Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 6 mL Green tube (Sodium heparin), No Gel 3 mL-6 mL Preferred

Container Image

Outpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

Unacceptable Conditions

Wrong collection tube, Wrong type of specimen, Serum sample, Clotted specimen, Frozen specimen, Centrifuged specimen

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Remarks

If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Genetic Test Requisition Form is required. If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. When ordering this test, please provide following information on the test requisition form: 1) Previously-tested Child's Name (Proband's Name), 2) Proband's Date of Birth, 3) Proband's Test Accession Number, and 4) Chromosome locus requested for testing.

Please collect whole blood in Sodium Heparin tube (green-top tube without gel separator). DO NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Submission of a NaHep blood sample from the previously-tested child (proband) is required to be used as a positive control sample to provide the most accurate interpretation for the parental FISH result (no extra charge for proband sample processing/testing, except phlebotomy charge).
 

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

3 weeks

Lab Area

Institute for Genomic Medicine

Methodology

Fluorescence in situ hybridization (FISH)

CPT Codes

88230, 88271, 88273

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 6 mL Green tube (Sodium heparin), No Gel 3 mL-6 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 6 mL Green tube (Sodium heparin), No Gel 2 mL

Container Image

Inpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

Unacceptable Conditions

Wrong collection tube, Wrong type of specimen, Serum sample, Clotted specimen, Frozen specimen, Centrifuged specimen

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Remarks

If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Genetic Test Requisition Form is required. If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. When ordering this test, please provide following information on the test requisition form: 1) Previously-tested Child's Name (Proband's Name), 2) Proband's Date of Birth, 3) Proband's Test Accession Number, and 4) Chromosome locus requested for testing.

Please collect whole blood in Sodium Heparin tube (green-top tube without gel separator). DO NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Submission of a NaHep blood sample from the previously-tested child (proband) is required to be used as a positive control sample to provide the most accurate interpretation for the parental FISH result (no extra charge for proband sample processing/testing, except phlebotomy charge).
 

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

3 weeks

CPT Codes

88230, 88271, 88273

Lab Area

Institute for Genomic Medicine

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

Estimated Patient Price

$1,000 - $2,500

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

CPT Codes

88230, 88271, 88273

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Methodology

Fluorescence in situ hybridization (FISH)

Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 6 mL Green tube (Sodium heparin), No Gel 3 mL-6 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 6 mL Green tube (Sodium heparin), No Gel 2 mL

Container Image

Inpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

Outpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

InLab Processing

Send to Cytogenetics Lab with all submitted paperwork. CPA needs to order GENSP in Sunquest for Non-EPIC lab order.

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Unacceptable Conditions

Wrong collection tube, Wrong type of specimen, Serum sample, Clotted specimen, Frozen specimen, Centrifuged specimen

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

3 weeks

Remarks

If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Genetic Test Requisition Form is required. If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. When ordering this test, please provide following information on the test requisition form: 1) Previously-tested Child's Name (Proband's Name), 2) Proband's Date of Birth, 3) Proband's Test Accession Number, and 4) Chromosome locus requested for testing.

Please collect whole blood in Sodium Heparin tube (green-top tube without gel separator). DO NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Submission of a NaHep blood sample from the previously-tested child (proband) is required to be used as a positive control sample to provide the most accurate interpretation for the parental FISH result (no extra charge for proband sample processing/testing, except phlebotomy charge).
 

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

Methodology

Fluorescence in situ hybridization (FISH)

CPT Codes

88230, 88271, 88273

Estimated Patient Price

$1,000 - $2,500

DC Code

5321

Downtime Availability

4-Not available
Outpatient Requirements

Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 6 mL Green tube (Sodium heparin), No Gel 3 mL-6 mL Preferred

Container Image

Outpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

Unacceptable Conditions

Wrong collection tube, Wrong type of specimen, Serum sample, Clotted specimen, Frozen specimen, Centrifuged specimen

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Remarks

If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Genetic Test Requisition Form is required. If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. When ordering this test, please provide following information on the test requisition form: 1) Previously-tested Child's Name (Proband's Name), 2) Proband's Date of Birth, 3) Proband's Test Accession Number, and 4) Chromosome locus requested for testing.

Please collect whole blood in Sodium Heparin tube (green-top tube without gel separator). DO NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Submission of a NaHep blood sample from the previously-tested child (proband) is required to be used as a positive control sample to provide the most accurate interpretation for the parental FISH result (no extra charge for proband sample processing/testing, except phlebotomy charge).
 

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

3 weeks

Lab Area

Institute for Genomic Medicine

Methodology

Fluorescence in situ hybridization (FISH)

CPT Codes

88230, 88271, 88273

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test
Inpatient Requirements

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 6 mL Green tube (Sodium heparin), No Gel 3 mL-6 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 6 mL Green tube (Sodium heparin), No Gel 2 mL

Container Image

Inpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

Unacceptable Conditions

Wrong collection tube, Wrong type of specimen, Serum sample, Clotted specimen, Frozen specimen, Centrifuged specimen

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Remarks

If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Genetic Test Requisition Form is required. If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. When ordering this test, please provide following information on the test requisition form: 1) Previously-tested Child's Name (Proband's Name), 2) Proband's Date of Birth, 3) Proband's Test Accession Number, and 4) Chromosome locus requested for testing.

Please collect whole blood in Sodium Heparin tube (green-top tube without gel separator). DO NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Submission of a NaHep blood sample from the previously-tested child (proband) is required to be used as a positive control sample to provide the most accurate interpretation for the parental FISH result (no extra charge for proband sample processing/testing, except phlebotomy charge).
 

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

3 weeks

CPT Codes

88230, 88271, 88273

Lab Area

Institute for Genomic Medicine

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

Estimated Patient Price

$1,000 - $2,500
Overview/Billing

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

CPT Codes

88230, 88271, 88273
Interpretation

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Methodology

Fluorescence in situ hybridization (FISH)
NCH Lab Only

Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 6 mL Green tube (Sodium heparin), No Gel 3 mL-6 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 6 mL Green tube (Sodium heparin), No Gel 2 mL

Container Image

Inpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

Outpatient Specimen Preparation

Whole blood: Do not centrifuge
                      Do not freeze
                      Keep at room temperature

InLab Processing

Send to Cytogenetics Lab with all submitted paperwork. CPA needs to order GENSP in Sunquest for Non-EPIC lab order.

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Unacceptable Conditions

Wrong collection tube, Wrong type of specimen, Serum sample, Clotted specimen, Frozen specimen, Centrifuged specimen

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

3 weeks

Remarks

If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Genetic Test Requisition Form is required. If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. When ordering this test, please provide following information on the test requisition form: 1) Previously-tested Child's Name (Proband's Name), 2) Proband's Date of Birth, 3) Proband's Test Accession Number, and 4) Chromosome locus requested for testing.

Please collect whole blood in Sodium Heparin tube (green-top tube without gel separator). DO NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Submission of a NaHep blood sample from the previously-tested child (proband) is required to be used as a positive control sample to provide the most accurate interpretation for the parental FISH result (no extra charge for proband sample processing/testing, except phlebotomy charge).
 

Clinical Information

This test is available for biological parents (mother and father) of a proband who previously had a cytogenetic abnormality detected by Nationwide Children's Laboratory, such as a balanced or unbalanced chromosome rearrangement detected by chromosome analysis or FISH analysis, or a genomic gain or loss detected by microarray analysis. If the proband's cytogenetic abnormality was detected by an outside laboratory or if the patient to be tested is a family member of, but not biological parents of, the proband (e.g. grandparent, sibling, aunt/uncle, cousin, etc.), then please order a test called "FISH Analysis Only (test code: FISHON)" in place of this test.

Depending on the chromosome loci to be tested, special FISH probes may need to be ordered, which may result in longer result turn-around-time.

PLEASE NOTE: Small cytogenetic abnormalities below certain size may not be detectable by FISH analysis. If there are any questions regarding whether the proband's cytogenetic abnormality is detectable by FISH analysis or not, please call the Cytogenetic Laboratory (614) 722-5321 and ask to speak with a laboratory genetic counselor.

Synonyms

  • FISH analysis on parental sample, Parental follow-up FISH, Parental FISH test for known cytogenetic finding, IGM Test

Methodology

Fluorescence in situ hybridization (FISH)

CPT Codes

88230, 88271, 88273

Estimated Patient Price

$1,000 - $2,500

DC Code

5321

Downtime Availability

4-Not available

Lab Area

Lab Area
Institute for Genomic Medicine