Whole blood or plasma on ice. Clotted sample. Sample collected in glass tube. Unspun specimen > 4 hrs old. Underfilled tube. Gross hemolysis.
Collection Comments
Full, 2.7mL Blue, BD 3.2% Na Citrate plastic tube. Do not send whole blood or plasma to lab on ice. Double spin and freeze plasma within 4 hrs of collection: Spin at 3000rpm for 15 min. Place top 2/3 of plasma in aliquot tube and spin aliquot at 3000 rpm for 15 min. Take top 2/3 of 2nd spin and put in another aliquot tube. Mark tube 'plasma'. Freeze immediately. Send frozen platelet poor plasma. Remember to properly label the aliquot tube with patient name, DOB, test and collect date.
Staclot LA is intended to specifically detect lupus anticoagulants, a type of antiphospholipid antibody. Lupus Anticoagulant assays based on different properties appear to be more or less sensitive to certain subgroups of LAs. Therefore at least two screening assays, based on different properties, should be performed before the possibility of LA is excluded. Borderline abnormal DRVVT and/or SCT samples should be tested with the Staclot LA assay.
Performed
Monday - Friday; Batched
Methodology
Semi-automated Clot Detection
Performing Lab
Special Coag
Synonyms
764
Staclot LA
Lupus Anticoaglulant Staclot (Confirmatory)
Hexagonal phase
Hexagonal Phospholipid Neutralization
Reference Interval
< 8.0 seconds
Interpretive Data
The presence of direct thrombin inhibitors, such as argatroban, dabigatran (Pradaxa), and bivalirudin (Angiomax), can affect results. There is lesser inhibition with the presence of direct Xa inhibitors, such as rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Savaysa).
False positive results can be seen in patients with high CRP levels.
Reference ranges are established using an adult population. Effect on the pediatric population reference range is uncertain.
Lupus Anticoagulant assays based on different properties appear to be more or less sensitive to certain subgroups of LAs. Therefore at least two screening assays, based on different properties, should be performed before the possibility of LA is excluded.
CPT Codes
85598
LOINC Codes
NAME
LOINC
Order
Staclot LA
33930-9
Result
Staclot LA
33930-9
Test Code (Outreach Synonym)
764
Catalog Code
3124795
Collection
Collect
Blood, Light Blue
Preferred Draw Volume
2.7 mL
Minimum Draw Volume
Full tube
Unacceptable Conditions
Whole blood or plasma on ice. Clotted sample. Sample collected in glass tube. Unspun specimen > 4 hrs old. Underfilled tube. Gross hemolysis.
Collection Comments
Full, 2.7mL Blue, BD 3.2% Na Citrate plastic tube. Do not send whole blood or plasma to lab on ice. Double spin and freeze plasma within 4 hrs of collection: Spin at 3000rpm for 15 min. Place top 2/3 of plasma in aliquot tube and spin aliquot at 3000 rpm for 15 min. Take top 2/3 of 2nd spin and put in another aliquot tube. Mark tube 'plasma'. Freeze immediately. Send frozen platelet poor plasma. Remember to properly label the aliquot tube with patient name, DOB, test and collect date.
Staclot LA is intended to specifically detect lupus anticoagulants, a type of antiphospholipid antibody. Lupus Anticoagulant assays based on different properties appear to be more or less sensitive to certain subgroups of LAs. Therefore at least two screening assays, based on different properties, should be performed before the possibility of LA is excluded. Borderline abnormal DRVVT and/or SCT samples should be tested with the Staclot LA assay.
Performed
Monday - Friday; Batched
Methodology
Semi-automated Clot Detection
Performing Lab
Special Coag
Synonyms
764
Staclot LA
Lupus Anticoaglulant Staclot (Confirmatory)
Hexagonal phase
Hexagonal Phospholipid Neutralization
Result Interpretation
Reference Interval
< 8.0 seconds
Interpretive Data
The presence of direct thrombin inhibitors, such as argatroban, dabigatran (Pradaxa), and bivalirudin (Angiomax), can affect results. There is lesser inhibition with the presence of direct Xa inhibitors, such as rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Savaysa).
False positive results can be seen in patients with high CRP levels.
Reference ranges are established using an adult population. Effect on the pediatric population reference range is uncertain.
Lupus Anticoagulant assays based on different properties appear to be more or less sensitive to certain subgroups of LAs. Therefore at least two screening assays, based on different properties, should be performed before the possibility of LA is excluded.
