Ordering Recommendations

Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

Compliance Statement

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Reference Lab Test Code

PTHRP

Performed

Sun, Mon, Wed, Fri

Turnaround Time

Specimens are sent to the reference laboratory Mon-Sat; results are reported within 2-5 days. 

Use

Aiding in the evaluation of individuals with hypercalcemia of unknown origin or with suspected humoral hypercalcemia of malignancy. 

The test should not be used to exclude cancer or screen individuals with tumors for humoral hypercalcemia of malignancy.

Interpretive Data

Parathyroid hormone-related peptide (PTHrP) can be elevated in pregnant and lactating women and in newborn infants. Nonmalignant conditions that have been described in association with elevated plasma PTHrP levels include systemic lupus erythematosus, HIV-associated lymphadenopathy, lymphedema of chest or pleural cavities, and with benign tumors of the ovary, kidney, and the neuroendocrine system.

Specimen Type

Blood

Collection Containers

Purple on ice

Collection Instructions

Collect into an ice-cooled purple top (EDTA)

Collection Volume

2.0 mL

Minimum Collection Volume

0.7 mL

Specimen Preparation

Centrifuge specimen in a refrigerated centrifuge or in chilled centrifuge cups. Aliquot plasma into plastic vial and freeze.

Unacceptable Conditions

Grossly hemolyzed specimens.

Shipping Instructions

Ship frozen.

Stability (from collection to initiation)

30 days frozen

Containers

Purple (EDTA) on ICE

Reference Interval

≤4.2 pmol/L

Interpretive Data

Parathyroid hormone-related peptide (PTHrP) can be elevated in pregnant and lactating women and in newborn infants. Nonmalignant conditions that have been described in association with elevated plasma PTHrP levels include systemic lupus erythematosus, HIV-associated lymphadenopathy, lymphedema of chest or pleural cavities, and with benign tumors of the ovary, kidney, and the neuroendocrine system.

CPT Disclaimer

The Current Procedural Terminology (CPT) Codes published in the M Health Fairview Test Directory are based on American Medical Association (AMA) guidelines and are provided for informational purposes only. CPT codes are provided only as guidance to assist clients with billing. CPT coding is the responsibility of the billing party. M Health Fairview Laboratories does not assume responsibility for billing errors due to reliance on the CPT codes listed in this Test Directory. Charges may vary due to reflexing, susceptibilities, specimen source, patient age, methodology requirements, etc..

Patient Price Inquiries

Requester Contact Information
Patient and UMP/FV Care Team Fairview Consumer Line at 612-672-1048
MRL Outreach Client dept-mrl-business-assessment@fairview.org
Research research@fairview.org

CPT Codes

CPTQtyHC HospitalPR ClinicNote
82397130082397098239709HC PARATHYROID HORMONE RELATED PEPTIDE PTHRP, MAYO

Methodology

Immunochemiluminometric Assay (ICMA)

MRL Test Build

Test Name Component Required Description Type LOINC
LAB5599     PTH Related Peptide Orderable  
  SRC_1001 Y Blood specimen source: Prompt  
  1230011858   Parathyroid Hormone-Related Peptide (PTHRP) Result 15087-0

Data Type / Multiple Choice Response

SRC_1001
Blood specimen source:
Arm, Left|Arm, Right|Hand, Left|Hand, Right|Blood, Capillary|Other|Peripheral Blood
Default: Peripheral Blood

Contact

For questions regarding the test code Interface Map, please contact DEPT-LAB-CLIENT-INTERFACE@fairview.org
Ordering

Ordering Recommendations

Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.

Compliance Statement

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Reference Lab Test Code

PTHRP

Performed

Sun, Mon, Wed, Fri

Turnaround Time

Specimens are sent to the reference laboratory Mon-Sat; results are reported within 2-5 days. 

Use

Aiding in the evaluation of individuals with hypercalcemia of unknown origin or with suspected humoral hypercalcemia of malignancy. 

The test should not be used to exclude cancer or screen individuals with tumors for humoral hypercalcemia of malignancy.

Interpretive Data

Parathyroid hormone-related peptide (PTHrP) can be elevated in pregnant and lactating women and in newborn infants. Nonmalignant conditions that have been described in association with elevated plasma PTHrP levels include systemic lupus erythematosus, HIV-associated lymphadenopathy, lymphedema of chest or pleural cavities, and with benign tumors of the ovary, kidney, and the neuroendocrine system.
Collection & Processing

Specimen Type

Blood

Collection Containers

Purple on ice

Collection Instructions

Collect into an ice-cooled purple top (EDTA)

Collection Volume

2.0 mL

Minimum Collection Volume

0.7 mL

Specimen Preparation

Centrifuge specimen in a refrigerated centrifuge or in chilled centrifuge cups. Aliquot plasma into plastic vial and freeze.

Unacceptable Conditions

Grossly hemolyzed specimens.

Shipping Instructions

Ship frozen.

Stability (from collection to initiation)

30 days frozen
Containers

Containers

Purple (EDTA) on ICE

Result Interpretation

Reference Interval

≤4.2 pmol/L

Interpretive Data

Parathyroid hormone-related peptide (PTHrP) can be elevated in pregnant and lactating women and in newborn infants. Nonmalignant conditions that have been described in association with elevated plasma PTHrP levels include systemic lupus erythematosus, HIV-associated lymphadenopathy, lymphedema of chest or pleural cavities, and with benign tumors of the ovary, kidney, and the neuroendocrine system.
Administrative

CPT Disclaimer

The Current Procedural Terminology (CPT) Codes published in the M Health Fairview Test Directory are based on American Medical Association (AMA) guidelines and are provided for informational purposes only. CPT codes are provided only as guidance to assist clients with billing. CPT coding is the responsibility of the billing party. M Health Fairview Laboratories does not assume responsibility for billing errors due to reliance on the CPT codes listed in this Test Directory. Charges may vary due to reflexing, susceptibilities, specimen source, patient age, methodology requirements, etc..

Patient Price Inquiries

Requester Contact Information
Patient and UMP/FV Care Team Fairview Consumer Line at 612-672-1048
MRL Outreach Client dept-mrl-business-assessment@fairview.org
Research research@fairview.org

CPT Codes

CPTQtyHC HospitalPR ClinicNote
82397130082397098239709HC PARATHYROID HORMONE RELATED PEPTIDE PTHRP, MAYO

Methodology

Immunochemiluminometric Assay (ICMA)
Interface Mapping

MRL Test Build

Test Name Component Required Description Type LOINC
LAB5599     PTH Related Peptide Orderable  
  SRC_1001 Y Blood specimen source: Prompt  
  1230011858   Parathyroid Hormone-Related Peptide (PTHRP) Result 15087-0

Data Type / Multiple Choice Response

SRC_1001
Blood specimen source:
Arm, Left|Arm, Right|Hand, Left|Hand, Right|Blood, Capillary|Other|Peripheral Blood
Default: Peripheral Blood

Contact

For questions regarding the test code Interface Map, please contact DEPT-LAB-CLIENT-INTERFACE@fairview.org
Private Details

Test Detail

Processing Key



See Processing Key "Special" Definitions document for *SPECIAL* definition.
Abbreviation
PTHRP
Performing Lab
Mayo Medical Laboratories
Department
Reference Laboratory
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