Any specimen other than whole blood preserved in EDTA.
Stability (from collection to initiation)
Ambient: 72 hours
Refrigerated 2-8oC: 7 days
Absolute Minimum
0.5mL whole blood
If only one sample is submitted for a CBC and a HbA1c, please run the CBC first, then send the sample to Specialtty Testing Center for the HbA1c.
Reference Interval
3.9% - 5.6%
Interpretive Data
5.7% - 6.4% indicates increased risk for diabetes
> 6.5% is a criterion for the diagnosis of diabetes
HbA1c levels are proportional to the average glucose concentration in the blood and the lifespan of hemoglobin in the circulation, which is preferable to a single glucose determination. It is considered an objective test of metabolic control which is independent of patients' cooperation, time of day, and insulin. Boronate affinity HbA1c method provides accurate analytical results in the presence of most hemoglobin variants. Patients with >15% Hb F may yield falsely decreased HbA1c results.
The estimated fasting Glucose (eAg) will be reported as a calculation, because values may be used for the management and screening of Diabetes Mellitus.
The estimated average glucose (eAG) calculation is based on hemoglobin A1c and glucose results from the ADAG study.
eAG = (Hgb A1c x 28.7) - 46.7
The eAG study has not been validated in children or pregnant women. Also, eAG values are not valid for patients with hemoglobinopathies, anemia, and altered erythrocyte turnover as evidenced by blood loss, transfusions, chronic renal or liver disease, or for patients on high-dose vitamin C or erythropoietin treatments.
Abnormal red cell survival, such as hemolytic anemias, may yield results that do not reflect the patient's true glycemic state. Also, samples from polycythemic or post-splenectomy patients may have increased glycosylated hemoglobin values which do not reflect the patient's true glycemic state. Patients with >15% Hg F may yield a falsely decreased HbA1c result.
Standardization for this test is based on NGSP. The NGSP values relate to IFCC values by the following master equation:
Any specimen other than whole blood preserved in EDTA.
Stability (from collection to initiation)
Ambient: 72 hours
Refrigerated 2-8oC: 7 days
Absolute Minimum
0.5mL whole blood
If only one sample is submitted for a CBC and a HbA1c, please run the CBC first, then send the sample to Specialtty Testing Center for the HbA1c.
Result Interpretation
Reference Interval
3.9% - 5.6%
Interpretive Data
5.7% - 6.4% indicates increased risk for diabetes
> 6.5% is a criterion for the diagnosis of diabetes
HbA1c levels are proportional to the average glucose concentration in the blood and the lifespan of hemoglobin in the circulation, which is preferable to a single glucose determination. It is considered an objective test of metabolic control which is independent of patients' cooperation, time of day, and insulin. Boronate affinity HbA1c method provides accurate analytical results in the presence of most hemoglobin variants. Patients with >15% Hb F may yield falsely decreased HbA1c results.
The estimated fasting Glucose (eAg) will be reported as a calculation, because values may be used for the management and screening of Diabetes Mellitus.
The estimated average glucose (eAG) calculation is based on hemoglobin A1c and glucose results from the ADAG study.
eAG = (Hgb A1c x 28.7) - 46.7
The eAG study has not been validated in children or pregnant women. Also, eAG values are not valid for patients with hemoglobinopathies, anemia, and altered erythrocyte turnover as evidenced by blood loss, transfusions, chronic renal or liver disease, or for patients on high-dose vitamin C or erythropoietin treatments.
Abnormal red cell survival, such as hemolytic anemias, may yield results that do not reflect the patient's true glycemic state. Also, samples from polycythemic or post-splenectomy patients may have increased glycosylated hemoglobin values which do not reflect the patient's true glycemic state. Patients with >15% Hg F may yield a falsely decreased HbA1c result.
Standardization for this test is based on NGSP. The NGSP values relate to IFCC values by the following master equation:
