The ME panel may not be optimal for cryptococcal meningitis. Cryptococcal antigen, which includes fungal culture, should be ordered if there is a clinical suspicion for cryptococcal infection.
Aerobic culture and gram stain are automatically reflexed when ME panel is ordered.
Collection Instructions
Meningitis panel is extremely sensitive, which can lead to false positives for organisms that are carried in the respiratory tract of healthy individuals. All personnel in the room should be masked when lumbar punctures are performed.
Collect
CSF from lumbar puncture - tube 3 or 4 or shunt fluid
Storage/Transport Temperature
Transport specimen to laboratory at room temperature
Remarks
Includes the following targets: Bacterial
E. coli K1
Haemophilus influezena
Listeria monocytogenes
Neisseria meningitides
Streptococcus agalactiae
Streptococcus pneumoniae Viruses
Cytomegalovirus
Enterovirus
Herpes simplex 1/2
Human herpes virus 6
Human parechovirus
Varicella zoster virus Yeast
Cryptococcus neoformans/gatti
Positive HHV-6 does not necessarily correlate with clinical disease. Latent infection, chromosomal integration, and asymptomatic reactivation may occur. Interpret positive HHV-6 results in association with clinical symptoms and supplemental laboratory testing. An Infectious Disease consultation is recommended.
Specimens positive for CMV, HSV1&2, Varicella zoster will be sent for confirmation/quantitation
HHV-6 will be sent upon request
Reference Interval
Not Detected
CPT Codes
87483
LOINC Mapping
82180-1
Order Type (Individual or Group)
I
Result Test ID
MENCP
Reportable?
Y
Result Test Name
MENINGITIS/ENCEPHALITIS PCR PANEL
Result Type (Individual or Group)
I
Type (Alpha or Numeric)
N
Default Result
See Micro
Micro Source Information
SOURCE ID
SOURCE NAME
SITES
REFLEX TESTS
CSFLP
CSF: LUMBAR PUNCTURE
TUBE #1
TUBE #2
TUBE #3
TUBE #4
CSFVP
CSF: SHUNT OR DEVICE
CPT Codes
87483
LOINC Mapping
82180-1
Pricing
Refer to Lab Account Manager. email: labservicesoutreach@urmc.rochester.edu
Specimen Requirements
Ordering Recommendations
The ME panel may not be optimal for cryptococcal meningitis. Cryptococcal antigen, which includes fungal culture, should be ordered if there is a clinical suspicion for cryptococcal infection.
Aerobic culture and gram stain are automatically reflexed when ME panel is ordered.
Collection Instructions
Meningitis panel is extremely sensitive, which can lead to false positives for organisms that are carried in the respiratory tract of healthy individuals. All personnel in the room should be masked when lumbar punctures are performed.
Collect
CSF from lumbar puncture - tube 3 or 4 or shunt fluid
Storage/Transport Temperature
Transport specimen to laboratory at room temperature
Remarks
Includes the following targets: Bacterial
E. coli K1
Haemophilus influezena
Listeria monocytogenes
Neisseria meningitides
Streptococcus agalactiae
Streptococcus pneumoniae Viruses
Cytomegalovirus
Enterovirus
Herpes simplex 1/2
Human herpes virus 6
Human parechovirus
Varicella zoster virus Yeast
Cryptococcus neoformans/gatti
Positive HHV-6 does not necessarily correlate with clinical disease. Latent infection, chromosomal integration, and asymptomatic reactivation may occur. Interpret positive HHV-6 results in association with clinical symptoms and supplemental laboratory testing. An Infectious Disease consultation is recommended.
