One 4.5 mL green top with gel (PST), (lithium heparin plasma).)Also acceptable: Gold top (SST); Red top, no gel.
Pediatric Collection
0.5 ml Pediatric PST-Lithium Heparin, Pediatric Red, or Pediatric SST
Unacceptable Conditions
Specimens collected in containers other than specified above.
Storage/Transport Temperature
Internal: Deliver to lab immediately. Offsite: Transport at ambient temperature.
Stability (from collection to initiation)
Room Temp: 24 Hours, Refrigerated: 4 days Frozen: 26 weeks
Epic ID
LAB4311
Interpretive Data
The new NT-proBNP assay has updated reference intervals. These ranges are in alignment with ICON age-dependent cutoffs for improved specificity and eliminating interference from Biotin. The general cutoff for heart failure rule-out in outpatients is 125 pg/mL, but not definitive for every patient. See updated reference intervals and interpretative comments below.
Outpatient Setting For ambulatory patients presenting to outpatient facilities with clinical suspicion of heart failure not previously diagnosed and at least one sign, symptom or risk factor for heart failure, test results should be interpreted as indicated in the table below.
Results (pg/mL)
Age (years)
Interpretation
<125
All
Negative: Heart failure Unlikely
≥ 125
All
Consider Heart Failure as well as other caused of NT-proBNP elevation
Emergency Department (ED) Setting For patients presenting to Emergency Department/acute settings with acute or worsening dyspnea and clinical suspicion of heart failure, NT-proBNP test results should be interpreted as indicated in the table below:
Results (pg/mL)
Age (years)
Interpretation
<300
All
Negative: Heart failure Unlikely
≥300 to <450
22-49
Gray Zone: Result Indeterminate-Consider other caused of NT-proBNP elevation
One 4.5 mL green top with gel (PST), (lithium heparin plasma).)Also acceptable: Gold top (SST); Red top, no gel.
Pediatric Collection
0.5 ml Pediatric PST-Lithium Heparin, Pediatric Red, or Pediatric SST
Unacceptable Conditions
Specimens collected in containers other than specified above.
Storage/Transport Temperature
Internal: Deliver to lab immediately. Offsite: Transport at ambient temperature.
Stability (from collection to initiation)
Room Temp: 24 Hours, Refrigerated: 4 days Frozen: 26 weeks
Ordering
Epic ID
LAB4311
Result Interpretation
Interpretive Data
The new NT-proBNP assay has updated reference intervals. These ranges are in alignment with ICON age-dependent cutoffs for improved specificity and eliminating interference from Biotin. The general cutoff for heart failure rule-out in outpatients is 125 pg/mL, but not definitive for every patient. See updated reference intervals and interpretative comments below.
Outpatient Setting For ambulatory patients presenting to outpatient facilities with clinical suspicion of heart failure not previously diagnosed and at least one sign, symptom or risk factor for heart failure, test results should be interpreted as indicated in the table below.
Results (pg/mL)
Age (years)
Interpretation
<125
All
Negative: Heart failure Unlikely
≥ 125
All
Consider Heart Failure as well as other caused of NT-proBNP elevation
Emergency Department (ED) Setting For patients presenting to Emergency Department/acute settings with acute or worsening dyspnea and clinical suspicion of heart failure, NT-proBNP test results should be interpreted as indicated in the table below:
Results (pg/mL)
Age (years)
Interpretation
<300
All
Negative: Heart failure Unlikely
≥300 to <450
22-49
Gray Zone: Result Indeterminate-Consider other caused of NT-proBNP elevation
