collect

Preferred:  Light Green Top
Acceptable:  Gold Top or Red Top

Amount to Collect

1 mL blood

Preferred Volume

0.5 mL plasma or serum

Minimum Volume

0.2 mL plasma or serum

Stability (from collection to initiation)

Room temperature:  7 days
Refrigerated:  7 days
Frozen at -20C:  3 months
 
Processing

Test Code

CRG

Test Group

Creatinine

Performing Lab

Parnassus, Mission Bay & Mt. Zion Chemistry
Berkeley Outpatient Center
Peninsula Outpatient Center
Saint Francis Chemistry
Saint Marys Chemistry

Preferred Volume

0.5 mL plasma or serum

Minimum Volume

0.2 mL plasma or serum

Stability (from collection to initiation)

Room temperature:  7 days
Refrigerated:  7 days
Frozen at -20C:  3 months
 
Result Interpretation

Units

Creatinine: mg/dL
eGFRcr:  mL/min/1.73 m2  body surface area

Reference Interval

Parnassus, Mission Bay, Mt. Zion, Saint Francis, & Saint Marys Chemistry
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
0 to 14 days0.32-0.920.32-0.92
15 days to < 2 years0.10-0.320.10-0.32
2 to < 5 years0.20-0.430.20-0.43
5 to < 12 years0.31-0.610.31-0.61
12 to < 15 years0.45-0.810.45-0.81
15 to < 19 years0.62-1.080.49-0.84
>= 19 years0.73-1.240.55-1.02

eGFRcr:
≥ 18 years> 59 mL/min/1.73 m2
< 18 yearsNot calculated (See Addtl. Info.)
1. Pediatric ranges adopted from Canadian Laboratory Initiative on Reference Interval Database (CALIPER) study, https://caliper.research.sickkids.ca/#/

2. UCSF Clinical Labs at Parnassus, Mission Bay, and Mount Zion verified the adult reference range stated in the Abbott Creatinine, Enzymatic package insert (June 2016) by running 20 male and 20 female lab volunteers.

On September 10, 2020, the upper limit of the Abbott creatinine reference range in males was modified from 1.18 to 1.24 mg/dL to align with the reference range previously established in the UCSF Clinical Laboratories with the Beckman creatinine method.




Berkeley Outpatient Center and Peninsula Outpatient Center
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
≥ 19 years0.69-1.370.47-1.10

eGFRcr:
AgeeGFRcr
≥ 18 years> 59 mL/min/1.73 m2

Adult reference intervals adopted from the NHANES 2011-2012 survey that determined reference intervals in a multi-ethnic sample of males and females in the USA using an IDMS traceable creatinine assay.   The reference intervals were verified by testing 20 male and 20 female normal volunteers from UCSF Clinical Laboratories.  Lim E, et al, Racial/Ethnic-Specific Reference Intervals for Common Laboratory Tests: A Comparison among Asians, Blacks, Hispanics, and White.  Hawaii J Med Public Health, 2015;74:302-310

Additional Information

For Parnassus, Mission Bay and Mount Zion only:
In patients receiving catecholamine infusions (e.g., dopamine, dobutamine, norepinephrine, or epinephrine), falsely low serum/plasma creatinine results can occur with this enzymatic creatinine assay when blood is sampled through an indwelling catheter.  In these cases, accurate measurements of creatinine can be obtained by testing blood samples obtained by venipuncture instead of through an indwelling catheter (based on in-house studies and Saenger AK, Clinical Chemistry 2009, vol 55:9 1732–1736).

To convert mg/dL to µmol/L (SI units) multiply by 88.4.

For all creatinine assays:
Estimated GFR (eGFRcr) is reported with serum creatinine results in adults and is determined using the CKD-EPI (2021) equation without race coefficient (NKF-ASN recommendations). Creatinine results traceable to isotope dilution mass spec IDMS calibration. Note that the estimated GFR result is not reliable in certain groups including severely ill patients. Estimates of eGFR with the CKD-EPI (2021) equation like other equations may also be less accurate in specific ethnic groups (eg, Asians in the United States), pregnant women, and those with unusual muscle mass, body habitus, and weight (eg, morbid obesity, amputees). Reference: Assessment of Kidney Function. WWW.UpToDate.com

CKD-EPI (2021) equation without race coefficient:

eGFRcr = 142 x [min (sCR/kappa,1)alpha  x max(sCR/kappa, 1)-1.200] x 0.9938AGE x 1.012 [if female] 

Where:
-    sCR is serum creatinine in mg/dL
-    kappa is 0.7 for females and 0.9 for males
-    alpha is -0.241 for females and -0.302 for males
-    min indicates the minimum of sCR/kappa or 1, and max indicates the maximum of sCR/kappa or 1
- units are in mL/min/1.73 m2  body surface area


An eGFRcr will be calculated and reported with each plasma/serum creatinine result.

According to the National Kidney Disease Education Program, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Isotope Dilution Mass Spectrometry (IDMS)-traceable Schwartz equation http://www.nkdep.nih.gov/lab-evaluation/gfr-calculators/children-conventional-unit.shtml

Bedside IDMS-traceable Schwartz Equation for Children

GFR (mL/min/1.73 m2) = (0.41 x Height in cm) / Creatinine in mg/dL)
Administrative

CPT Codes

82565

LOINC Codes

2160-0
Complete View

Available Stat

Yes

Test Code

CRG

Test Group

Creatinine

Performing Lab

Parnassus, Mission Bay & Mt. Zion Chemistry
Berkeley Outpatient Center
Peninsula Outpatient Center
Saint Francis Chemistry
Saint Marys Chemistry

Performed

Parnassus, Mission Bay & Mt. Zion Chemistry: Test available 24 hours per day 7 days per week
Berkeley Outpatient Center (Mon-Fri 0800-1630)
Peninsula Outpatient Center (Mon-Fri 0800-1630)
Saint Francis Chemistry: Test available 24 hours per day 7 days per week
Saint Marys Chemistry: Test available 24 hours per day 7 days per week

Methodology

Parnassus, Mission Bay, Mt. Zion:  Enzymatic assay on Abbott Architect

Saint Francis and St Mary’s: Jaffe kinetic alkaline picrate on Abbott Architect

Berkeley Outpatient Center and Peninsula Outpatient Center: Enzymatic assay on Roche cobas c311

Collect

Preferred:  Light Green Top
Acceptable:  Gold Top or Red Top

Amount to Collect

1 mL blood

Sample Type

Plasma or serum

Preferred Volume

0.5 mL plasma or serum

Minimum Volume

0.2 mL plasma or serum

Units

Creatinine: mg/dL
eGFRcr:  mL/min/1.73 m2  body surface area

Reference Interval

Parnassus, Mission Bay, Mt. Zion, Saint Francis, & Saint Marys Chemistry
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
0 to 14 days0.32-0.920.32-0.92
15 days to < 2 years0.10-0.320.10-0.32
2 to < 5 years0.20-0.430.20-0.43
5 to < 12 years0.31-0.610.31-0.61
12 to < 15 years0.45-0.810.45-0.81
15 to < 19 years0.62-1.080.49-0.84
>= 19 years0.73-1.240.55-1.02

eGFRcr:
≥ 18 years> 59 mL/min/1.73 m2
< 18 yearsNot calculated (See Addtl. Info.)
1. Pediatric ranges adopted from Canadian Laboratory Initiative on Reference Interval Database (CALIPER) study, https://caliper.research.sickkids.ca/#/

2. UCSF Clinical Labs at Parnassus, Mission Bay, and Mount Zion verified the adult reference range stated in the Abbott Creatinine, Enzymatic package insert (June 2016) by running 20 male and 20 female lab volunteers.

On September 10, 2020, the upper limit of the Abbott creatinine reference range in males was modified from 1.18 to 1.24 mg/dL to align with the reference range previously established in the UCSF Clinical Laboratories with the Beckman creatinine method.




Berkeley Outpatient Center and Peninsula Outpatient Center
Creatinine:
AgeMale (mg/dL)Female (mg/dL)
≥ 19 years0.69-1.370.47-1.10

eGFRcr:
AgeeGFRcr
≥ 18 years> 59 mL/min/1.73 m2

Adult reference intervals adopted from the NHANES 2011-2012 survey that determined reference intervals in a multi-ethnic sample of males and females in the USA using an IDMS traceable creatinine assay.   The reference intervals were verified by testing 20 male and 20 female normal volunteers from UCSF Clinical Laboratories.  Lim E, et al, Racial/Ethnic-Specific Reference Intervals for Common Laboratory Tests: A Comparison among Asians, Blacks, Hispanics, and White.  Hawaii J Med Public Health, 2015;74:302-310

Synonyms

  • GFR
  • eGFRcr
  • glomerular filtration rate
  • CRG

Stability (from collection to initiation)

Room temperature:  7 days
Refrigerated:  7 days
Frozen at -20C:  3 months
 

Reported

STAT 1 hour, Routine 4 hours

Additional Information

For Parnassus, Mission Bay and Mount Zion only:
In patients receiving catecholamine infusions (e.g., dopamine, dobutamine, norepinephrine, or epinephrine), falsely low serum/plasma creatinine results can occur with this enzymatic creatinine assay when blood is sampled through an indwelling catheter.  In these cases, accurate measurements of creatinine can be obtained by testing blood samples obtained by venipuncture instead of through an indwelling catheter (based on in-house studies and Saenger AK, Clinical Chemistry 2009, vol 55:9 1732–1736).

To convert mg/dL to µmol/L (SI units) multiply by 88.4.

For all creatinine assays:
Estimated GFR (eGFRcr) is reported with serum creatinine results in adults and is determined using the CKD-EPI (2021) equation without race coefficient (NKF-ASN recommendations). Creatinine results traceable to isotope dilution mass spec IDMS calibration. Note that the estimated GFR result is not reliable in certain groups including severely ill patients. Estimates of eGFR with the CKD-EPI (2021) equation like other equations may also be less accurate in specific ethnic groups (eg, Asians in the United States), pregnant women, and those with unusual muscle mass, body habitus, and weight (eg, morbid obesity, amputees). Reference: Assessment of Kidney Function. WWW.UpToDate.com

CKD-EPI (2021) equation without race coefficient:

eGFRcr = 142 x [min (sCR/kappa,1)alpha  x max(sCR/kappa, 1)-1.200] x 0.9938AGE x 1.012 [if female] 

Where:
-    sCR is serum creatinine in mg/dL
-    kappa is 0.7 for females and 0.9 for males
-    alpha is -0.241 for females and -0.302 for males
-    min indicates the minimum of sCR/kappa or 1, and max indicates the maximum of sCR/kappa or 1
- units are in mL/min/1.73 m2  body surface area


An eGFRcr will be calculated and reported with each plasma/serum creatinine result.

According to the National Kidney Disease Education Program, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Isotope Dilution Mass Spectrometry (IDMS)-traceable Schwartz equation http://www.nkdep.nih.gov/lab-evaluation/gfr-calculators/children-conventional-unit.shtml

Bedside IDMS-traceable Schwartz Equation for Children

GFR (mL/min/1.73 m2) = (0.41 x Height in cm) / Creatinine in mg/dL)

CPT Codes

82565

LOINC Codes

2160-0

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