Notes

Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day.

Ordering Recommendations

Primarily for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.

Patient Preparation and Collection Instructions

Minimum to collect: 1mL in serum separator tube

Collect

Serum separator tube, or plain red.

Storage/Transport Temperature

CRITICAL FROZEN. Additional specimens must be submitted when multiple tests are ordered.

Stability (from collection to initiation)

After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year

Unacceptable Conditions

Refrigerated specimens. Contaminated or heat inactivated specimens.

Performed

Sun-Sat

Reported

1-4 days

Methodology

Quantitative Multiplex Bead Assay

Reference Interval

Components
Reference Interval (pg/mL)
Interleukin 2 Receptor, Soluble, Serum175.3-858.2
Interleukin 12, Serum1.9 or less
Interferon gamma, Serum4.2 or less
Interleukin 4, Serum2.2 or less
Interleukin 5, Serum2.1 or less
Interleukin 10, Serum2.8 or less
Interleukin 13, Serum2.3 or less
Interleukin 1 beta, Serum6.7 or less
Interleukin 6, Serum2.0 or less
Interleukin 8, Serum3.0 or less
Tumor Necrosis Factor - alpha, Serum7.2 or less
Interleukin 2, Serum2.1 or less
Interleukin 17, Serum1.4 or less

Interpretive Data

Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.

Specimen Preparation

Separate serum cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

CPT Codes

83520 x12; 83529

LOINC

  • 76039-7
  • 41760-0
  • 27415-9
  • 27161-9
  • 33938-2
  • 26848-2
  • 33822-8
  • 13629-1
  • 26881-3
  • 33211-4
  • 3074-2
  • 33939-0
  • 82334-4

Synonyms

  • cytokine
  • Cytokine 12
  • cytokines
  • IFN
  • IFN G
  • IFN Gamma
  • IL
  • IL 0
  • IL 1
  • IL 1 B
  • IL 10
  • IL 12
  • IL 13
  • IL 17
  • IL 1B
  • IL 2
  • IL 2 R
  • IL 2R
  • IL 4
  • IL 5
  • IL 6
  • IL 8
  • IL-1 Beta
  • IL-10
  • IL-12
  • IL-13
  • IL-2
  • IL-2R
  • IL-4
  • IL-5
  • IL-6
  • IL-8
  • IL1
  • IL1 B
  • IL1 Beta
  • IL10
  • IL12
  • IL13
  • IL17
  • IL2
  • IL2 R
  • IL2 Receptor
  • IL2R
  • IL4
  • IL5
  • IL6
  • IL8
  • TNF Alpha
  • Tumor Necrosis Factor alpha
Collection and Testing Information

Notes

Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day.

Ordering Recommendations

Primarily for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.

Patient Preparation and Collection Instructions

Minimum to collect: 1mL in serum separator tube

Collect

Serum separator tube, or plain red.

Storage/Transport Temperature

CRITICAL FROZEN. Additional specimens must be submitted when multiple tests are ordered.

Stability (from collection to initiation)

After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year

Unacceptable Conditions

Refrigerated specimens. Contaminated or heat inactivated specimens.

Performed

Sun-Sat

Reported

1-4 days

Methodology

Quantitative Multiplex Bead Assay

Reference Interval

Components
Reference Interval (pg/mL)
Interleukin 2 Receptor, Soluble, Serum175.3-858.2
Interleukin 12, Serum1.9 or less
Interferon gamma, Serum4.2 or less
Interleukin 4, Serum2.2 or less
Interleukin 5, Serum2.1 or less
Interleukin 10, Serum2.8 or less
Interleukin 13, Serum2.3 or less
Interleukin 1 beta, Serum6.7 or less
Interleukin 6, Serum2.0 or less
Interleukin 8, Serum3.0 or less
Tumor Necrosis Factor - alpha, Serum7.2 or less
Interleukin 2, Serum2.1 or less
Interleukin 17, Serum1.4 or less

Interpretive Data

Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.

Lab Personnel Use

Specimen Preparation

Separate serum cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

CPT Codes

83520 x12; 83529

LOINC

  • 76039-7
  • 41760-0
  • 27415-9
  • 27161-9
  • 33938-2
  • 26848-2
  • 33822-8
  • 13629-1
  • 26881-3
  • 33211-4
  • 3074-2
  • 33939-0
  • 82334-4

Synonyms

  • cytokine
  • Cytokine 12
  • cytokines
  • IFN
  • IFN G
  • IFN Gamma
  • IL
  • IL 0
  • IL 1
  • IL 1 B
  • IL 10
  • IL 12
  • IL 13
  • IL 17
  • IL 1B
  • IL 2
  • IL 2 R
  • IL 2R
  • IL 4
  • IL 5
  • IL 6
  • IL 8
  • IL-1 Beta
  • IL-10
  • IL-12
  • IL-13
  • IL-2
  • IL-2R
  • IL-4
  • IL-5
  • IL-6
  • IL-8
  • IL1
  • IL1 B
  • IL1 Beta
  • IL10
  • IL12
  • IL13
  • IL17
  • IL2
  • IL2 R
  • IL2 Receptor
  • IL2R
  • IL4
  • IL5
  • IL6
  • IL8
  • TNF Alpha
  • Tumor Necrosis Factor alpha