Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred
Bone marrow 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred

Container Image

Outpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                            Do not centrifuge
                                            Keep at room temperature or refrigerate
 

Unacceptable Conditions

Centrifuged specimen, Clotted specimen, Wrong collection tube

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Bone marrow: Room temperature 24 hour(s)
Bone marrow: Refrigerated 72 hour(s)
 

Remarks

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. Submission of BOTH the Recipient and Donor samples are required for this test. Please collect recipient sample PRIOR to pre-transplant treatment. For donor samples, please label with two unique donor idenfiers such as donor name and donor DOB, or two ID numbers associated wtih the donor if anonymous donor from the donor registry is used.  If the donor sample is submitted separately from the recipient sample, please submit the donor sample accompanied by the requisition form completed with both the donor and recipient information. All samples should be labeled with specimen type (e.g. blood, bone marrow, stem cells). Please provide expected date of transplant on the requisition from. 

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

2 weeks

Lab Area

Institute for Genomic Medicine

Methodology

Polymerase chain reaction (PCR), Capillary electrophoresis, Microsatellite marker analysis , DNA extraction

CPT Codes

81265 (81266 added when there is more than one donor)

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred
Bone marrow 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 4 mL Purple tube (EDTA) 3 mL
Bone marrow 4 mL Purple tube (EDTA) 3 mL

Container Image

Inpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                             Do not centrifuge
                                             Keep at room temperature or refrigerate
 

Unacceptable Conditions

Centrifuged specimen, Clotted specimen, Wrong collection tube

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Bone marrow: Room temperature 24 hour(s)
Bone marrow: Refrigerated 72 hour(s)
 

Remarks

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. Submission of BOTH the Recipient and Donor samples are required for this test. Please collect recipient sample PRIOR to pre-transplant treatment. For donor samples, please label with two unique donor idenfiers such as donor name and donor DOB, or two ID numbers associated wtih the donor if anonymous donor from the donor registry is used.  If the donor sample is submitted separately from the recipient sample, please submit the donor sample accompanied by the requisition form completed with both the donor and recipient information. All samples should be labeled with specimen type (e.g. blood, bone marrow, stem cells). Please provide expected date of transplant on the requisition from. 

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

2 weeks

CPT Codes

81265 (81266 added when there is more than one donor)

Lab Area

Institute for Genomic Medicine

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

Estimated Patient Price

$1,000 - $2,500

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

CPT Codes

81265 (81266 added when there is more than one donor)

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Methodology

Polymerase chain reaction (PCR), Capillary electrophoresis, Microsatellite marker analysis , DNA extraction

Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred
Bone marrow 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 4 mL Purple tube (EDTA) 3 mL
Bone marrow 4 mL Purple tube (EDTA) 3 mL

Container Image

Inpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                             Do not centrifuge
                                             Keep at room temperature or refrigerate
 

Outpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                            Do not centrifuge
                                            Keep at room temperature or refrigerate
 

InLab Processing

Send to Molecular Genetics Lab with all submitted paperwork. CPA needs to order GENSP in Sunquest for Non-EPIC lab order.

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Bone marrow: Room temperature 24 hour(s)
Bone marrow: Refrigerated 72 hour(s)
 

Unacceptable Conditions

Centrifuged specimen, Clotted specimen, Wrong collection tube

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

2 weeks

Remarks

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. Submission of BOTH the Recipient and Donor samples are required for this test. Please collect recipient sample PRIOR to pre-transplant treatment. For donor samples, please label with two unique donor idenfiers such as donor name and donor DOB, or two ID numbers associated wtih the donor if anonymous donor from the donor registry is used.  If the donor sample is submitted separately from the recipient sample, please submit the donor sample accompanied by the requisition form completed with both the donor and recipient information. All samples should be labeled with specimen type (e.g. blood, bone marrow, stem cells). Please provide expected date of transplant on the requisition from. 

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

Methodology

Polymerase chain reaction (PCR), Capillary electrophoresis, Microsatellite marker analysis , DNA extraction

CPT Codes

81265 (81266 added when there is more than one donor)

Estimated Patient Price

$1,000 - $2,500

DC Code

5321

Downtime Availability

4-Not available
Outpatient Requirements

Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred
Bone marrow 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred

Container Image

Outpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                            Do not centrifuge
                                            Keep at room temperature or refrigerate
 

Unacceptable Conditions

Centrifuged specimen, Clotted specimen, Wrong collection tube

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Bone marrow: Room temperature 24 hour(s)
Bone marrow: Refrigerated 72 hour(s)
 

Remarks

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. Submission of BOTH the Recipient and Donor samples are required for this test. Please collect recipient sample PRIOR to pre-transplant treatment. For donor samples, please label with two unique donor idenfiers such as donor name and donor DOB, or two ID numbers associated wtih the donor if anonymous donor from the donor registry is used.  If the donor sample is submitted separately from the recipient sample, please submit the donor sample accompanied by the requisition form completed with both the donor and recipient information. All samples should be labeled with specimen type (e.g. blood, bone marrow, stem cells). Please provide expected date of transplant on the requisition from. 

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

2 weeks

Lab Area

Institute for Genomic Medicine

Methodology

Polymerase chain reaction (PCR), Capillary electrophoresis, Microsatellite marker analysis , DNA extraction

CPT Codes

81265 (81266 added when there is more than one donor)

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test
Inpatient Requirements

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred
Bone marrow 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 4 mL Purple tube (EDTA) 3 mL
Bone marrow 4 mL Purple tube (EDTA) 3 mL

Container Image

Inpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                             Do not centrifuge
                                             Keep at room temperature or refrigerate
 

Unacceptable Conditions

Centrifuged specimen, Clotted specimen, Wrong collection tube

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Bone marrow: Room temperature 24 hour(s)
Bone marrow: Refrigerated 72 hour(s)
 

Remarks

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. Submission of BOTH the Recipient and Donor samples are required for this test. Please collect recipient sample PRIOR to pre-transplant treatment. For donor samples, please label with two unique donor idenfiers such as donor name and donor DOB, or two ID numbers associated wtih the donor if anonymous donor from the donor registry is used.  If the donor sample is submitted separately from the recipient sample, please submit the donor sample accompanied by the requisition form completed with both the donor and recipient information. All samples should be labeled with specimen type (e.g. blood, bone marrow, stem cells). Please provide expected date of transplant on the requisition from. 

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

2 weeks

CPT Codes

81265 (81266 added when there is more than one donor)

Lab Area

Institute for Genomic Medicine

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

Estimated Patient Price

$1,000 - $2,500
Overview/Billing

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

CPT Codes

81265 (81266 added when there is more than one donor)
Interpretation

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Methodology

Polymerase chain reaction (PCR), Capillary electrophoresis, Microsatellite marker analysis , DNA extraction
NCH Lab Only

Outpatient Submit with Specimen

Collect

Specimen Type Type of Container Volume of Specimen Status
Whole blood 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred
Bone marrow 4 mL Purple tube (EDTA) 4 mL-8 mL Preferred

Minimum Volume

Specimen Type Type of Container Minimum Volume
Whole blood 4 mL Purple tube (EDTA) 3 mL
Bone marrow 4 mL Purple tube (EDTA) 3 mL

Container Image

Inpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                             Do not centrifuge
                                             Keep at room temperature or refrigerate
 

Outpatient Specimen Preparation

Whole blood,Bone marrow: Do not freeze
                                            Do not centrifuge
                                            Keep at room temperature or refrigerate
 

InLab Processing

Send to Molecular Genetics Lab with all submitted paperwork. CPA needs to order GENSP in Sunquest for Non-EPIC lab order.

Stability

Whole blood: Room temperature 24 hour(s)
Whole blood: Refrigerated 72 hour(s)

Bone marrow: Room temperature 24 hour(s)
Bone marrow: Refrigerated 72 hour(s)
 

Unacceptable Conditions

Centrifuged specimen, Clotted specimen, Wrong collection tube

Days Performed

Monday through Saturday

Set Up Schedule

All tests not performed daily.

Typical Turnaround

2 weeks

Remarks

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. Submission of BOTH the Recipient and Donor samples are required for this test. Please collect recipient sample PRIOR to pre-transplant treatment. For donor samples, please label with two unique donor idenfiers such as donor name and donor DOB, or two ID numbers associated wtih the donor if anonymous donor from the donor registry is used.  If the donor sample is submitted separately from the recipient sample, please submit the donor sample accompanied by the requisition form completed with both the donor and recipient information. All samples should be labeled with specimen type (e.g. blood, bone marrow, stem cells). Please provide expected date of transplant on the requisition from. 

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Clinical Information

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers has become the standard technique for engraftment analysis due to its high sensitivity. Pre-transplant bone marrow engraftment analysis determines the polymorphic genetic markers in the recpieint and donor samples, so these genotypes will be available after the transplant for post-transplant engraftment analysis to be done on patient sample. Therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-5321 with questions.

Synonyms

  • Chimerism testing, Chimerism study, Pre transplant, Pre-BMT DNA markers, Pre-BMT DNA typing, Pre-BMT donor recipient genotyping, Bone marrow transplant, BMT, HSCT pre-transplant, Stem cell transplant, IGM Test

Methodology

Polymerase chain reaction (PCR), Capillary electrophoresis, Microsatellite marker analysis , DNA extraction

CPT Codes

81265 (81266 added when there is more than one donor)

Estimated Patient Price

$1,000 - $2,500

DC Code

5321

Downtime Availability

4-Not available

Lab Area

Lab Area
Institute for Genomic Medicine