In order to perform this test, the recipient and the donor previously must have had a "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)" performed by the Nationwide Children's Laboratory to determine the informative DNA markers in the recipient and donor. 

Please note: if the patient has had a CTL infusion within the last 3 months, please contact the IGM Genetic counselors to discuss testing needs before ordering Bone Marrow Engraftment Post-Transplant analysis. 

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. The requisition form must provide transplant date and donor information including two unique identifiers associated with the donor, such as donor name and donor DOB, or two ID numbers associated with the donor if anonymous donor from the donor registry is used. This test is available for patients with transplant history involving one or two donors; this test cannot be performed for patients with transplant history involving three or more donors.  All samples should be labeled with specimen type (e.g. blood, bone marrow). 

SORTED CELLS ORDERING: 

• Please see XSORT entry for further additional information on sorted cells. 

If analysis of sorted cells is requested, please indicate on the Test Requisition Form:

• Whether testing is being performed on whole blood and/or bone marrow, and which types of sorted cells are requested (CD3/CD33 vs. CD3/CD33/CD19/CD56).

SORTED CELLS SAMPLE COLLECTION:

For post-transplant chimerism analysis by XX/XY FISH, please see test code CHIMFISH (Post-Transplant Analysis by FISH). Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-3280 with questions.

This is a DNA-based (molecular genetic) test that quantitatively evaluates polymorphic genetic markers present in the sample. Post-transplant recipient genotypes will be compared to pre-transplant recipient and donor genotypes previously determined by "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)."

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers, such as this test, has become the standard technique for engraftment analysis due to its high sensitivity.

In order to perform this test, the recipient and the donor previously must have had a "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)" performed by the Nationwide Children's Laboratory to determine the informative DNA markers in the recipient and donor. 

Please note: if the patient has had a CTL infusion within the last 3 months, please contact the IGM Genetic counselors to discuss testing needs before ordering Bone Marrow Engraftment Post-Transplant analysis. 

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. The requisition form must provide transplant date and donor information including two unique identifiers associated with the donor, such as donor name and donor DOB, or two ID numbers associated with the donor if anonymous donor from the donor registry is used. This test is available for patients with transplant history involving one or two donors; this test cannot be performed for patients with transplant history involving three or more donors.  All samples should be labeled with specimen type (e.g. blood, bone marrow). 

SORTED CELLS ORDERING: 

• Please see XSORT entry for further additional information on sorted cells. 

If analysis of sorted cells is requested, please indicate on the Test Requisition Form:

• Whether testing is being performed on whole blood and/or bone marrow, and which types of sorted cells are requested (CD3/CD33 vs. CD3/CD33/CD19/CD56).

SORTED CELLS SAMPLE COLLECTION:

For post-transplant chimerism analysis by XX/XY FISH, please see test code CHIMFISH (Post-Transplant Analysis by FISH). Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-3280 with questions.

This is a DNA-based (molecular genetic) test that quantitatively evaluates polymorphic genetic markers present in the sample. Post-transplant recipient genotypes will be compared to pre-transplant recipient and donor genotypes previously determined by "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)."

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers, such as this test, has become the standard technique for engraftment analysis due to its high sensitivity.

This is a DNA-based (molecular genetic) test that quantitatively evaluates polymorphic genetic markers present in the sample. Post-transplant recipient genotypes will be compared to pre-transplant recipient and donor genotypes previously determined by "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)."

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers, such as this test, has become the standard technique for engraftment analysis due to its high sensitivity.

In order to perform this test, the recipient and the donor previously must have had a "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)" performed by the Nationwide Children's Laboratory to determine the informative DNA markers in the recipient and donor. 

Please note: if the patient has had a CTL infusion within the last 3 months, please contact the IGM Genetic counselors to discuss testing needs before ordering Bone Marrow Engraftment Post-Transplant analysis. 

Submission of a completed BMT Engraftment/Chimerism Test Requisition Form is required. The requisition form must provide transplant date and donor information including two unique identifiers associated with the donor, such as donor name and donor DOB, or two ID numbers associated with the donor if anonymous donor from the donor registry is used. This test is available for patients with transplant history involving one or two donors; this test cannot be performed for patients with transplant history involving three or more donors.  All samples should be labeled with specimen type (e.g. blood, bone marrow). 

SORTED CELLS ORDERING: 

• Please see XSORT entry for further additional information on sorted cells. 

If analysis of sorted cells is requested, please indicate on the Test Requisition Form:

• Whether testing is being performed on whole blood and/or bone marrow, and which types of sorted cells are requested (CD3/CD33 vs. CD3/CD33/CD19/CD56).

SORTED CELLS SAMPLE COLLECTION:

For post-transplant chimerism analysis by XX/XY FISH, please see test code CHIMFISH (Post-Transplant Analysis by FISH). Please call the Institute for Genetics Medicine Clinical Laboratory at (614) 722-3280 with questions.

This is a DNA-based (molecular genetic) test that quantitatively evaluates polymorphic genetic markers present in the sample. Post-transplant recipient genotypes will be compared to pre-transplant recipient and donor genotypes previously determined by "Bone Marrow Engraftment Pre-Transplant Analysis (Test Code: BMPR)."

Bone marrow engraftment analysis, also known as chimerism testing, involves determining the percentage of donor cells present in the recipient sample after allogeneic bone marrow transplant (BMT) or hematopoietic stem cell transplant (HSCT). Engraftment monitoring after BMT/HSCT is critical to assess the outcome of transplant and to predict the risk of relapse. Quantitative analysis of polymorphic genetic markers, such as this test, has become the standard technique for engraftment analysis due to its high sensitivity.