10 mL ACD (Yellow) tube (whole blood).
or
5mL EDTA (lav) tube.
Minimum 5mL.
Unacceptable Conditions
Specimens drawn in Heparin
Storage/Transport Temperature
Room Temperature
Performed
Molecular Diagnostics/Tissue Typing
Notes
Over 90% of patients with celiac disease express HLA DQ2 and the remainder express DQ8. The HLA DQ2 and DQ8 alleles are associated with increased genetic susceptibility for celiac disease.
The frequency of celiac risk genotypes in the general population is about 30%, whereas only 1 to 3% actually develops disease. Associations of DQ2 and/or DQ8 with irritable bowel syndrome have also been reported.
Performed
Molecular Diagnostics/Tissue Typing
Methodology
DNA amplification and Liquid Bead array detection
Reported
Mon-Fri 0800-1630. Turnaround time 5 days.
Reference Interval
Negative
CPT Codes
81376
Collection
Collect
10 mL ACD (Yellow) tube (whole blood).
or
5mL EDTA (lav) tube.
Minimum 5mL.
Unacceptable Conditions
Specimens drawn in Heparin
Storage/Transport Temperature
Room Temperature
Performed
Molecular Diagnostics/Tissue Typing
Notes
Over 90% of patients with celiac disease express HLA DQ2 and the remainder express DQ8. The HLA DQ2 and DQ8 alleles are associated with increased genetic susceptibility for celiac disease.
The frequency of celiac risk genotypes in the general population is about 30%, whereas only 1 to 3% actually develops disease. Associations of DQ2 and/or DQ8 with irritable bowel syndrome have also been reported.
