Use this mass spectrometry test to measure a wide range of estradiol concentrations. Most useful when low estradiol concentrations are expected, regardless of the patient’s sex assigned at birth. Use to monitor estradiol in individuals on estrogen-suppressing hormone therapies (eg, aromatase inhibitors or testosterone).To compare this test to other estrogen tests, refer to the ARUP Estrogen Tests Comparison table.
Collection Container
Collect
Serum separator tube, lavender (EDTA), pink (K2EDTA) or green (sodium or lithium heparin).
Specimen Preparation
Separate serum or plasma from cells within 2 hours after collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL) Indicate age and sex of patient on test request form AND specimen tube.
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month
Premenopausal Early Follicular: 30.0-100.0 Late Follicular: 100.0-400.0 Luteal: 50.0-150.0
Postmenopausal: 2.0-21.0
Tanner Stage I
Less than 8.0
Less than 56.0
Tanner Stage II
Less than 10.0
2.0-133.0
Tanner Stage III
1.0-35.0
12.0-277.0
Tanner Stage IV-V
3.0-35.0
2.0-259.0
Interpretive Data
For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0093247.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
CPT Codes
82670
LOINC
35384-7
ARUP Test Code
0093247
Collection & Processing
Ordering Recommendations
Use this mass spectrometry test to measure a wide range of estradiol concentrations. Most useful when low estradiol concentrations are expected, regardless of the patient’s sex assigned at birth. Use to monitor estradiol in individuals on estrogen-suppressing hormone therapies (eg, aromatase inhibitors or testosterone).To compare this test to other estrogen tests, refer to the ARUP Estrogen Tests Comparison table.
Collection Container
Collect
Serum separator tube, lavender (EDTA), pink (K2EDTA) or green (sodium or lithium heparin).
Specimen Preparation
Separate serum or plasma from cells within 2 hours after collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL) Indicate age and sex of patient on test request form AND specimen tube.
Storage/Transport Temperature
Refrigerated.
Stability (from collection to initiation)
After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month
Premenopausal Early Follicular: 30.0-100.0 Late Follicular: 100.0-400.0 Luteal: 50.0-150.0
Postmenopausal: 2.0-21.0
Tanner Stage I
Less than 8.0
Less than 56.0
Tanner Stage II
Less than 10.0
2.0-133.0
Tanner Stage III
1.0-35.0
12.0-277.0
Tanner Stage IV-V
3.0-35.0
2.0-259.0
Interpretive Data
For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0093247.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Testing Updates
Billing Codes
CPT Codes
82670
LOINC
35384-7
ARUP Test Code
0093247
Ordering Information
Cerner Orderable
Estradiol, TMS
Penn Chart Orderable
Estradiol by Tandem Mass Spectometry; ESTTMS
Performing Lab
ARUP
Performed
Sun-Sat
Reported
1-5 days
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Laboratories.