Use for kidney stone risk assessment and monitoring; includes interpretation of data. Panel includes calcium, chloride, citric acid, creatinine, magnesium, oxalate, pH, phosphorous, potassium, sodium, sulfate, and uric acid.
Orderable SIM Number(s)
SUPERSATURATION PROFILE URINE (LAB123510)
Synonyms
phosphorus
potassium
Stone Risk Profile
sulfate
uric acid
creatinine
magnesium
choride
Calculi Risk
Calculus Risk
citric aci
Kidney Stone Profile
Kidney Stone Risk Assessment
oxalate
LAB123510
ARUP Test Code
2008771
Collect
24-hour urine. Refrigerate during collection.
Specimen Preparation
Thoroughly mix entire collection (24-hour) in one container. Transport four separate 4 mL aliquots of urine using Calculi Risk/Supersaturation Urine Collection Kit (ARUP supply# 46007). Available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. Do not exceed 4 mL in tubes. Aliquot according to the following specifications: 1st aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately. 2nd aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately. 3rd aliquot (pH 9): Transfer 4 mL urine into a Sodium Carbonate Tube. (Min: 4 mL) Mix well. Freeze immediately. 4th aliquot: Transfer 4 mL urine into an Unpreserved Tube. (Min: 4 mL) Freeze immediately. If collection kit is unavailable, transport four 4 mL unadjusted aliquots of urine. New York State Clients: Two 100 mL aliquots
Storage/Transport Temperature
Send entire 24 hour Urine collection to ARL, refrigerated.
If aliquoted into the Calculi Risk/Supersaturation Urine Collection Kit (Available from ARL), send frozen.
Call ARL for the Calculi Risk/Supersaturation Urine Collection Kit.
Remarks
Record total volume and collection time interval on tube and test request form.
Reference Interval
Components
Reference Interval
Calcium, Urine - per 24h
Diet
Reference Interval (mg/d)
Calcium-free diet
5-40
Low calcium diet (less than 800 mg/d)
50-150
Average calcium diet (about 800 mg/d)
100-250
High calcium diet (greater than 800 mg/d)
> 250
Creatinine, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
3-8 years
140-700
140-700
9-12 years
300-1300
300-1300
13-17 years
500-2300
400-1600
18-50 years
1000-2500
700-1600
51-80 years
800-2100
500-1400
81 years and older
600-2000
400-1300
Magnesium, Urine per 24h
12-199 mg/d
Phosphorus, Urine - per 24h
400-1300 mg/d
Uric Acid, Urine - per 24h
250-750 mg/d
Citric Acid, Urine - per 24h
18 years and older: 320-1240 mg/d
Oxalate, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
0-12 years
7-31
7-31
13 years and older
16-49
13-40
Sodium, Urine - per 24h
51-286 mmol/d
Potassium, Urine - per 24h
25-125 mmol/d
Chloride, Urine - per 24h
140-250 mmol/d
Sulfate, Urine - per 24h
6-30 mmol/d
Interpretive Data
The values determined for this specimen are placed on the chart to indicate the approximate risk associated with the particular concentrations. Increased risk is to the right of center; decreased risk, to the left. Relative supersaturation calculated for calcium oxalate, calcium hydrogen phosphate (brushite) and uric acid calculi is displayed. Relative risk increases from the middle to the right side of this chart.
Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Use for kidney stone risk assessment and monitoring; includes interpretation of data. Panel includes calcium, chloride, citric acid, creatinine, magnesium, oxalate, pH, phosphorous, potassium, sodium, sulfate, and uric acid.
Orderable SIM Number(s)
SUPERSATURATION PROFILE URINE (LAB123510)
Synonyms
phosphorus
potassium
Stone Risk Profile
sulfate
uric acid
creatinine
magnesium
choride
Calculi Risk
Calculus Risk
citric aci
Kidney Stone Profile
Kidney Stone Risk Assessment
oxalate
LAB123510
ARUP Test Code
2008771
Specimen
Collect
24-hour urine. Refrigerate during collection.
Specimen Preparation
Thoroughly mix entire collection (24-hour) in one container. Transport four separate 4 mL aliquots of urine using Calculi Risk/Supersaturation Urine Collection Kit (ARUP supply# 46007). Available online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. Do not exceed 4 mL in tubes. Aliquot according to the following specifications: 1st aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately. 2nd aliquot (pH 2): Transfer 4 mL urine into a Sulfamic Acid Tube. (Min: 4 mL) Mix well. Freeze immediately. 3rd aliquot (pH 9): Transfer 4 mL urine into a Sodium Carbonate Tube. (Min: 4 mL) Mix well. Freeze immediately. 4th aliquot: Transfer 4 mL urine into an Unpreserved Tube. (Min: 4 mL) Freeze immediately. If collection kit is unavailable, transport four 4 mL unadjusted aliquots of urine. New York State Clients: Two 100 mL aliquots
Storage/Transport Temperature
Send entire 24 hour Urine collection to ARL, refrigerated.
If aliquoted into the Calculi Risk/Supersaturation Urine Collection Kit (Available from ARL), send frozen.
Call ARL for the Calculi Risk/Supersaturation Urine Collection Kit.
Remarks
Record total volume and collection time interval on tube and test request form.
Interpretive
Reference Interval
Components
Reference Interval
Calcium, Urine - per 24h
Diet
Reference Interval (mg/d)
Calcium-free diet
5-40
Low calcium diet (less than 800 mg/d)
50-150
Average calcium diet (about 800 mg/d)
100-250
High calcium diet (greater than 800 mg/d)
> 250
Creatinine, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
3-8 years
140-700
140-700
9-12 years
300-1300
300-1300
13-17 years
500-2300
400-1600
18-50 years
1000-2500
700-1600
51-80 years
800-2100
500-1400
81 years and older
600-2000
400-1300
Magnesium, Urine per 24h
12-199 mg/d
Phosphorus, Urine - per 24h
400-1300 mg/d
Uric Acid, Urine - per 24h
250-750 mg/d
Citric Acid, Urine - per 24h
18 years and older: 320-1240 mg/d
Oxalate, Urine - per 24h
Age
Male (mg/d)
Female (mg/d)
0-12 years
7-31
7-31
13 years and older
16-49
13-40
Sodium, Urine - per 24h
51-286 mmol/d
Potassium, Urine - per 24h
25-125 mmol/d
Chloride, Urine - per 24h
140-250 mmol/d
Sulfate, Urine - per 24h
6-30 mmol/d
Interpretive Data
The values determined for this specimen are placed on the chart to indicate the approximate risk associated with the particular concentrations. Increased risk is to the right of center; decreased risk, to the left. Relative supersaturation calculated for calcium oxalate, calcium hydrogen phosphate (brushite) and uric acid calculi is displayed. Relative risk increases from the middle to the right side of this chart.
Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
