Human monocytic ehrlichiosis (HME), a tick-transmitted disease caused by Ehrlichia chaffeensis bacteria and is often described as 'spotless' rocky mountain spotted fever has been reported in various regions of the United States. Infected individuals produce specific antibody to E. chaffeensis which can be detected by the IFA test. A single IgG titer of 1:64 or greater indicates exposure to E. chaffeensis. A four fold or greater rise in IgG titer between acute and convalescent sera and/or an IgM titer of 1:20 or more is suggestive of recent or current infection.
This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
Synonyms
Human Monocytic ehrlichiosis
HME
Sample Type
Serum
Collect
Red top (Gold top NOT acceptable)
Amount to Collect
2 mL blood
Preferred Volume
1 mL serum
Minimum Volume
0.2 mL serum
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 1 week, frozen at -20C 1 month.
Unacceptable Conditions
Sample collected in Gold top
Test Code
EHRL
Test Group
Ehrlichia
Sendout
Yes
Performing Lab
Focus via Quest
Specimen Preparation
Refrigerate sample. Order Quest # 8524N
Preferred Volume
1 mL serum
Minimum Volume
0.2 mL serum
Unacceptable Conditions
Sample collected in Gold top
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 1 week, frozen at -20C 1 month.
Units
titer
Reference Interval
IgG: < 1:64 titer
IgM: < 1:20 titer
Additional Information
Human monocytic ehrlichiosis (HME), a tick-transmitted disease caused by Ehrlichia chaffeensis bacteria and is often described as 'spotless' rocky mountain spotted fever has been reported in various regions of the United States. Infected individuals produce specific antibody to E. chaffeensis which can be detected by the IFA test. A single IgG titer of 1:64 or greater indicates exposure to E. chaffeensis. A four fold or greater rise in IgG titer between acute and convalescent sera and/or an IgM titer of 1:20 or more is suggestive of recent or current infection.
This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
CPT Codes
86666-90 x2
LOINC Codes
45059-3
Available Stat
No
Test Code
EHRL
Test Group
Ehrlichia
Performing Lab
Focus via Quest
Sendout
Yes
Methodology
Immunofluorescence assay
Collect
Red top (Gold top NOT acceptable)
Amount to Collect
2 mL blood
Sample Type
Serum
Preferred Volume
1 mL serum
Minimum Volume
0.2 mL serum
Unacceptable Conditions
Sample collected in Gold top
Specimen Preparation
Refrigerate sample. Order Quest # 8524N
Units
titer
Reference Interval
IgG: < 1:64 titer
IgM: < 1:20 titer
Synonyms
Human Monocytic ehrlichiosis
HME
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 1 week, frozen at -20C 1 month.
Reported
Set up 6x per week, turnaround 4-5 days
Additional Information
Human monocytic ehrlichiosis (HME), a tick-transmitted disease caused by Ehrlichia chaffeensis bacteria and is often described as 'spotless' rocky mountain spotted fever has been reported in various regions of the United States. Infected individuals produce specific antibody to E. chaffeensis which can be detected by the IFA test. A single IgG titer of 1:64 or greater indicates exposure to E. chaffeensis. A four fold or greater rise in IgG titer between acute and convalescent sera and/or an IgM titer of 1:20 or more is suggestive of recent or current infection.
This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
CPT Codes
86666-90 x2
LOINC Codes
45059-3
Ordering
Available Stat
No
Performing Lab
Focus via Quest
Methodology
Immunofluorescence assay
Reported
Set up 6x per week, turnaround 4-5 days
Additional Information
Human monocytic ehrlichiosis (HME), a tick-transmitted disease caused by Ehrlichia chaffeensis bacteria and is often described as 'spotless' rocky mountain spotted fever has been reported in various regions of the United States. Infected individuals produce specific antibody to E. chaffeensis which can be detected by the IFA test. A single IgG titer of 1:64 or greater indicates exposure to E. chaffeensis. A four fold or greater rise in IgG titer between acute and convalescent sera and/or an IgM titer of 1:20 or more is suggestive of recent or current infection.
This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
Synonyms
Human Monocytic ehrlichiosis
HME
Collection
Sample Type
Serum
Collect
Red top (Gold top NOT acceptable)
Amount to Collect
2 mL blood
Preferred Volume
1 mL serum
Minimum Volume
0.2 mL serum
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 1 week, frozen at -20C 1 month.
Unacceptable Conditions
Sample collected in Gold top
Processing
Test Code
EHRL
Test Group
Ehrlichia
Sendout
Yes
Performing Lab
Focus via Quest
Specimen Preparation
Refrigerate sample. Order Quest # 8524N
Preferred Volume
1 mL serum
Minimum Volume
0.2 mL serum
Unacceptable Conditions
Sample collected in Gold top
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 1 week, frozen at -20C 1 month.
Result Interpretation
Units
titer
Reference Interval
IgG: < 1:64 titer
IgM: < 1:20 titer
Additional Information
Human monocytic ehrlichiosis (HME), a tick-transmitted disease caused by Ehrlichia chaffeensis bacteria and is often described as 'spotless' rocky mountain spotted fever has been reported in various regions of the United States. Infected individuals produce specific antibody to E. chaffeensis which can be detected by the IFA test. A single IgG titer of 1:64 or greater indicates exposure to E. chaffeensis. A four fold or greater rise in IgG titer between acute and convalescent sera and/or an IgM titer of 1:20 or more is suggestive of recent or current infection.
This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
Administrative
CPT Codes
86666-90 x2
LOINC Codes
45059-3
Complete View
Available Stat
No
Test Code
EHRL
Test Group
Ehrlichia
Performing Lab
Focus via Quest
Sendout
Yes
Methodology
Immunofluorescence assay
Collect
Red top (Gold top NOT acceptable)
Amount to Collect
2 mL blood
Sample Type
Serum
Preferred Volume
1 mL serum
Minimum Volume
0.2 mL serum
Unacceptable Conditions
Sample collected in Gold top
Specimen Preparation
Refrigerate sample. Order Quest # 8524N
Units
titer
Reference Interval
IgG: < 1:64 titer
IgM: < 1:20 titer
Synonyms
Human Monocytic ehrlichiosis
HME
Stability (from collection to initiation)
Room temperature 4 days, refrigerated 1 week, frozen at -20C 1 month.
Reported
Set up 6x per week, turnaround 4-5 days
Additional Information
Human monocytic ehrlichiosis (HME), a tick-transmitted disease caused by Ehrlichia chaffeensis bacteria and is often described as 'spotless' rocky mountain spotted fever has been reported in various regions of the United States. Infected individuals produce specific antibody to E. chaffeensis which can be detected by the IFA test. A single IgG titer of 1:64 or greater indicates exposure to E. chaffeensis. A four fold or greater rise in IgG titer between acute and convalescent sera and/or an IgM titer of 1:20 or more is suggestive of recent or current infection.
This test was developed and its performance characteristics determined by Quest Diagnostics Nichols Institute. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.
