UCHealth University of Colorado Hospital Clinical Laboratory - Molecular Diagnostics
Collect
Rectal swab using COPAN Transystem™ 139C (LQ Stuart Dual Swab). Do not use any other swab type. New admissions—Contact Molecular (x86892) for the swab. All others—Infection Control will distribute these swabs to floors.
Insert both swab tips approximately 1 cm beyond the anal sphincter and rotate gently. Discard white cap. Place specimen swabs in the transport tube and firmly push the red cap to completely seal.
Do not break swab at break point or remove swabs from red cap.
Unacceptable Conditions
Sources other than rectal swabs.
Samples not submitted in COPAN Transystem™ 139C (Dual Swab in Stuarts Media).
Highly soiled swabs.
Refrigerated or frozen swabs.
Test not approved by Infection Prevention, Microbiology Medical Directors (non-system/clients exempt), or triggered through admission.
Sample not properly identified, incorrect container, or past stability.
Storage/Transport Temperature
Ambient
Performed
Daily
Stability (from collection to initiation)
Room Temp: 5 days Refrigerated: Unacceptable Frozen: Unacceptable
Remarks
This test is intended as an aid for infection control to monitor the spread of carabapenem non-susceptible organisms in healthcare settings.
Ordering limitations apply.
Performed
Daily
Methodology
Qualitative Real-time PCR using Cepheid® GeneXpert®
Reported
Same day
Synonyms
CPO PCR
LAB8920
Carbapenemase Producing Organism PCR
EPIC Code
CPO PCR
Reference Interval
IMP
Not detected
VIM
Not detected
NDM
Not detected
KPC
Not detected
OXA48
Not detected
Interpretive Data
Interpretation: Not detected = Specific mutation not identified in isolate. Detected = Specific mutation identified in isolate.
Methodology: This real-time assay utilizes the Cepheid Xpert Carba-R assay. A "Detected" result should be coupled with clinical indicators for diagnosis. A "Not detected" result for this assay does not exclude the presence of other resistance mechanisms. This test has been approved by the U.S. Food and Drug Administration for testing rectal isolates. This test is not intended to guide or monitor treatment but rather as an infection control tool. This laboratory is certified under the Clinical Laboratory Improvement Amendment of 1988 ("CLIA") as qualified to perform high complexity clinical testing.
Collection
EPIC Code
CPO PCR
Performing Lab
UCHealth University of Colorado Hospital Clinical Laboratory - Molecular Diagnostics
Collect
Rectal swab using COPAN Transystem™ 139C (LQ Stuart Dual Swab). Do not use any other swab type. New admissions—Contact Molecular (x86892) for the swab. All others—Infection Control will distribute these swabs to floors.
Insert both swab tips approximately 1 cm beyond the anal sphincter and rotate gently. Discard white cap. Place specimen swabs in the transport tube and firmly push the red cap to completely seal.
Do not break swab at break point or remove swabs from red cap.
Unacceptable Conditions
Sources other than rectal swabs.
Samples not submitted in COPAN Transystem™ 139C (Dual Swab in Stuarts Media).
Highly soiled swabs.
Refrigerated or frozen swabs.
Test not approved by Infection Prevention, Microbiology Medical Directors (non-system/clients exempt), or triggered through admission.
Sample not properly identified, incorrect container, or past stability.
Storage/Transport Temperature
Ambient
Performed
Daily
Stability (from collection to initiation)
Room Temp: 5 days Refrigerated: Unacceptable Frozen: Unacceptable
Remarks
This test is intended as an aid for infection control to monitor the spread of carabapenem non-susceptible organisms in healthcare settings.
Ordering limitations apply.
Ordering
Performed
Daily
Methodology
Qualitative Real-time PCR using Cepheid® GeneXpert®
Reported
Same day
Synonyms
CPO PCR
LAB8920
Carbapenemase Producing Organism PCR
EPIC Code
CPO PCR
Result Interpretation
Reference Interval
IMP
Not detected
VIM
Not detected
NDM
Not detected
KPC
Not detected
OXA48
Not detected
Interpretive Data
Interpretation: Not detected = Specific mutation not identified in isolate. Detected = Specific mutation identified in isolate.
Methodology: This real-time assay utilizes the Cepheid Xpert Carba-R assay. A "Detected" result should be coupled with clinical indicators for diagnosis. A "Not detected" result for this assay does not exclude the presence of other resistance mechanisms. This test has been approved by the U.S. Food and Drug Administration for testing rectal isolates. This test is not intended to guide or monitor treatment but rather as an infection control tool. This laboratory is certified under the Clinical Laboratory Improvement Amendment of 1988 ("CLIA") as qualified to perform high complexity clinical testing.
