This flow cytometry assay is intended to be used as a screening test. Screening tests are not 100% sensitive nor specific, and a normal result should not preclude molecular sequencing if a patient's clinical presentation suggests that the probability of a diagnosis is high.
Additional information regarding the accuracy of this flow cytometry screening assay is available.[1]
1. Gifford, CE; Weingartner, E; Villanueva, J; Johnson, J; Zhang, K; Filipovich AH; Bleesing, J; Marsh, RA. “Clinical flow cytometric screening of SAP and XIAP expression accurately identifies patients with SH2D1A and XIAP/BIRC4 mutations.” Cytometry B Clin Cytom. v. 86 p. 263-271.
CPT Codes
88184, 88185 x 6, 88187
Collection
Collect
Blood in 4mL DkGr NaHep. Collect only Mon-Fri. On Fridays, must be received to Burnet lab by 1100
Minimum Collection Volume
1mL
Shipping/Handling Instructions (Lab Use Only)
Do not spin. Critical: Room Temp
External Client Shipping and Handling
Sample must be received within 24 hours of collection.
Stability (from collection to initiation)
Room Temp 24 Hours
Notes
Please note that this combined assay replaces the individual SAP and XIAP assays.
This flow cytometry assay is intended to be used as a screening test. Screening tests are not 100% sensitive nor specific, and a normal result should not preclude molecular sequencing if a patient's clinical presentation suggests that the probability of a diagnosis is high.
Additional information regarding the accuracy of this flow cytometry screening assay is available.[1]
1. Gifford, CE; Weingartner, E; Villanueva, J; Johnson, J; Zhang, K; Filipovich AH; Bleesing, J; Marsh, RA. “Clinical flow cytometric screening of SAP and XIAP expression accurately identifies patients with SH2D1A and XIAP/BIRC4 mutations.” Cytometry B Clin Cytom. v. 86 p. 263-271.
