Ordering Recommendations

Assist in diagnosing acquired (idiopathic) or inherited thrombotic thrombocytopenic purpura (TTP).

Inpatient Approval Requirements

Call Coagulation Lab (215-662-3447) for test approval.

After Hours: Please call CP Resident Pager (215-306-0286) for test approval.

Collection Container

x 2

Collect

Citrated plasma, two (2) 2.7 mL citrated blue top tubes

Storage/Transport Temperature

Frozen platelet poor plasma

Stability (from collection to initiation)

Ambient: 2 Hours
For anything longer, please double spin and freeze

Unacceptable Conditions

QNS or clotted specimens; whole blood received >4 hours after being collected

Reference Interval

Greater than 60%

Interpretive Data and Information

ADAMTS13 levels of less than 10 percent may be associated with either inherited (Upshaw-Schulman Syndrome) or acquired thrombotic thrombocytopenic purpura (TTP).

A variety of medical conditions may result in a mild to moderate deficiency of ADAMTS13 activity. Recent plasma exchange therapy may raise the observed ADAMTS13 activity.

CPT Codes

85397

LOINC

  • 53622-7
Collection & Processing

Ordering Recommendations

Assist in diagnosing acquired (idiopathic) or inherited thrombotic thrombocytopenic purpura (TTP).

Inpatient Approval Requirements

Call Coagulation Lab (215-662-3447) for test approval.

After Hours: Please call CP Resident Pager (215-306-0286) for test approval.

Collection Container

x 2

Collect

Citrated plasma, two (2) 2.7 mL citrated blue top tubes

Storage/Transport Temperature

Frozen platelet poor plasma

Stability (from collection to initiation)

Ambient: 2 Hours
For anything longer, please double spin and freeze

Unacceptable Conditions

QNS or clotted specimens; whole blood received >4 hours after being collected
CR&P Information
Result Interpretation

Reference Interval

Greater than 60%

Interpretive Data and Information

ADAMTS13 levels of less than 10 percent may be associated with either inherited (Upshaw-Schulman Syndrome) or acquired thrombotic thrombocytopenic purpura (TTP).

A variety of medical conditions may result in a mild to moderate deficiency of ADAMTS13 activity. Recent plasma exchange therapy may raise the observed ADAMTS13 activity.
Testing Updates
Billing Codes

CPT Codes

85397

LOINC

  • 53622-7

Ordering Information

Cerner Orderable
ADAMTS13
Penn Chart Orderable
ADAMTS13
Performing Lab
Special Coagulation
Performed
Mon-Fri
Reported
24 Hours
Methodology
Chromogenic Assay
Synonyms
  • von Willebrand Factor Cleaving Protease
  • ATS-13

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