Use to monitor coccidioidal antibody titer in serum in response to treatment. For initial diagnosis of coccidioidomycosis, refer to Coccidioides Antibodies Reflexive Panel, Serum (3001982).
Orderable SIM Number(s)
FUNGAL SEROLOGY, COCCI, COMP FIX (LAB123232)
Synonyms
San Joaquin Fever Antibody by CF
Valley Fever by CF
Coccidioides Serology, Complement Fixation
Cocci IgG, IgM CF
Coccidioidomycosis IgG/IgM
San Joaquin Fever Antibody
Valley Fever antibodies
Coccidioides immitis
Coccidioidomycosis
Valley Fever
LAB123232
ARUP Test Code
0050170
Collect
Serum separator tube (SST).
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.6 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens..
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.
Mark specimens plainly as "acute" or "convalescent."
Reference Interval
Less than 1:2
Interpretive Data
A titer of 1:2 or greater suggests past or current infection. However, greater than 30 percent of cases with chronic residual pulmonary disease have negative complement fixation (CF) tests. Titers of less than 1:32 (even as low as 1:2) may indicate past infection or self-limited disease; anticoccidioidal CF antibody titers in excess of 1:16 may indicate disseminated infection. CF serology may be used to follow therapy. Antibody in CSF is considered diagnostic for coccidioidal meningitis, although 10 percent of patients with coccidioidal meningitis will not have antibody in CSF.
CPT Codes
86635
Billable SIM Number(s)
3058663501
LOINC
33380-7
Overview
Ordering Recommendations
Use to monitor coccidioidal antibody titer in serum in response to treatment. For initial diagnosis of coccidioidomycosis, refer to Coccidioides Antibodies Reflexive Panel, Serum (3001982).
Orderable SIM Number(s)
FUNGAL SEROLOGY, COCCI, COMP FIX (LAB123232)
Synonyms
San Joaquin Fever Antibody by CF
Valley Fever by CF
Coccidioides Serology, Complement Fixation
Cocci IgG, IgM CF
Coccidioidomycosis IgG/IgM
San Joaquin Fever Antibody
Valley Fever antibodies
Coccidioides immitis
Coccidioidomycosis
Valley Fever
LAB123232
ARUP Test Code
0050170
Specimen
Collect
Serum separator tube (SST).
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.6 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens..
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.
Mark specimens plainly as "acute" or "convalescent."
Interpretive
Reference Interval
Less than 1:2
Interpretive Data
A titer of 1:2 or greater suggests past or current infection. However, greater than 30 percent of cases with chronic residual pulmonary disease have negative complement fixation (CF) tests. Titers of less than 1:32 (even as low as 1:2) may indicate past infection or self-limited disease; anticoccidioidal CF antibody titers in excess of 1:16 may indicate disseminated infection. CF serology may be used to follow therapy. Antibody in CSF is considered diagnostic for coccidioidal meningitis, although 10 percent of patients with coccidioidal meningitis will not have antibody in CSF.
