Ordering Recommendations

Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

Collect

Protease Inhibitor tube (PPACK; Phe-Pro-Arg-chloromethylketone) (ARUP supply #49662), available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at (800) 522-2787. A winged collection set must be used.

Specimen Container

Specimen Preparation

Mix well. Separate from cells within 1 hour of collection. Transfer 1.5 mL plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)

Storage/Transport Temperature

Frozen. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Grossly hemolyzed specimens.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months

Notes

Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

Referral Lab

Ordering Recommendations

Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

EPIC Order Code

LAB3911

Sunquest Code

PTHRPS

Reference Lab Number

2010677

Synonyms

  • Parathyroid Hormone Related Protein
  • Parathyroid Hormone Related Peptide
  • Humoral Hypercalcemia of Malignancy Factor
  • HHM
  • PTH-RP
  • PTH Related Protein
  • PTH Related Peptide
  • PRP
  • Parathyroid Related Protein
  • Parathyroid Related Polypeptide
  • PTHRP, Plasma
  • PTHrP secretion
  • LAB3911
  • PTHRPS

CPT Codes

82542

LOINC

  • 15087-0

Reference Lab Number

2010677

Reference Interval

AgeMale
Female
Under 18 yearsNot establishedNot established
18 years and older0.0-2.3 pmol/L0.0-3.4 pmol/L

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Collection

Ordering Recommendations

Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

Collect

Protease Inhibitor tube (PPACK; Phe-Pro-Arg-chloromethylketone) (ARUP supply #49662), available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at (800) 522-2787. A winged collection set must be used.

Specimen Container

Specimen Preparation

Mix well. Separate from cells within 1 hour of collection. Transfer 1.5 mL plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)

Storage/Transport Temperature

Frozen. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Grossly hemolyzed specimens.

Stability (from collection to initiation)

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months

Notes

Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

Referral Lab

Ordering

Ordering Recommendations

Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

EPIC Order Code

LAB3911

Sunquest Code

PTHRPS

Reference Lab Number

2010677

Synonyms

  • Parathyroid Hormone Related Protein
  • Parathyroid Hormone Related Peptide
  • Humoral Hypercalcemia of Malignancy Factor
  • HHM
  • PTH-RP
  • PTH Related Protein
  • PTH Related Peptide
  • PRP
  • Parathyroid Related Protein
  • Parathyroid Related Polypeptide
  • PTHRP, Plasma
  • PTHrP secretion
  • LAB3911
  • PTHRPS
Fees & Codes

CPT Codes

82542

LOINC

  • 15087-0

Reference Lab Number

2010677
Clinical & Interpretive

Reference Interval

AgeMale
Female
Under 18 yearsNot establishedNot established
18 years and older0.0-2.3 pmol/L0.0-3.4 pmol/L

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Lab Use Only

Test Information

Performing Lab
ARUP
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun, Mon, Wed, Fri
Reported
2-6 days
Additional Technical Information

ARUP Consult®

Disease Topics