LAB31

PHENY TOT

NOTE - Pheny total testing performed at UCH.  Testing for Pheny F Panel (free and total phenytoin) will be sent to ARUP utilizing LAB176)

UCH Clinical Laboratory - Core

One 6.0 mL red top no gel, serum (clot activator).

At least 0.5 mL whole blood in a red top no gel, serum (clot activator).

Specimen not properly identified; incorrect container; insufficient sample volume.

Internal: Deliver to lab immediately at ambient temperature..
Offsite: Allow to clot 30 minutes, immediately centrifuge , place serum in aliquot container and send at 2-8 degrees C.

Daily

Before centrifugation: Ambient, 1 hour.
After centrifugation: Refrigerated, 1 month.
Serum aliquot: Refrigerated, 1 month; Frozen (-20 degrees C), 3 months..

Include dosage information. Draw trough level immediately before the next dose. If toxicity is suspected draw at any time.

Daily

Immuno-Turbidimetry

Same day

LAB31

PHENY TOT

NOTE - Pheny total testing performed at UCH.  Testing for Pheny F Panel (free and total phenytoin) will be sent to ARUP utilizing LAB176)

10.0-20.0 ug/mL

Effective 05/20/2014:

The expected range is provided only as a guide, and individual patient results should be interpreted in light of other clinical signs and symptoms.  For effective treatment, some patients may require serum levels outside this range.  Peak concentrations above 20 μg/mL are often associated with toxicity.

Before 05/20/2014:

Toxic levels of total Phenytoin are greater than 20.0 ug/mL.

Falsely elevated Phenytoin concentrations have been observed in patients with renal deficiency or failure.

80185