Blood: Specimen should be a dedicated tube (no tube sharing with other labs or add-on testing). Test sample must be collected at Vanderbilt. Outside samples will not be accepted. (Min 0.5mL whole blood)
Buccal: Collect 4 swabs per patient/order. Please click on the following link to see detailed buccal swab collection instructions: Click Here for Buccal Swab Collection Guide
Pediatric Collection
N/A
Preferred Collection Volume
4mL whole blood
Alternate Specimen
N/A
Patient Preparation
Call the Molecular Diagnostics Laboratory at 615-343-8121 if additional assistance is needed regarding specimen requirements or submission or if patient has received a transfusion in the prior 2 weeks.
Specimen
Whole blood or tissue
Reasons for Rejection
Client will be notified by Molecular Diagnostics Lab if specimen is rejected. Externally extracted DNA received for clinical testing will only be accepted from CLIA-certified laboratories or laboratories meeting equivalent requirements.
Blood: Ambient (15-25°C) or Refrigerated (2-8°C); Buccal: Ambient (15-25°C)
Synonyms
LAB6342VML
LAB6342-VML
LAB6342, PREDICT
Performed
Variable
Resulting Laboratory
Vanderbilt Medical Laboratories
Turn Around Time
7 days
Ordering Indicators
Used to assess genetic risk of abnormal drug absorption, distribution, metabolism or excretion for drugs by genotyping for common variants in CYP2C19, CYP2C9, VKORC1, CYP3A5, CYP4F2, CYP2D6, TPMT, SLCO1B1, NUDT15 and DPYD as well CYP2D6 copy number determination. May aid in drug selection and dose planning for many drugs and in avoiding an adverse drug response
Interpretive Data
Results from this assay may indicate dosage adjustments or medication alternatives that should be considered. Additional information regarding the implications of results is available at www.mydruggenome.org.
Reference Interval
Not established for this test
Additional Information
Laboratory Developed Test
Methodology
Variant analysis using Taqman® SNP genotyping assay
Section
Molecular Diagnostics Laboratory
Patient Preparation
Call the Molecular Diagnostics Laboratory at 615-343-8121 if additional assistance is needed regarding specimen requirements or submission or if patient has received a transfusion in the prior 2 weeks.
Blood: Specimen should be a dedicated tube (no tube sharing with other labs or add-on testing). Test sample must be collected at Vanderbilt. Outside samples will not be accepted. (Min 0.5mL whole blood)
Buccal: Collect 4 swabs per patient/order. Please click on the following link to see detailed buccal swab collection instructions: Click Here for Buccal Swab Collection Guide
Pediatric Collection
N/A
Storage/Transport Temperature
Blood: Ambient (15-25°C) or Refrigerated (2-8°C); Buccal: Ambient (15-25°C)
Used to assess genetic risk of abnormal drug absorption, distribution, metabolism or excretion for drugs by genotyping for common variants in CYP2C19, CYP2C9, VKORC1, CYP3A5, CYP4F2, CYP2D6, TPMT, SLCO1B1, NUDT15 and DPYD as well CYP2D6 copy number determination. May aid in drug selection and dose planning for many drugs and in avoiding an adverse drug response
Synonyms
LAB6342, PREDICT
LAB6342-VML
LAB6342VML
Performed
Variable
Turn Around Time
7 days
Methodology
Variant analysis using Taqman® SNP genotyping assay
Results from this assay may indicate dosage adjustments or medication alternatives that should be considered. Additional information regarding the implications of results is available at www.mydruggenome.org.
Methodology
Variant analysis using Taqman® SNP genotyping assay
Blood: Specimen should be a dedicated tube (no tube sharing with other labs or add-on testing). Test sample must be collected at Vanderbilt. Outside samples will not be accepted. (Min 0.5mL whole blood)
Buccal: Collect 4 swabs per patient/order. Please click on the following link to see detailed buccal swab collection instructions: Click Here for Buccal Swab Collection Guide
Pediatric Collection
N/A
Preferred Collection Volume
4mL whole blood
Alternate Specimen
N/A
Patient Preparation
Call the Molecular Diagnostics Laboratory at 615-343-8121 if additional assistance is needed regarding specimen requirements or submission or if patient has received a transfusion in the prior 2 weeks.
Specimen
Whole blood or tissue
Reasons for Rejection
Client will be notified by Molecular Diagnostics Lab if specimen is rejected. Externally extracted DNA received for clinical testing will only be accepted from CLIA-certified laboratories or laboratories meeting equivalent requirements.
Blood: Ambient (15-25°C) or Refrigerated (2-8°C); Buccal: Ambient (15-25°C)
Synonyms
LAB6342VML
LAB6342-VML
LAB6342, PREDICT
Performed
Variable
Resulting Laboratory
Vanderbilt Medical Laboratories
Turn Around Time
7 days
Ordering Indicators
Used to assess genetic risk of abnormal drug absorption, distribution, metabolism or excretion for drugs by genotyping for common variants in CYP2C19, CYP2C9, VKORC1, CYP3A5, CYP4F2, CYP2D6, TPMT, SLCO1B1, NUDT15 and DPYD as well CYP2D6 copy number determination. May aid in drug selection and dose planning for many drugs and in avoiding an adverse drug response
Interpretive Data
Results from this assay may indicate dosage adjustments or medication alternatives that should be considered. Additional information regarding the implications of results is available at www.mydruggenome.org.
Reference Interval
Not established for this test
Additional Information
Laboratory Developed Test
Methodology
Variant analysis using Taqman® SNP genotyping assay
Section
Molecular Diagnostics Laboratory
Specimen Requirements
Patient Preparation
Call the Molecular Diagnostics Laboratory at 615-343-8121 if additional assistance is needed regarding specimen requirements or submission or if patient has received a transfusion in the prior 2 weeks.
Blood: Specimen should be a dedicated tube (no tube sharing with other labs or add-on testing). Test sample must be collected at Vanderbilt. Outside samples will not be accepted. (Min 0.5mL whole blood)
Buccal: Collect 4 swabs per patient/order. Please click on the following link to see detailed buccal swab collection instructions: Click Here for Buccal Swab Collection Guide
Pediatric Collection
N/A
Storage/Transport Temperature
Blood: Ambient (15-25°C) or Refrigerated (2-8°C); Buccal: Ambient (15-25°C)
Used to assess genetic risk of abnormal drug absorption, distribution, metabolism or excretion for drugs by genotyping for common variants in CYP2C19, CYP2C9, VKORC1, CYP3A5, CYP4F2, CYP2D6, TPMT, SLCO1B1, NUDT15 and DPYD as well CYP2D6 copy number determination. May aid in drug selection and dose planning for many drugs and in avoiding an adverse drug response
Synonyms
LAB6342, PREDICT
LAB6342-VML
LAB6342VML
Performed
Variable
Turn Around Time
7 days
Methodology
Variant analysis using Taqman® SNP genotyping assay
Results from this assay may indicate dosage adjustments or medication alternatives that should be considered. Additional information regarding the implications of results is available at www.mydruggenome.org.
Methodology
Variant analysis using Taqman® SNP genotyping assay
