Collect

Preferred
Tube Name Blue
Optimum Volume Full
Minimum Volume Full

Specimen Preparation

Prior to freezing, collection tubes must be centrifuged at a time and speed that results in the production of  a platelet poor plasma which contains a residual platelet count of <10,000/uL.

Unacceptable Conditions

Serum. EDTA Plasma, Clotted, Hemolyzed specimens &/or  Improperly labeled  or filled  collection tube.

Storage/Transport Temperature

Whole Blood (Spun or Unspun) can be  transported or stored  at Room Temperature (18-24oC). for up to 24 hours.
Platelet Poor Plasma Separated from the cells can be transported or stored Frozen at -20oC for up to 2 weeks.

Stability (from collection to initiation)

Whole Blood (Spun or Unspun) stored at Room Temperature (18-24oC) for 24 hours.
Platelet Poor Plasma Separated from the cells and Frozen at -20oC for up to 2 weeks.

Cerner Orderable(s)

PT 1:1 Mix

Performed

St. Joseph's Hospital and Winter Haven Hospital.

24/7

Ordering Recommendations

Mixing studies are tests performed on a blood plasma specimen that has an unexplained abnormal PT test result.  In the procedure, the Plasma Specimen is mixed with Normal Pool Plasma and retested.  The result obtained is used to aid in an evaluation to distinguish factor deficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against factor VIII.

Methodology

Clot Detection and Analysis by Spectrophotometric Evaluation

Reported

Within 24 hours

Synonyms

  • Protime Correction
  • PT 1:1 Mix
  • PT Correction
  • PT Inhibitor Assay
  • PT Mixing Study
  • Circulating Anticoagulant
  • Prothrombin Time 1:1 Mix
  • Prothrombin Time Inhibitor Assay
  • Prothrombin Time Mixing Study

Reference Interval

Components Reference Interval
Patient Prothrombin Time (PT) 9.8-13.3 seconds
Prothrombin Time (PT) 9.8-13.3 seconds

Interpretive Data

Testing performed on 1:1 Mix of Patient Plasma with Normal Plasma.

The presence of interfering anticoagulant drugs such as heparin or direct thrombin inhibitors cannot be excluded as a cause for an abnormal mixing study result.

CPT Codes

85611
Collection

Collect

Preferred
Tube Name Blue
Optimum Volume Full
Minimum Volume Full

Specimen Preparation

Prior to freezing, collection tubes must be centrifuged at a time and speed that results in the production of  a platelet poor plasma which contains a residual platelet count of <10,000/uL.

Unacceptable Conditions

Serum. EDTA Plasma, Clotted, Hemolyzed specimens &/or  Improperly labeled  or filled  collection tube.

Storage/Transport Temperature

Whole Blood (Spun or Unspun) can be  transported or stored  at Room Temperature (18-24oC). for up to 24 hours.
Platelet Poor Plasma Separated from the cells can be transported or stored Frozen at -20oC for up to 2 weeks.

Stability (from collection to initiation)

Whole Blood (Spun or Unspun) stored at Room Temperature (18-24oC) for 24 hours.
Platelet Poor Plasma Separated from the cells and Frozen at -20oC for up to 2 weeks.
Ordering

Cerner Orderable(s)

PT 1:1 Mix

Performed

St. Joseph's Hospital and Winter Haven Hospital.

24/7

Ordering Recommendations

Mixing studies are tests performed on a blood plasma specimen that has an unexplained abnormal PT test result.  In the procedure, the Plasma Specimen is mixed with Normal Pool Plasma and retested.  The result obtained is used to aid in an evaluation to distinguish factor deficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against factor VIII.

Methodology

Clot Detection and Analysis by Spectrophotometric Evaluation

Reported

Within 24 hours

Synonyms

  • Protime Correction
  • PT 1:1 Mix
  • PT Correction
  • PT Inhibitor Assay
  • PT Mixing Study
  • Circulating Anticoagulant
  • Prothrombin Time 1:1 Mix
  • Prothrombin Time Inhibitor Assay
  • Prothrombin Time Mixing Study
Result Interpretation

Reference Interval

Components Reference Interval
Patient Prothrombin Time (PT) 9.8-13.3 seconds
Prothrombin Time (PT) 9.8-13.3 seconds

Interpretive Data

Testing performed on 1:1 Mix of Patient Plasma with Normal Plasma.

The presence of interfering anticoagulant drugs such as heparin or direct thrombin inhibitors cannot be excluded as a cause for an abnormal mixing study result.
Administrative

CPT Codes

85611

×
Learn More Remind Me Later Dismiss