Ordering Recommendations

Use for the qualitative detection of IgG antibodies against SARS-CoV2 (COVID-19) to evaluate exposure, post vaccination, or post monoclonal antibody treatment.

Specimen Type

Serum or Plasma

Collection Method

Standard venipuncture

Collect

1 Gold tube (Serum Separator)

Alternate Specimen Container

or 1 Lavender tube (EDTA)


or 1 Green tube (Lithium heparin)

Minimum Volume

0.5 mL

Optimum Volume

1 mL

Patient Preparation

None

Specimen Preparation

Centrifuge for complete separation of serum or plasma.  Plasma must be removed from cells within 2 hours.  Aliquot plasma into a transfer tube.

Stability (from collection to initiation)

  • 15-30°C up to 8 hours
  • 2-8°C up to 2 days
  • -20°C up to 30 days

Storage/Transport Temperature

Refrigerate

Unacceptable Conditions

Samples that are severely hemolyzed or insufficient quantity will be rejected

CPT Codes

86769

LOINC

  • 94507-1

Test Availability

Batched

Performed

M, Tu, W, Th, F, Sa, Su

Methodology

EIA

Reported

Within 24-48 hours of receipt

Department

NCHB2 

Performing Lab

Alverno 

Reference Interval

Negative

Interpretive Data

Negative or Positive
This antibody can be useful in detecting immunity developed due to SARS-CoV2 infection OR after vaccination OR monoclonal antibody treatment.  IgG antibodies can be detected in most patients 2 weeks post symptom onset or post vaccination.

This test has been authorized by the FDA under an Emergency Use Authorization (EUA).  Negative results do not rule out SARS-CoV2 infection, particularly in those who have been in contact with the virus.  Follow-up testing with a molecular diagnositic test should be considered to rule out infection in these individuals.  Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV2 infection or to inform infection status.  

Positive results may be due to past or present infection with non-SARS CoV2 coronavirus strains such as cornovirus HKU1, NL63, OC43, or 229E.

This test should not be used to screen donated blood.
 

Synonyms

  • 2019-nCoV
  • Coronavirus Disease - 2019
  • COVID-19 Illness
  • COVID-2019
  • COVID19 IgG Ab
  • SARS-CoV-2
  • Wuhan
  • 3002776
Test Information

Ordering Recommendations

Use for the qualitative detection of IgG antibodies against SARS-CoV2 (COVID-19) to evaluate exposure, post vaccination, or post monoclonal antibody treatment.

Specimen Type

Serum or Plasma

Collection Method

Standard venipuncture

Collect

1 Gold tube (Serum Separator)

Alternate Specimen Container

or 1 Lavender tube (EDTA)


or 1 Green tube (Lithium heparin)

Minimum Volume

0.5 mL

Optimum Volume

1 mL

Patient Preparation

None

Specimen Preparation

Centrifuge for complete separation of serum or plasma.  Plasma must be removed from cells within 2 hours.  Aliquot plasma into a transfer tube.

Stability (from collection to initiation)

  • 15-30°C up to 8 hours
  • 2-8°C up to 2 days
  • -20°C up to 30 days

Storage/Transport Temperature

Refrigerate

Unacceptable Conditions

Samples that are severely hemolyzed or insufficient quantity will be rejected

CPT Codes

86769

LOINC

  • 94507-1

Test Availability

Batched

Performed

M, Tu, W, Th, F, Sa, Su

Methodology

EIA

Reported

Within 24-48 hours of receipt

Department

NCHB2 

Performing Lab

Alverno 

Reference Interval

Negative

Interpretive Data

Negative or Positive
This antibody can be useful in detecting immunity developed due to SARS-CoV2 infection OR after vaccination OR monoclonal antibody treatment.  IgG antibodies can be detected in most patients 2 weeks post symptom onset or post vaccination.

This test has been authorized by the FDA under an Emergency Use Authorization (EUA).  Negative results do not rule out SARS-CoV2 infection, particularly in those who have been in contact with the virus.  Follow-up testing with a molecular diagnositic test should be considered to rule out infection in these individuals.  Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV2 infection or to inform infection status.  

Positive results may be due to past or present infection with non-SARS CoV2 coronavirus strains such as cornovirus HKU1, NL63, OC43, or 229E.

This test should not be used to screen donated blood.
 

Synonyms

  • 2019-nCoV
  • Coronavirus Disease - 2019
  • COVID-19 Illness
  • COVID-2019
  • COVID19 IgG Ab
  • SARS-CoV-2
  • Wuhan
  • 3002776