Available Stat

No

Performing Lab

Medical Genomics - Cytogenetics

Methodology

Fluorescent in-situ hybridization

Reported

7-14 days

Synonyms

  • +8
  • Cytogenetic analysis
  • Karyotype
  • Karyotyping
  • TRIS8
  • BTRI8

Sample Type

Heparinized whole blood, bone marrow, bone core

Collect

Blood & bone marrow aspirate: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics. Dark Green top also acceptable

Bone marrow core: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics.

Amount to Collect

See preferred volume.

Preferred Volume

Whole blood: 2 mL
Bone marrow aspirate: 2 mL
?Bone marrow biopsy: 2 cm

Minimum Volume

Whole blood: 1 mL
Bone marrow aspirate: 1 mL
?Bone marrow biopsy: 1 cm

Remarks

Bone marrow is the preferred specimen, but heparinized peripheral blood may be submitted if a large number of malignant cells are present.

Collect bone marrow in a syringe, transfer to Dark Green top vacutainer and gently invert the tube several times for good mixing.

If a dry tap is obtained, consult the Laboratory Medicine resident in Hematology regarding the possible submission of a green top tube of
peripheral blood.

Contact Hematology if the specimen is more than 24 hours old.

Stability (from collection to initiation)

48 hours

Unacceptable Conditions

Insufficient volume; unlabeled tubes; clotted samples; broken, leaking or contaminated tubes; frozen samples.

Test Code

BTRI8: Blood
TRIS8: Bone marrow

Performing Lab

Medical Genomics - Cytogenetics

Specimen Preparation

Maintain sample at room temperature. Transport to CB Cytogenetics within 24 hours

Preferred Volume

Whole blood: 2 mL
Bone marrow aspirate: 2 mL
?Bone marrow biopsy: 2 cm

Minimum Volume

Whole blood: 1 mL
Bone marrow aspirate: 1 mL
?Bone marrow biopsy: 1 cm

Unacceptable Conditions

Insufficient volume; unlabeled tubes; clotted samples; broken, leaking or contaminated tubes; frozen samples.

Stability (from collection to initiation)

48 hours

Reference Interval

Not detected

CPT Codes

88275, 88271

LDT or Modified FDA

Yes

LOINC Codes

21773-7

Available Stat

No

Test Code

BTRI8: Blood
TRIS8: Bone marrow

Performing Lab

Medical Genomics - Cytogenetics

Methodology

Fluorescent in-situ hybridization

Remarks

Bone marrow is the preferred specimen, but heparinized peripheral blood may be submitted if a large number of malignant cells are present.

Collect bone marrow in a syringe, transfer to Dark Green top vacutainer and gently invert the tube several times for good mixing.

If a dry tap is obtained, consult the Laboratory Medicine resident in Hematology regarding the possible submission of a green top tube of
peripheral blood.

Contact Hematology if the specimen is more than 24 hours old.

Collect

Blood & bone marrow aspirate: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics. Dark Green top also acceptable

Bone marrow core: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics.

Amount to Collect

See preferred volume.

Sample Type

Heparinized whole blood, bone marrow, bone core

Preferred Volume

Whole blood: 2 mL
Bone marrow aspirate: 2 mL
?Bone marrow biopsy: 2 cm

Minimum Volume

Whole blood: 1 mL
Bone marrow aspirate: 1 mL
?Bone marrow biopsy: 1 cm

Unacceptable Conditions

Insufficient volume; unlabeled tubes; clotted samples; broken, leaking or contaminated tubes; frozen samples.

Specimen Preparation

Maintain sample at room temperature. Transport to CB Cytogenetics within 24 hours

Reference Interval

Not detected

Synonyms

  • +8
  • Cytogenetic analysis
  • Karyotype
  • Karyotyping
  • TRIS8
  • BTRI8

Stability (from collection to initiation)

48 hours

Reported

7-14 days

CPT Codes

88275, 88271

LDT or Modified FDA

Yes

LOINC Codes

21773-7
Ordering

Available Stat

No

Performing Lab

Medical Genomics - Cytogenetics

Methodology

Fluorescent in-situ hybridization

Reported

7-14 days

Synonyms

  • +8
  • Cytogenetic analysis
  • Karyotype
  • Karyotyping
  • TRIS8
  • BTRI8
Collection

Sample Type

Heparinized whole blood, bone marrow, bone core

Collect

Blood & bone marrow aspirate: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics. Dark Green top also acceptable

Bone marrow core: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics.

Amount to Collect

See preferred volume.

Preferred Volume

Whole blood: 2 mL
Bone marrow aspirate: 2 mL
?Bone marrow biopsy: 2 cm

Minimum Volume

Whole blood: 1 mL
Bone marrow aspirate: 1 mL
?Bone marrow biopsy: 1 cm

Remarks

Bone marrow is the preferred specimen, but heparinized peripheral blood may be submitted if a large number of malignant cells are present.

Collect bone marrow in a syringe, transfer to Dark Green top vacutainer and gently invert the tube several times for good mixing.

If a dry tap is obtained, consult the Laboratory Medicine resident in Hematology regarding the possible submission of a green top tube of
peripheral blood.

Contact Hematology if the specimen is more than 24 hours old.

Stability (from collection to initiation)

48 hours

Unacceptable Conditions

Insufficient volume; unlabeled tubes; clotted samples; broken, leaking or contaminated tubes; frozen samples.
Processing

Test Code

BTRI8: Blood
TRIS8: Bone marrow

Performing Lab

Medical Genomics - Cytogenetics

Specimen Preparation

Maintain sample at room temperature. Transport to CB Cytogenetics within 24 hours

Preferred Volume

Whole blood: 2 mL
Bone marrow aspirate: 2 mL
?Bone marrow biopsy: 2 cm

Minimum Volume

Whole blood: 1 mL
Bone marrow aspirate: 1 mL
?Bone marrow biopsy: 1 cm

Unacceptable Conditions

Insufficient volume; unlabeled tubes; clotted samples; broken, leaking or contaminated tubes; frozen samples.

Stability (from collection to initiation)

48 hours
Result Interpretation

Reference Interval

Not detected
Administrative

CPT Codes

88275, 88271

LDT or Modified FDA

Yes

LOINC Codes

21773-7
Complete View

Available Stat

No

Test Code

BTRI8: Blood
TRIS8: Bone marrow

Performing Lab

Medical Genomics - Cytogenetics

Methodology

Fluorescent in-situ hybridization

Remarks

Bone marrow is the preferred specimen, but heparinized peripheral blood may be submitted if a large number of malignant cells are present.

Collect bone marrow in a syringe, transfer to Dark Green top vacutainer and gently invert the tube several times for good mixing.

If a dry tap is obtained, consult the Laboratory Medicine resident in Hematology regarding the possible submission of a green top tube of
peripheral blood.

Contact Hematology if the specimen is more than 24 hours old.

Collect

Blood & bone marrow aspirate: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics. Dark Green top also acceptable

Bone marrow core: 15 mL centrifuge tube with transport media (RPMI, FBS, L-Glutamine, Sodium Heparin and PenStrep). Available from Cytogenetics.

Amount to Collect

See preferred volume.

Sample Type

Heparinized whole blood, bone marrow, bone core

Preferred Volume

Whole blood: 2 mL
Bone marrow aspirate: 2 mL
?Bone marrow biopsy: 2 cm

Minimum Volume

Whole blood: 1 mL
Bone marrow aspirate: 1 mL
?Bone marrow biopsy: 1 cm

Unacceptable Conditions

Insufficient volume; unlabeled tubes; clotted samples; broken, leaking or contaminated tubes; frozen samples.

Specimen Preparation

Maintain sample at room temperature. Transport to CB Cytogenetics within 24 hours

Reference Interval

Not detected

Synonyms

  • +8
  • Cytogenetic analysis
  • Karyotype
  • Karyotyping
  • TRIS8
  • BTRI8

Stability (from collection to initiation)

48 hours

Reported

7-14 days

CPT Codes

88275, 88271

LDT or Modified FDA

Yes

LOINC Codes

21773-7