Collect

10-200 mg of STERILE chorionic villi, other fetal tissue or other tissue (or 1cm x 1cm or 2 mm punch biopsy), place in STERILE transport medium in STERILE leak-proof tubes.

Collection personnel MUST initial specimen container to confirm sample identity.

Minimum Collection Volume

25 mg of chorionic villi or other tissue in sterile culture medium is needed for 14 day turn around time (TAT).

or

1cm x 1cm or 2 mm punch biopsy in sterile culture medium.

If a lesser volume of chorionic villi or tissue is sent, the laboratory will attempt to perform the test requested.  The laboratory cannot assure either a result and/or the ability to perform repeat testing and/or additional testing if the minimum volumes are not met.

Stability (from collection to initiation)

Label tubes with patient name and date of birth (DOB).

Patient Preparation

For products of conception (POC) the preferred tissue is chorionic villi.  If fetal tissue is sent, please ALSO send chorionic villi, if available.

The lab can provide tubes of transport medium - Call (513) 636-4474.

DO NOT USE FORMALIN, the tissue must be fresh and sterile in order to obtain cell growth.

Storage/Transport Temperature

Store at room temperature (if storing overnight, please REFRIGERATE)  / Use overnight shipping (protect from temperature extremes, no ice) or call the lab for local courier service (contact laboratory prior to drawing specimen to ensure courier area coverage).

Performing Lab

Cytogenetics Laboratory (513) 636-4474  /  FAX: (513) 636-4373

Performed

6 AM - 12 AM (Monday through Friday, with more limited hours on the weekend)

Unacceptable Conditions

Specimen placed in formalin or non-sterile container.

Maternal decidua only in a POC sample.  If no fetal tissue is found upon initial specimen examination by laboratory staff, the ordering physician will be called. The decision whether or not to proceed with testing can be made at that time.

Synonyms

  • KARYOTYPE - PRODUCTS OF CONCEPTION CHROMOSOME STUDY
  • POC CHROMOSOME ANALYSIS
  • PRODUCTS OF CONCEPTION (POC) FETAL CHROMOSOME STUDY
  • 229 - CHROMOSOME ANALYSIS : PRODUCTS OF CONCEPTION
  • 231 - CHROMOSOME ANALYSIS : TISSUE

Methodology

Sterile tissue culture to obtain the required amount of cells for further testing.  If mutliple tissue types are sent the laboratory with set up each type under the same test accession number at no additional charge.

Reported

14 Days

Common Indications

RECURRENT MISCARRIAGE

CPT Codes

88233(X2),88262

Please call 1-866-450-4198 for pricing or with any billing questions.

Lab Use Only

NO FORMALIN - ROOM TEMP (MAY BE REFRIGERATED OVER-NIGHT) / CALL 6-4474 FOR PICKUP
Collection

Collect

10-200 mg of STERILE chorionic villi, other fetal tissue or other tissue (or 1cm x 1cm or 2 mm punch biopsy), place in STERILE transport medium in STERILE leak-proof tubes.

Collection personnel MUST initial specimen container to confirm sample identity.

Minimum Collection Volume

25 mg of chorionic villi or other tissue in sterile culture medium is needed for 14 day turn around time (TAT).

or

1cm x 1cm or 2 mm punch biopsy in sterile culture medium.

If a lesser volume of chorionic villi or tissue is sent, the laboratory will attempt to perform the test requested.  The laboratory cannot assure either a result and/or the ability to perform repeat testing and/or additional testing if the minimum volumes are not met.

Stability (from collection to initiation)

Label tubes with patient name and date of birth (DOB).

Patient Preparation

For products of conception (POC) the preferred tissue is chorionic villi.  If fetal tissue is sent, please ALSO send chorionic villi, if available.

The lab can provide tubes of transport medium - Call (513) 636-4474.

DO NOT USE FORMALIN, the tissue must be fresh and sterile in order to obtain cell growth.

Storage/Transport Temperature

Store at room temperature (if storing overnight, please REFRIGERATE)  / Use overnight shipping (protect from temperature extremes, no ice) or call the lab for local courier service (contact laboratory prior to drawing specimen to ensure courier area coverage).

Performing Lab

Cytogenetics Laboratory (513) 636-4474  /  FAX: (513) 636-4373

Performed

6 AM - 12 AM (Monday through Friday, with more limited hours on the weekend)

Unacceptable Conditions

Specimen placed in formalin or non-sterile container.

Maternal decidua only in a POC sample.  If no fetal tissue is found upon initial specimen examination by laboratory staff, the ordering physician will be called. The decision whether or not to proceed with testing can be made at that time.

Ordering

Synonyms

  • KARYOTYPE - PRODUCTS OF CONCEPTION CHROMOSOME STUDY
  • POC CHROMOSOME ANALYSIS
  • PRODUCTS OF CONCEPTION (POC) FETAL CHROMOSOME STUDY
  • 229 - CHROMOSOME ANALYSIS : PRODUCTS OF CONCEPTION
  • 231 - CHROMOSOME ANALYSIS : TISSUE

Methodology

Sterile tissue culture to obtain the required amount of cells for further testing.  If mutliple tissue types are sent the laboratory with set up each type under the same test accession number at no additional charge.

Reported

14 Days

Result Interpretation

Common Indications

RECURRENT MISCARRIAGE
Laboratory Personnel Use

CPT Codes

88233(X2),88262

Please call 1-866-450-4198 for pricing or with any billing questions.

Lab Use Only

NO FORMALIN - ROOM TEMP (MAY BE REFRIGERATED OVER-NIGHT) / CALL 6-4474 FOR PICKUP