Collect

Respiratory specimens, CSF, pleural fluid, or tissue.

Specimen Preparation

Unprocessed Specimens: Transport 5-10 mL respiratory specimen, CSF or pleural fluid (Min: 1 mL) in a sterile container, or tissue large enough to be ground. Label as unprocessed.
Processed Specimens: Transport 2-5 mL digested/decontaminated respiratory specimen, CSF, pleural fluid, or tissue in a sterile container. (Min: 1 mL)
Place each specimen in an individually sealed bag.

Unacceptable Conditions

Blood, paraffin blocks, stool, swabs, and urine.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Unprocessed: Ambient: 3 days; Refrigerated: 1 week; Frozen: 1 month 
Processed
: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month

Performed

Sun-Sat

Remarks

Specimen source required. Processed Specimens: Identify method used for digestion and provide smear results.

Notes

Body fluids other than pleural fluid will be run with a disclaimer.

Specimen source required. To perform this test, it is essential to know whether or not the submitted specimen has been processed (digestion and decontamination procedure). If processed, smear results must be provided as a comment on the test order or requisition. Delayed turnaround time will occur if the required information is not provided.

After a positive result, repeat orders for Mycobacterium tuberculosis Complex Detection and Rifampin Resistance by PCR will continue to yield a positive result and repeat testing is not clinically indicated.

The Xpert MTB/RIF test performance has not been evaluated with samples from pediatric patients.

Referral Lab

Ordering Recommendations

Panel includes PCR testing to detect M. tuberculosis complex isolates and determine possible resistance to rifampin treatment. Test may be ordered for client-processed specimens. Refer to specimen requirements.

Performed

Sun-Sat

Methodology

Qualitative Polymerase Chain Reaction (PCR)

Reported

1-3 days

Synonyms

  • MC MTD
  • MC MTDCSF
  • MTB PCR
  • MTD PCR

ARUP Test Code

2010775

Interpretive Data

Mycobacterial culture is a more sensitive method than molecular testing for the diagnosis of tuberculosis and is still considered the gold standard. When possible, a culture must be performed regardless of the molecular method test result.

CPT Codes

87556; 87798

LOINC

  • 31208-2
  • 38379-4
  • 89372-7
  • 93479-4

ARUP Test Code

2010775

Performing Lab

ARUP Laboratories

Test Build Information

Order Code Order Name Result Code Result Name LOINC CPT
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR RIFSRC MTBRIF SOURCE 31208-2 87556, 87798
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR MTBPCR MYCOBACTERIA TUBERCULOSIS 13956-8  
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR RIFPCR MTB RIFAMPIN PCR 46244-0  
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR MTBINT MTB COMPLEX INTERP 48767-8  

AOE Information (Ask at Order Entry Questions)

AOE    
Result Code Result Name LOINC
RIFSRC MTBRIF SOURCE 31208-2
Collection

Collect

Respiratory specimens, CSF, pleural fluid, or tissue.

Specimen Preparation

Unprocessed Specimens: Transport 5-10 mL respiratory specimen, CSF or pleural fluid (Min: 1 mL) in a sterile container, or tissue large enough to be ground. Label as unprocessed.
Processed Specimens: Transport 2-5 mL digested/decontaminated respiratory specimen, CSF, pleural fluid, or tissue in a sterile container. (Min: 1 mL)
Place each specimen in an individually sealed bag.

Unacceptable Conditions

Blood, paraffin blocks, stool, swabs, and urine.

Storage/Transport Temperature

Refrigerated.

Stability (from collection to initiation)

Unprocessed: Ambient: 3 days; Refrigerated: 1 week; Frozen: 1 month 
Processed
: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month

Performed

Sun-Sat

Remarks

Specimen source required. Processed Specimens: Identify method used for digestion and provide smear results.

Notes

Body fluids other than pleural fluid will be run with a disclaimer.

Specimen source required. To perform this test, it is essential to know whether or not the submitted specimen has been processed (digestion and decontamination procedure). If processed, smear results must be provided as a comment on the test order or requisition. Delayed turnaround time will occur if the required information is not provided.

After a positive result, repeat orders for Mycobacterium tuberculosis Complex Detection and Rifampin Resistance by PCR will continue to yield a positive result and repeat testing is not clinically indicated.

The Xpert MTB/RIF test performance has not been evaluated with samples from pediatric patients.

Referral Lab

Ordering

Ordering Recommendations

Panel includes PCR testing to detect M. tuberculosis complex isolates and determine possible resistance to rifampin treatment. Test may be ordered for client-processed specimens. Refer to specimen requirements.

Performed

Sun-Sat

Methodology

Qualitative Polymerase Chain Reaction (PCR)

Reported

1-3 days

Synonyms

  • MC MTD
  • MC MTDCSF
  • MTB PCR
  • MTD PCR

ARUP Test Code

2010775
Result Interpretation

Interpretive Data

Mycobacterial culture is a more sensitive method than molecular testing for the diagnosis of tuberculosis and is still considered the gold standard. When possible, a culture must be performed regardless of the molecular method test result.

Administrative

CPT Codes

87556; 87798

LOINC

  • 31208-2
  • 38379-4
  • 89372-7
  • 93479-4

ARUP Test Code

2010775

Performing Lab

ARUP Laboratories
RPS Interface Information

Test Build Information

Order Code Order Name Result Code Result Name LOINC CPT
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR RIFSRC MTBRIF SOURCE 31208-2 87556, 87798
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR MTBPCR MYCOBACTERIA TUBERCULOSIS 13956-8  
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR RIFPCR MTB RIFAMPIN PCR 46244-0  
MTBRIF MTB DETECT & RIFAMPIN RESIST PCR MTBINT MTB COMPLEX INTERP 48767-8  

AOE Information (Ask at Order Entry Questions)

AOE    
Result Code Result Name LOINC
RIFSRC MTBRIF SOURCE 31208-2