Plain red or serum separator tube. Also acceptable: Green (sodium heparin), green (lithium heparin), lavender (EDTA), or pink (K2EDTA).
Additional Requirements
Collect: SST
Auto Lab Accepts:
Unacceptable Conditions
Room temperature specimens. Grossly hemolyzed or lipemic specimens.
Specimen Preparation
Centrifuge and remove serum or plasma from cells within 2 hours of collection. Transfer 1.2 mL serum or plasma to an ARUP standard transport tube and refrigerate or freeze immediately. (Min: 0.6 mL)
Ordering Recommendations
Use to evaluate vitamin B12 deficiency in individuals with macrocytic or unexplained anemia, or unexplained neurologic disease. Preferred test is Vitamin B12 with Reflex to Methylmalonic Acid, Serum (Vitamin B12 Status) (0055662).
Storage/Transport Temperature
Frozen.
Stability (from collection to initiation)
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
Performed
Sun-Sat
Reported
1-5 days
Lab info
Specimens are sent by the Core Laboratory to ARUP Laboratory.
Section
Reference Laboratory-ARUP Laboratories
Reference Laboratory Test Code
0099431
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Synonyms
Methylmalonate (Methylmalonic Acid, Serum or Plasma (Vitamin B12 Deficiency))
Cobalamin Deficiency (Methylmalonic Acid, Serum or Plasma (Vitamin B12 Deficiency))
MMA (Methylmalonic Acid, Serum or Plasma (Vitamin B12 Deficiency))
Reference Interval
0.00-0.40 µmol/L
ARUP Test Code
0099431
LOINC
13964-2
CPT Codes
83921
Test Information
EPIC Lab Number
LAB4371
Collect
Plain red or serum separator tube. Also acceptable: Green (sodium heparin), green (lithium heparin), lavender (EDTA), or pink (K2EDTA).
Additional Requirements
Collect: SST
Auto Lab Accepts:
Unacceptable Conditions
Room temperature specimens. Grossly hemolyzed or lipemic specimens.
Specimen Preparation
Centrifuge and remove serum or plasma from cells within 2 hours of collection. Transfer 1.2 mL serum or plasma to an ARUP standard transport tube and refrigerate or freeze immediately. (Min: 0.6 mL)
Ordering Recommendations
Use to evaluate vitamin B12 deficiency in individuals with macrocytic or unexplained anemia, or unexplained neurologic disease. Preferred test is Vitamin B12 with Reflex to Methylmalonic Acid, Serum (Vitamin B12 Status) (0055662).
Storage/Transport Temperature
Frozen.
Stability (from collection to initiation)
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
Performed
Sun-Sat
Reported
1-5 days
Lab info
Specimens are sent by the Core Laboratory to ARUP Laboratory.
Section
Reference Laboratory-ARUP Laboratories
Reference Laboratory Test Code
0099431
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Synonyms
Methylmalonate (Methylmalonic Acid, Serum or Plasma (Vitamin B12 Deficiency))
Cobalamin Deficiency (Methylmalonic Acid, Serum or Plasma (Vitamin B12 Deficiency))
