Desired FISH probe and pertinent clinical diagnosis required with test order. Testing will not be performed until probe and diagnosis are provided; absence of this information will delay turnaround time.
Use to order individual or multiple oncology FISH probes if standard FISH panels are not desired.
Mnemonic
CHR FISHI
Epic Test Code
LAB002034
Synonyms
+10
+12
+15
+17
+4
+8
+9
11q23
12q31
13q13
14q32
18q11.2
18q21
19p13
1q21
20q Deletion (D20S108)
21q22
22q12.2
3q27
4q12
5q Deletion (EGR1)/Monosomy 5
5q32
5q33.1
7q Deletion(D7S486)/Monosomy 7
8p12
8q24
9p21
ABL1 Rearrangement
ABL2 Rearrangement
ATM Deletion
BCL6 Rearrangement
BCR-ABL1
C-Myc (MYC) Rearrangement
Cancer FISH
CBFB Rearrangement
CKS1B
CRLF2 Rearrangement
CSF1R Rearrangement
D13S319 Deletion
DDIT3 (CHOP)
del(11)(q22.3)
del(13)(q14.3)
del(17)(p13.1) (TP53) Deletion
del(20)(q12)
del(5)(q31)/-5
del(7)(q31)/-7
EGR1
EPOR Rearrangement
ETV6 Rearrangement
ETV6-RUNX1 (TEL-AML1 ) Fusion
EWSR1 Rearrangement
FGFR1 Rearrangement
FGFR1, 8p11-12
FKHR (FOXO1)
Hyperdiploidy with Trisomy 4, 10, and 17
IGH Rearrangement
IGH-BCL2 Fusion
IGH-CCND1 Fusion
IGH-FGFR3 Fusion
IGH-MAF Fusion
IGH-MAFB Fusion
IKZF1 (Ikaros) Deletion
inv(16)
inv(16)(p13.3q22)
inv(3)
JAK2 Rearrangement
KMT2A (MLL) Rearrangement
MALT1
oncology FISH
p16 (CDKN2) Deletion
PDGFR-alpha Rearrangement
PDGFR-beta Rearrangement
PDGFRA Rearrangement
PDGFRA-CHIC2-FIP1L1
PDGFRB Rearrangement
PDGFRB, 5q33.1
Philadelphia chromosome
PML-RARA Fusion
RPN1/MECOM (EVI1)
RUNX1 Rearrangement
RUNX1T1-RUNX1 (ETO-AML1) Fusion
SS18 (SYT) Rearrangement
t(11;14)(q13;q32)
t(12;21)(p13;q22)
t(14;16)(q32;q23.1)
t(14;18)(q32;q21)
t(14;20)(q32;q12)
t(15;17)(q24;q21)
t(3:3)
t(4;14)(p16;q32)
t(8;21)(q22;q22)
t(9;22)(q34;q11.2)
TCF3 (E2A) Rearrangement
TCL1 Rearrangement
TP53 (p53) Deletion
Trisomy 10
Trisomy 12
Trisomy 15
Trisomy 17
Trisomy 4
Trisomy 8
Trisomy 9
X and Y centromere (CEP X/Y)
NUP98 Rearrangement
CBFB-MYH11 Fusion, t(16;16)(p13.1;q22)
Methodology
Fluorescence in situ Hybridization (FISH)
Performed
Sun-Sat
Reported
3-10 days
CPT Codes
88271; 88275
Notes
Time required for testing can vary depending on specimen type and probes ordered.
Please indicate the names of probes needed for testing. Molecular Cytogenetics (FISH) Probe menu is available at https://www.aruplab.com/genetics/tests/fish-oncology Contact ARUP Genetics Processing at extension 3301 to add a probe to a current specimen.
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
Additional Technical Information
Time Sensitive
Oncology Test Request Form Recommended (ARUP form #43099)
Reference Interval
By report
LOINC
57802-1
11526-1
Performing Lab
ARUP Laboratories
Collection
Collect
Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Green (sodium heparin).
Specimen Preparation
Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL). OR transport 5 mL whole blood (Min: 2 mL)
Desired FISH probe and pertinent clinical diagnosis required with test order. Testing will not be performed until probe and diagnosis are provided; absence of this information will delay turnaround time.
Use to order individual or multiple oncology FISH probes if standard FISH panels are not desired.
Mnemonic
CHR FISHI
Epic Test Code
LAB002034
Synonyms
+10
+12
+15
+17
+4
+8
+9
11q23
12q31
13q13
14q32
18q11.2
18q21
19p13
1q21
20q Deletion (D20S108)
21q22
22q12.2
3q27
4q12
5q Deletion (EGR1)/Monosomy 5
5q32
5q33.1
7q Deletion(D7S486)/Monosomy 7
8p12
8q24
9p21
ABL1 Rearrangement
ABL2 Rearrangement
ATM Deletion
BCL6 Rearrangement
BCR-ABL1
C-Myc (MYC) Rearrangement
Cancer FISH
CBFB Rearrangement
CKS1B
CRLF2 Rearrangement
CSF1R Rearrangement
D13S319 Deletion
DDIT3 (CHOP)
del(11)(q22.3)
del(13)(q14.3)
del(17)(p13.1) (TP53) Deletion
del(20)(q12)
del(5)(q31)/-5
del(7)(q31)/-7
EGR1
EPOR Rearrangement
ETV6 Rearrangement
ETV6-RUNX1 (TEL-AML1 ) Fusion
EWSR1 Rearrangement
FGFR1 Rearrangement
FGFR1, 8p11-12
FKHR (FOXO1)
Hyperdiploidy with Trisomy 4, 10, and 17
IGH Rearrangement
IGH-BCL2 Fusion
IGH-CCND1 Fusion
IGH-FGFR3 Fusion
IGH-MAF Fusion
IGH-MAFB Fusion
IKZF1 (Ikaros) Deletion
inv(16)
inv(16)(p13.3q22)
inv(3)
JAK2 Rearrangement
KMT2A (MLL) Rearrangement
MALT1
oncology FISH
p16 (CDKN2) Deletion
PDGFR-alpha Rearrangement
PDGFR-beta Rearrangement
PDGFRA Rearrangement
PDGFRA-CHIC2-FIP1L1
PDGFRB Rearrangement
PDGFRB, 5q33.1
Philadelphia chromosome
PML-RARA Fusion
RPN1/MECOM (EVI1)
RUNX1 Rearrangement
RUNX1T1-RUNX1 (ETO-AML1) Fusion
SS18 (SYT) Rearrangement
t(11;14)(q13;q32)
t(12;21)(p13;q22)
t(14;16)(q32;q23.1)
t(14;18)(q32;q21)
t(14;20)(q32;q12)
t(15;17)(q24;q21)
t(3:3)
t(4;14)(p16;q32)
t(8;21)(q22;q22)
t(9;22)(q34;q11.2)
TCF3 (E2A) Rearrangement
TCL1 Rearrangement
TP53 (p53) Deletion
Trisomy 10
Trisomy 12
Trisomy 15
Trisomy 17
Trisomy 4
Trisomy 8
Trisomy 9
X and Y centromere (CEP X/Y)
NUP98 Rearrangement
CBFB-MYH11 Fusion, t(16;16)(p13.1;q22)
Methodology
Fluorescence in situ Hybridization (FISH)
Performed
Sun-Sat
Reported
3-10 days
CPT Codes
88271; 88275
Notes
Time required for testing can vary depending on specimen type and probes ordered.
Please indicate the names of probes needed for testing. Molecular Cytogenetics (FISH) Probe menu is available at https://www.aruplab.com/genetics/tests/fish-oncology Contact ARUP Genetics Processing at extension 3301 to add a probe to a current specimen.
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
Additional Technical Information
Time Sensitive
Oncology Test Request Form Recommended (ARUP form #43099)
Laboratories.