Methodology

Molecular

Testing Schedule

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Report Availability

14 days

Minimum Volume

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Container

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Collect

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Special Instructions

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Clinical Utility

Panel targets known mutations which includes 63 genes associated with AML, MPN, CML, CMML, and JMML. This is a generic and comprehensive profiling of myeloid neoplasms.

Reference Range

Accompanies report

Includes

The test is performed by sequencing the entire coding regions of the genes listed. ABL1,ASXL1, ATRX,BCOR,BCORL1,BRAF,CALR,CBL,CBLB,CBLC,CDKN2A,CEBPA,CSF3R,CUX1,DDX41,DNMT3A, ETNK1,ETV6,EZH2,FBXW7,FLT3,GATA1,GATA2,GNAS,GNB1,HRAS,IDH1,IDH2,IKZF1,JAK2 including V617F and Exons 12+14, JAK3, KDM6A, KIT,KRAS ,MLL,MPL,MYD88, NF1,NOTCH1, NPM1,NRAS,PDGFRA,PHF6,PML,PPM1D,PTEN,PTPN11,RAD21,RUNX1,SETBP1,SF3B1,SH2B3, SMC1A,SMC3,SRSF2,STAG2,STAT3,STAT5B,TET2,TP53,U2AF1,WT1,ZRSR2. FLT3 is performed by multiple methods.

Clinical Utility

Panel targets known mutations which includes 63 genes associated with AML, MPN, CML, CMML, and JMML. This is a generic and comprehensive profiling of myeloid neoplasms.

Methodology

Molecular

Testing Schedule

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Report Availability

14 days

Collect

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Container

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Minimum Volume

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Special Instructions

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Reference Range

Accompanies report
Full View

Methodology

Molecular

Testing Schedule

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Report Availability

14 days

Minimum Volume

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Container

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Collect

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Special Instructions

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Clinical Utility

Panel targets known mutations which includes 63 genes associated with AML, MPN, CML, CMML, and JMML. This is a generic and comprehensive profiling of myeloid neoplasms.

Reference Range

Accompanies report

Includes

The test is performed by sequencing the entire coding regions of the genes listed. ABL1,ASXL1, ATRX,BCOR,BCORL1,BRAF,CALR,CBL,CBLB,CBLC,CDKN2A,CEBPA,CSF3R,CUX1,DDX41,DNMT3A, ETNK1,ETV6,EZH2,FBXW7,FLT3,GATA1,GATA2,GNAS,GNB1,HRAS,IDH1,IDH2,IKZF1,JAK2 including V617F and Exons 12+14, JAK3, KDM6A, KIT,KRAS ,MLL,MPL,MYD88, NF1,NOTCH1, NPM1,NRAS,PDGFRA,PHF6,PML,PPM1D,PTEN,PTPN11,RAD21,RUNX1,SETBP1,SF3B1,SH2B3, SMC1A,SMC3,SRSF2,STAG2,STAT3,STAT5B,TET2,TP53,U2AF1,WT1,ZRSR2. FLT3 is performed by multiple methods.
Overview

Clinical Utility

Panel targets known mutations which includes 63 genes associated with AML, MPN, CML, CMML, and JMML. This is a generic and comprehensive profiling of myeloid neoplasms.
Codes
Ordering Information

Methodology

Molecular

Testing Schedule

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday

Report Availability

14 days
Specimen Requirements

Collect

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Container

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Minimum Volume

Peripheral Blood: 5 mL in lavender top (EDTA) tube
Bone Marrow: 2 mL in lavender top (EDTA) tube
Paraffin embedded block or slides

Special Instructions

Specimens must be received on Fridays by 1600 in the Flow Cytometry Department
Do not collect on a Saturday or Sunday before a Monday holiday
Reference Range - Critical Values

Reference Range

Accompanies report