Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day.
Ordering Recommendations
Primarily for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.
Patient Preparation and Collection Instructions
Minimum to collect: 1mL in serum separator tube
Collect
Serum separator tube, or plain red.
Storage/Transport Temperature
CRITICAL FROZEN. Additional specimens must be submitted when multiple tests are ordered.
Stability (from collection to initiation)
After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year
Unacceptable Conditions
Refrigerated specimens. Contaminated or heat inactivated specimens.
Performed
Sun-Sat
Reported
1-4 days
Methodology
Quantitative Multiplex Bead Assay
Reference Interval
Components
Reference Interval (pg/mL)
Interleukin 2 Receptor, Soluble, Serum
175.3-858.2
Interleukin 12, Serum
1.9 or less
Interferon gamma, Serum
4.2 or less
Interleukin 4, Serum
2.2 or less
Interleukin 5, Serum
2.1 or less
Interleukin 10, Serum
2.8 or less
Interleukin 13, Serum
2.3 or less
Interleukin 1 beta, Serum
6.7 or less
Interleukin 6, Serum
2.0 or less
Interleukin 8, Serum
3.0 or less
Tumor Necrosis Factor - alpha, Serum
7.2 or less
Interleukin 2, Serum
2.1 or less
Interleukin 17, Serum
1.4 or less
Interpretive Data
Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.
Specimen Preparation
Separate serum cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)
CPT Codes
83520 x12; 83529
LOINC
76039-7
41760-0
27415-9
27161-9
33938-2
26848-2
33822-8
13629-1
26881-3
33211-4
3074-2
33939-0
82334-4
Synonyms
cytokine
Cytokine 12
cytokines
IFN
IFN G
IFN Gamma
IL
IL 0
IL 1
IL 1 B
IL 10
IL 12
IL 13
IL 17
IL 1B
IL 2
IL 2 R
IL 2R
IL 4
IL 5
IL 6
IL 8
IL-1 Beta
IL-10
IL-12
IL-13
IL-2
IL-2R
IL-4
IL-5
IL-6
IL-8
IL1
IL1 B
IL1 Beta
IL10
IL12
IL13
IL17
IL2
IL2 R
IL2 Receptor
IL2R
IL4
IL5
IL6
IL8
TNF Alpha
Tumor Necrosis Factor alpha
Collection and Testing Information
Notes
Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day.
Ordering Recommendations
Primarily for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.
Patient Preparation and Collection Instructions
Minimum to collect: 1mL in serum separator tube
Collect
Serum separator tube, or plain red.
Storage/Transport Temperature
CRITICAL FROZEN. Additional specimens must be submitted when multiple tests are ordered.
Stability (from collection to initiation)
After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year
Unacceptable Conditions
Refrigerated specimens. Contaminated or heat inactivated specimens.
Performed
Sun-Sat
Reported
1-4 days
Methodology
Quantitative Multiplex Bead Assay
Reference Interval
Components
Reference Interval (pg/mL)
Interleukin 2 Receptor, Soluble, Serum
175.3-858.2
Interleukin 12, Serum
1.9 or less
Interferon gamma, Serum
4.2 or less
Interleukin 4, Serum
2.2 or less
Interleukin 5, Serum
2.1 or less
Interleukin 10, Serum
2.8 or less
Interleukin 13, Serum
2.3 or less
Interleukin 1 beta, Serum
6.7 or less
Interleukin 6, Serum
2.0 or less
Interleukin 8, Serum
3.0 or less
Tumor Necrosis Factor - alpha, Serum
7.2 or less
Interleukin 2, Serum
2.1 or less
Interleukin 17, Serum
1.4 or less
Interpretive Data
Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.
Lab Personnel Use
Specimen Preparation
Separate serum cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)
