| Specimen Type | Type of Container | Volume of Specimen | Status |
|---|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | 50 mg | Preferred |
| Tissue (Snap-frozen) | Cryogenic tube | 50 mg | Alternate |
| Bone marrow | 6 mL Purple tube (EDTA) | 3 mL-5 mL | Preferred |
| OCT-embedded tissue | Tissue cassette | Preferred | |
| OCT-embedded tissue | Cryogenic tube | Alternate | |
| Paraffin embedded tissue | Paraffin block | Preferred | |
| Tissue (Fresh) | Tissue culture transport media | 50 mg | Preferred |
| Tissue (Fresh) | Sterile container with saline | 50 mg | Alternate |
| Tissue scrolls (FFPE) | Sterile container | Preferred |
If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Oncology Genetic Test Requisition Form is required. Please send all samples via overnight delivery. Saturday deliveries are accepted; please check Saturday Delivery on shipment label. For questions, please call (614) 722-5321.
If submitting tissue scroll specimen, please use this Tissue Scroll Calculator tool to determine the thickness and number of tissue scrolls to send to the laboratory.
A minimum of 20% tumor cellularity must be present in the submitted sample (based on internal pathology review) for accurate reporting of somatic variants. Testing will not be carried out on samples with <20% tumor.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
| Specimen Type | Type of Container | Volume of Specimen | Status |
|---|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | 50 mg | Preferred |
| Tissue (Snap-frozen) | Cryogenic tube | 50 mg | Alternate |
| Bone marrow | 6 mL Purple tube (EDTA) | 3 mL-5 mL | Preferred |
| OCT-embedded tissue | Tissue cassette | Preferred | |
| OCT-embedded tissue | Cryogenic tube | Alternate | |
| Paraffin embedded tissue | Paraffin block | Preferred | |
| Tissue (Fresh) | Tissue culture transport media | 50 mg | Preferred |
| Tissue (Fresh) | Sterile container with saline | 50 mg | Alternate |
| Tissue scrolls (FFPE) | Sterile container | Preferred |
| Specimen Type | Type of Container | Minimum Volume |
|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | |
| Tissue (Snap-frozen) | Cryogenic tube | |
| Bone marrow | 6 mL Purple tube (EDTA) | 2 mL |
| OCT-embedded tissue | Tissue cassette | |
| OCT-embedded tissue | Cryogenic tube | |
| Paraffin embedded tissue | Paraffin block | |
| Tissue (Fresh) | Tissue culture transport media | |
| Tissue (Fresh) | Sterile container with saline | |
| Tissue scrolls (FFPE) | Sterile container |
If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Oncology Genetic Test Requisition Form is required. Please send all samples via overnight delivery. Saturday deliveries are accepted; please check Saturday Delivery on shipment label. For questions, please call (614) 722-5321.
If submitting tissue scroll specimen, please use this Tissue Scroll Calculator tool to determine the thickness and number of tissue scrolls to send to the laboratory.
A minimum of 20% tumor cellularity must be present in the submitted sample (based on internal pathology review) for accurate reporting of somatic variants. Testing will not be carried out on samples with <20% tumor.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
| Specimen Type | Type of Container | Volume of Specimen | Status |
|---|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | 50 mg | Preferred |
| Tissue (Snap-frozen) | Cryogenic tube | 50 mg | Alternate |
| Bone marrow | 6 mL Purple tube (EDTA) | 3 mL-5 mL | Preferred |
| OCT-embedded tissue | Tissue cassette | Preferred | |
| OCT-embedded tissue | Cryogenic tube | Alternate | |
| Paraffin embedded tissue | Paraffin block | Preferred | |
| Tissue (Fresh) | Tissue culture transport media | 50 mg | Preferred |
| Tissue (Fresh) | Sterile container with saline | 50 mg | Alternate |
| Tissue scrolls (FFPE) | Sterile container | Preferred |
| Specimen Type | Type of Container | Minimum Volume |
|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | |
| Tissue (Snap-frozen) | Cryogenic tube | |
| Bone marrow | 6 mL Purple tube (EDTA) | 2 mL |
| OCT-embedded tissue | Tissue cassette | |
| OCT-embedded tissue | Cryogenic tube | |
| Paraffin embedded tissue | Paraffin block | |
| Tissue (Fresh) | Tissue culture transport media | |
| Tissue (Fresh) | Sterile container with saline | |
| Tissue scrolls (FFPE) | Sterile container |
If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Oncology Genetic Test Requisition Form is required. Please send all samples via overnight delivery. Saturday deliveries are accepted; please check Saturday Delivery on shipment label. For questions, please call (614) 722-5321.
If submitting tissue scroll specimen, please use this Tissue Scroll Calculator tool to determine the thickness and number of tissue scrolls to send to the laboratory.
A minimum of 20% tumor cellularity must be present in the submitted sample (based on internal pathology review) for accurate reporting of somatic variants. Testing will not be carried out on samples with <20% tumor.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
| Outpatient Requirements |
| Specimen Type | Type of Container | Volume of Specimen | Status |
|---|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | 50 mg | Preferred |
| Tissue (Snap-frozen) | Cryogenic tube | 50 mg | Alternate |
| Bone marrow | 6 mL Purple tube (EDTA) | 3 mL-5 mL | Preferred |
| OCT-embedded tissue | Tissue cassette | Preferred | |
| OCT-embedded tissue | Cryogenic tube | Alternate | |
| Paraffin embedded tissue | Paraffin block | Preferred | |
| Tissue (Fresh) | Tissue culture transport media | 50 mg | Preferred |
| Tissue (Fresh) | Sterile container with saline | 50 mg | Alternate |
| Tissue scrolls (FFPE) | Sterile container | Preferred |
If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Oncology Genetic Test Requisition Form is required. Please send all samples via overnight delivery. Saturday deliveries are accepted; please check Saturday Delivery on shipment label. For questions, please call (614) 722-5321.
If submitting tissue scroll specimen, please use this Tissue Scroll Calculator tool to determine the thickness and number of tissue scrolls to send to the laboratory.
A minimum of 20% tumor cellularity must be present in the submitted sample (based on internal pathology review) for accurate reporting of somatic variants. Testing will not be carried out on samples with <20% tumor.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
| Inpatient Requirements |
| Specimen Type | Type of Container | Volume of Specimen | Status |
|---|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | 50 mg | Preferred |
| Tissue (Snap-frozen) | Cryogenic tube | 50 mg | Alternate |
| Bone marrow | 6 mL Purple tube (EDTA) | 3 mL-5 mL | Preferred |
| OCT-embedded tissue | Tissue cassette | Preferred | |
| OCT-embedded tissue | Cryogenic tube | Alternate | |
| Paraffin embedded tissue | Paraffin block | Preferred | |
| Tissue (Fresh) | Tissue culture transport media | 50 mg | Preferred |
| Tissue (Fresh) | Sterile container with saline | 50 mg | Alternate |
| Tissue scrolls (FFPE) | Sterile container | Preferred |
| Specimen Type | Type of Container | Minimum Volume |
|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | |
| Tissue (Snap-frozen) | Cryogenic tube | |
| Bone marrow | 6 mL Purple tube (EDTA) | 2 mL |
| OCT-embedded tissue | Tissue cassette | |
| OCT-embedded tissue | Cryogenic tube | |
| Paraffin embedded tissue | Paraffin block | |
| Tissue (Fresh) | Tissue culture transport media | |
| Tissue (Fresh) | Sterile container with saline | |
| Tissue scrolls (FFPE) | Sterile container |
If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Oncology Genetic Test Requisition Form is required. Please send all samples via overnight delivery. Saturday deliveries are accepted; please check Saturday Delivery on shipment label. For questions, please call (614) 722-5321.
If submitting tissue scroll specimen, please use this Tissue Scroll Calculator tool to determine the thickness and number of tissue scrolls to send to the laboratory.
A minimum of 20% tumor cellularity must be present in the submitted sample (based on internal pathology review) for accurate reporting of somatic variants. Testing will not be carried out on samples with <20% tumor.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
| Overview/Billing |
| Interpretation |
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
| NCH Lab Only |
| Specimen Type | Type of Container | Volume of Specimen | Status |
|---|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | 50 mg | Preferred |
| Tissue (Snap-frozen) | Cryogenic tube | 50 mg | Alternate |
| Bone marrow | 6 mL Purple tube (EDTA) | 3 mL-5 mL | Preferred |
| OCT-embedded tissue | Tissue cassette | Preferred | |
| OCT-embedded tissue | Cryogenic tube | Alternate | |
| Paraffin embedded tissue | Paraffin block | Preferred | |
| Tissue (Fresh) | Tissue culture transport media | 50 mg | Preferred |
| Tissue (Fresh) | Sterile container with saline | 50 mg | Alternate |
| Tissue scrolls (FFPE) | Sterile container | Preferred |
| Specimen Type | Type of Container | Minimum Volume |
|---|---|---|
| Tissue (Snap-frozen) | Tissue cassette | |
| Tissue (Snap-frozen) | Cryogenic tube | |
| Bone marrow | 6 mL Purple tube (EDTA) | 2 mL |
| OCT-embedded tissue | Tissue cassette | |
| OCT-embedded tissue | Cryogenic tube | |
| Paraffin embedded tissue | Paraffin block | |
| Tissue (Fresh) | Tissue culture transport media | |
| Tissue (Fresh) | Sterile container with saline | |
| Tissue scrolls (FFPE) | Sterile container |
If you are an internal ordering provider with access to Nationwide Children’s Epic system, no requisition form is required; please place the lab order electronically in Epic. If you are an external healthcare provider with no access to Nationwide Children’s Epic system, submission of a completed Oncology Genetic Test Requisition Form is required. Please send all samples via overnight delivery. Saturday deliveries are accepted; please check Saturday Delivery on shipment label. For questions, please call (614) 722-5321.
If submitting tissue scroll specimen, please use this Tissue Scroll Calculator tool to determine the thickness and number of tissue scrolls to send to the laboratory.
A minimum of 20% tumor cellularity must be present in the submitted sample (based on internal pathology review) for accurate reporting of somatic variants. Testing will not be carried out on samples with <20% tumor.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
This test includes targeted sequencing of the ALK, ATRX, BRAF, HRAS, KRAS, NRAS, PTPN11, and TP53 genes.
For variants reported as pathogenic, likely pathogenic, or unknown significance, a germline sample (buccal swab or uninvolved peripheral blood sample) may be submitted (additional charges apply). Please contact the laboratory directly for information.
