Ordering Recommendations

Use to diagnose patients for mucopolysaccharidosis type I (also known as MPS I, Hurler, Scheie, and Hurler-Scheie syndromes). To screen for all types of MPS, refer to Mucopolysaccharides Screen - Electrophoresis & Quantitation, Urine (0081352). To monitor glycosaminoglycans (GAGs) in patients previously diagnosed with MPS, refer to Mucopolysaccharides, Quantitative, Urine (0081357).

Performed

Varies

Methodology

Quantitative Fluorometry

Reported

3-10 days

Synonyms

  • ALPHA-L-IDURONIDASE,BLOOD (ALPHA-IDURONIDASE ENZYME ACTIVITY)
  • Mucopolysaccharidosis Type I
  • Scheie
  • Hunter
  • Hunter-Scheie

Performing Lab

ARUP

Collect

Yellow (ACD Solution B), Lavender (K2EDTA), or Lavender (K3EDTA).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Room Temperature  (Preferred) or Refrigerated

Unacceptable Conditions

Grossly hemolyzed or heparinized specimens.

Stability (from collection to initiation)

Ambient: 3 days; Refrigerated: 3 days; Frozen: Unacceptable

Remarks

Additional information is required: Clinical Indication for testing.

Reference Interval

12 - 65 nmol hydrolyzed/hr/mg protein

Interpretive Data

Refer to report.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

CPT Codes

82657

Label Name

SENDM - enter test name, ARUP # 2011415, specimen type

Ordering

Ordering Recommendations

Use to diagnose patients for mucopolysaccharidosis type I (also known as MPS I, Hurler, Scheie, and Hurler-Scheie syndromes). To screen for all types of MPS, refer to Mucopolysaccharides Screen - Electrophoresis & Quantitation, Urine (0081352). To monitor glycosaminoglycans (GAGs) in patients previously diagnosed with MPS, refer to Mucopolysaccharides, Quantitative, Urine (0081357).

Performed

Varies

Methodology

Quantitative Fluorometry

Reported

3-10 days

Synonyms

  • ALPHA-L-IDURONIDASE,BLOOD (ALPHA-IDURONIDASE ENZYME ACTIVITY)
  • Mucopolysaccharidosis Type I
  • Scheie
  • Hunter
  • Hunter-Scheie

Performing Lab

ARUP

Collection

Collect

Yellow (ACD Solution B), Lavender (K2EDTA), or Lavender (K3EDTA).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Room Temperature  (Preferred) or Refrigerated

Unacceptable Conditions

Grossly hemolyzed or heparinized specimens.

Stability (from collection to initiation)

Ambient: 3 days; Refrigerated: 3 days; Frozen: Unacceptable

Remarks

Additional information is required: Clinical Indication for testing.
Result Interpretation

Reference Interval

12 - 65 nmol hydrolyzed/hr/mg protein

Interpretive Data

Refer to report.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Administrative

CPT Codes

82657

Label Name

SENDM - enter test name, ARUP # 2011415, specimen type