CALFCL (Calprotectin, Fecal) testing is now performed in the IU Health Microbiology Laboratory. Please submit a separate stool specimen for this test in a sterile cup with a CALFCL label.
Additional containers are required for Send Out tests, as well as other stool testing at IU Health Pathology Laboratory. Please access each test on the IU Health Lab Test Directory for additional information.
Collect
Stool, Sterile Container
Preferred Draw Volume
5 grams
Minimum Draw Volume
1 gram
Unacceptable Conditions
Specimens in media or preservatives.
Collection Comments
Transfer 5 grams f stool to an unpreserved stool transport vial (minimum 1.0 g), refrigerate.
Storage/Transport Temperature
Refrigerated/Frozen
Stability (from collection to initiation)
Stool samples should be tested as soon as possible upon receipt, however storage at 2-8°C for up to 72 hours is acceptable.
If samples will not be tested before 72 hours, they should be stored frozen at -20°C or below immediately upon receipt.
Ordering Recommendations
An in vitro diagnostic to aid in the diagnosis of inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis, and to differentiate IBD from irritable bowel syndrome (IBS) in conjunction with other clinical and laboratory findings.
Performed
Monday - Friday
Methodology
Quantitative Chemiluminescent Immunoassay
Reported
2 - 4 days
Performing Lab
Serology
Synonyms
Stool Calprotectin
IBD
IBS
12057
Reference Interval
<50 µg/g Normal
50-120 µg/g Borderline elevated, test should be re-evaluated in 4-6 weeks.
>120 µg/g Elevated
Clinical Interpretation
Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for IBD. Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate.
CPT Codes
83993
LOINC Codes
NAME
LOINC
Order
Calprotectin QN Fecal
38445-3
Test Code (Outreach Synonym)
12057
Catalog Code
10328255701
Collection
Test Information
CALFCL (Calprotectin, Fecal) testing is now performed in the IU Health Microbiology Laboratory. Please submit a separate stool specimen for this test in a sterile cup with a CALFCL label.
Additional containers are required for Send Out tests, as well as other stool testing at IU Health Pathology Laboratory. Please access each test on the IU Health Lab Test Directory for additional information.
Collect
Stool, Sterile Container
Preferred Draw Volume
5 grams
Minimum Draw Volume
1 gram
Unacceptable Conditions
Specimens in media or preservatives.
Collection Comments
Transfer 5 grams f stool to an unpreserved stool transport vial (minimum 1.0 g), refrigerate.
Storage/Transport Temperature
Refrigerated/Frozen
Stability (from collection to initiation)
Stool samples should be tested as soon as possible upon receipt, however storage at 2-8°C for up to 72 hours is acceptable.
If samples will not be tested before 72 hours, they should be stored frozen at -20°C or below immediately upon receipt.
Ordering
Ordering Recommendations
An in vitro diagnostic to aid in the diagnosis of inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis, and to differentiate IBD from irritable bowel syndrome (IBS) in conjunction with other clinical and laboratory findings.
Performed
Monday - Friday
Methodology
Quantitative Chemiluminescent Immunoassay
Reported
2 - 4 days
Performing Lab
Serology
Synonyms
Stool Calprotectin
IBD
IBS
12057
Result Interpretation
Reference Interval
<50 µg/g Normal
50-120 µg/g Borderline elevated, test should be re-evaluated in 4-6 weeks.
>120 µg/g Elevated
Clinical Interpretation
Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for IBD. Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate.
