Collect

Collect 2 Gold SST containers, allowing the blood to fill to the fill-line.

Preferred Container

2 Gold - SST Container with gel

Preferred Collection Volume

6.0 mL whole blood

Specimen Preparation

Mix by inversion.  Specimen should be centrifuged and separated from cells within 45 minutes of collection, with a minimum of 3 mL serum aliquotted into send-out container.

Offsite Collection Instructions

Mix by inversion.  Specimen should be centrifuged and separated from cells within 45 minutes of collection, with a minimum of 3 mL serum aliquotted into send-out container.  Transport frozen on dry ice.

Stability (from collection to initiation)

Room temperature - 7 days, refrigerated - 7 days, frozen - 2 years

Required Testing Volume

3.0 mL serum

Minimum Volume

3 mL serum

Storage/Transport Temperature

Transport immediately to laboratory at room temperature.  

Shipping

Frozen

Preferred Specimen Source

serum

Referral Lab

Labcorp 500108 (Endocrine Sciences)

Turn Around Time

8 - 12 days

Performing Lab

Labcorp (Endocrine Sciences)

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Synonyms

  • ESDIES
  • Estradiol (Esoterix)
  • Estradiol (Postmenopausal)
  • Estradiol (Pediatric Sendout)

Reference Interval

 
Age Range (pg/mL)
Newborn Levels are markedly elevated at birth and fall rapidly during the first week to prepubertal values of <15
Male <6 months Levels increase to 10 - 32 between 30 and 60 days, then decline to prepubertal levels of <15 by six months.
Female <1 year Levels increase to 5.0 - 50 between 30 and 60 days, then decline to prepubertal levels of <15 during the first year.
Prepubertal  <15
Puberty
Tanner Stage Age (years) Male Range (pg/mL)
1 <9.8 5.0 - 11
2 9.8 - 14.5 5.0 - 16
3 10.7 - 15.4 5.0 - 25
4 11.8 - 16.2 10 - 36
5 12.8 - 17.3 10 - 36
Tanner Stage Age (years) Female Range (pg/ml)
1 <9.2 5.0 - 20
2 9.2 - 13.7 10 - 24
3 10.0 - 14.4 7.0 - 60
4 10.7 - 15.6 21 - 85
5 11.8 - 18.6 34 - 170
Age Range (pg/mL)
Adult males 8.0 - 35
Adult females Range (pg/mL)
Follicular 30 - 100
Luteal 70 - 300
Postmenopausal <15

CPT Codes

82670

Laboratory Department

Send Outs
Collection

Collect

Collect 2 Gold SST containers, allowing the blood to fill to the fill-line.

Preferred Container

2 Gold - SST Container with gel

Preferred Collection Volume

6.0 mL whole blood

Specimen Preparation

Mix by inversion.  Specimen should be centrifuged and separated from cells within 45 minutes of collection, with a minimum of 3 mL serum aliquotted into send-out container.

Offsite Collection Instructions

Mix by inversion.  Specimen should be centrifuged and separated from cells within 45 minutes of collection, with a minimum of 3 mL serum aliquotted into send-out container.  Transport frozen on dry ice.

Stability (from collection to initiation)

Room temperature - 7 days, refrigerated - 7 days, frozen - 2 years

Required Testing Volume

3.0 mL serum

Minimum Volume

3 mL serum

Storage/Transport Temperature

Transport immediately to laboratory at room temperature.  

Shipping

Frozen

Preferred Specimen Source

serum

Referral Lab

Labcorp 500108 (Endocrine Sciences)
Ordering

Turn Around Time

8 - 12 days

Performing Lab

Labcorp (Endocrine Sciences)

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Synonyms

  • ESDIES
  • Estradiol (Esoterix)
  • Estradiol (Postmenopausal)
  • Estradiol (Pediatric Sendout)
Result Interpretation

Reference Interval

 
Age Range (pg/mL)
Newborn Levels are markedly elevated at birth and fall rapidly during the first week to prepubertal values of <15
Male <6 months Levels increase to 10 - 32 between 30 and 60 days, then decline to prepubertal levels of <15 by six months.
Female <1 year Levels increase to 5.0 - 50 between 30 and 60 days, then decline to prepubertal levels of <15 during the first year.
Prepubertal  <15
Puberty
Tanner Stage Age (years) Male Range (pg/mL)
1 <9.8 5.0 - 11
2 9.8 - 14.5 5.0 - 16
3 10.7 - 15.4 5.0 - 25
4 11.8 - 16.2 10 - 36
5 12.8 - 17.3 10 - 36
Tanner Stage Age (years) Female Range (pg/ml)
1 <9.2 5.0 - 20
2 9.2 - 13.7 10 - 24
3 10.0 - 14.4 7.0 - 60
4 10.7 - 15.6 21 - 85
5 11.8 - 18.6 34 - 170
Age Range (pg/mL)
Adult males 8.0 - 35
Adult females Range (pg/mL)
Follicular 30 - 100
Luteal 70 - 300
Postmenopausal <15
Administrative

CPT Codes

82670

Laboratory Department

Send Outs

Important Testing Information

Testing Notes
Testing Indicated for:
  • Pediatric
  • Postmenopausal Females
  • Adult Males
  • Individuals on Estrogen-Suppressing hormone Therapy

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